Elementary simulation of tethered Brownian motion

American Journal of Physics

Volumn 75, Issue 6, 2007, Pages 520-523

  Beausang, John F ^a   Zurla, Chiara ^b   Finzi, Laura ^b   Sullivan, Luke ^c   Nelson, Philip C ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b EMORY UNIVERSITY   (United States)

^c URSINUS COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 34250738929     PISSN: 00029505     EISSN: None     Source Type: Journal    
DOI: 10.1119/1.2710484     Document Type: Article

References (12)

1. H. Berg, Random Walks in Biology (Princeton U. P., Princeton, NJ, 1993), 2nd ed.
2. P. Nelson, Biological Physics: Energy, Information, Life (Freeman, New York, 2004).
3. F. Reif, Fundamentals of Statistical and Thermal Physics (McGraw-Hill, New York, 1965), Sec. 15.10.
4. See EPAPS Document No. E-AJPIAS-75-013704 for simulation software. This document can be reached via a direct link in the online article's HTML reference section or via the EPAPS homepage (http://www.aip.org/pubservs/epaps.html).
5. F. Gittes and C. F. Schmidt, "Signals and noise in micromechanical measurements" in Laser Tweezers in Cell Biology, edited by M. P. Sheetz (Academic, San Diego CA, 1998), pp. 129-156.
6. L. Finzi and J. Gelles, "Measurement of lactose represser-mediated loop formation and breakdown in single DNA molecules," Science 267, 378-380 (1995).
7. P. C. Nelson, C. Zurla, D. Brogioli, J. F. Beausang, L. Finzi, and D. Dunlap, "Tethered particle motion as a diagnostic of DNA tether length," J. Phys. Chem. B 110, 17260-17267 (2006).
8. D. E. Segall, P. C. Nelson, and R. Phillips, "Volume-exclusion effects in tethered-particle experiments: Bead size matters," Phys. Rev. Lett. 96, 088306-1-4 (2006).
9. E. Purcell, "Life at low Reynolds number," Am. J. Phys. 45, 3-10 (1977).
10. J. Happel and H. Brenner, Low Reynolds Number Hydrodynamics (Martinus Nijhoff, The Hague, 1983).
11. E. Schäffer, S. F. Norrelykke, and J. Howard, "Surface forces and drag coefficients of microspheres near a plane surface measured with optical tweezers," Langmuir (in press).
12. eff, which we expect to be larger than the value appropriate to water in bulk.