Should all patients undergoing breast conserving therapy for DCIS receive radiation therapy? No. One size does not fit all: An argument against the routine use of radiation therapy for all patients with ductal carcinoma in situ of the breast who elect breast conservation

Journal of Surgical Oncology

Volumn 95, Issue 8, 2007, Pages 605-609

  Silverstein, Melvin J ^a,c   Lagios, Michael D ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Breast Consultation Service   (United States)

^c Department of Breast Cancer Research ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CARCINOMA; BREAST DUCT; CANCER PATIENT; CANCER RECURRENCE; CANCER SIZE; CANCER SURVIVAL; CLINICAL TRIAL; CONSERVATIVE TREATMENT; CONTROLLED CLINICAL TRIAL; COST BENEFIT ANALYSIS; DISEASE FREE SURVIVAL; EDITORIAL; HUMAN; INTERMETHOD COMPARISON; LUNG VOLUME; MASTECTOMY; PRIORITY JOURNAL; RADIATION SICKNESS; RANDOMIZED CONTROLLED TRIAL; RISK BENEFIT ANALYSIS; TREATMENT OUTCOME;

EID: 34250731655     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.20708     Document Type: Editorial

References (34)

1. Bijker N, Meijnen P, Peterse J, et al.: Breast conserving treatment with or without radiotherapy in ductal carcinoma in situ: Ten-year results of European organization for research and treatment of cancer randomized phase III trial 10853 - A study by the EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Group. J Clin Oncol 2006;24:1-8.
2. UK Coordinating Committee on Cancer Research (UKCCCR): Ductal Carcinoma in Situ (DCIS) working party, radiotherapy and tamoxifen in women with completely excised ductal carcinoma in situ of the breast in the UK, Australia, and New Zealand: randomised controlled trial. Lancet 2003;362:95-102.
3. Fisher B, Land S, Mamounas E, et al.: Prevention of invasive breast cancer in women with ductal carcinoma in situ: An update of the National Surgical Adjuvant Breast and Bowel Project Experience. Semin Oncol 2001;28:400-418.
4. Sposto R, Epstein M, Silverstein MJ: Predicting local recurrence in patients with ductal carcinoma in situ of the breast. In: Silverstein MJ, Recht A, Lagios M, editors. Ductal carcinoma in situ of the breast, Philadelphia: Lippincott, Williams and Wilkins; 2002, 255-263.
5. Bijker N, Peterse J, Duchateau L, et al.: Risk factors for recurrence and metastasis after breast-conserving therapy for ductal carcinoma in situ: Analysis of European organization for research and treatment of cancer trial 10853. J Clin Oncol 2001;19:2263-2271.
6. Fisher B, Costantino J, Redmond C, et al.: Lumpectomy compared with lumpectomy and radiation therapy for the treatment of intraductal breast cancer. N Engl J Med 1993;328:1581-1586.
7. Silverstein MJ, Buchanan C: Ductal carcinoma in situ: USC/Van nuys prognostic index and the impact of margin status. The Breast 2003;12:457-471.
8. Silverstein MJ: The University of Southern California/Van nuys prognostic index for ductal carcinoma in situ of the breast. Am J Surg 2003;186:337-343.
9. Silverstein MJ: An argument against routine use of radiotherapy for ductal carcinoma in situ. Oncology 2003;17:1511-1546.
10. Romero L, Klein L, Ye W, et al.: Outcome after invasive recurrence in patients with ductal carcinoma in situ of the breast. Am J Surg 2004;188:371-376.
11. Silverstein MJ, Lagios M, Martino S, et al.: Outcome after local recurrence in patients with ductal carcinoma in situ of the breast. J Clin Oncol 1998;16:1367-1373.
12. Surveillance Epidemiology and End Results (SEER) Program: P-ud-NCI, DCCPS Surveillance Research Program, Cancer Statistics Branch. www.seer.cancer.gov (released April 2004), Public use data. 2004.
13. Early Breast Cancer Trialists' Collaborative Group: Favorable and unfavorable effects on long-term survival of radiotherapy for early breast cancer. Lancet 2000;355:1757-1770.
14. Holland R, Faverly D: Whole organ studies. Ductal carcinoma in situ of the breast, Silverstein M, editor. Baltimore: Williams and Wilkins; 1997, 233-240.
15. Holland R, Faverly D: Whole organ studies, in ductal carcinoma in situ of the breast, Silverstein MJ, Recht A, Lagios M, editors. Philadelphia: Lippincott, Williams and Wilkins; 2002, pp 240-254.
16. Holland R, Hendriks J, Verbeek A, et al.: Extent, distribution, and mammographic/histological correlations of breast ductal carcinoma in situ. Lancet 1990;335:519-522.
17. Holland R, Hendriks J: Microcalcifications associated with ductal carcinoma in situ: mammographic-pathologic correlation. Semin Diag Pathol 1994;11:181-192.
18. Holland R, Peterse J, Millis R, et al.: Ductal carcinoma in situ: A proposal for a new classification. Semin Diag Pathol 1994;11:167-180.
19. Faverly D, Burgers L, Bult P, et al.: Three dimensional imaging of mammary ductal carcinoma is situ: Clinical implications. Semin in Diag Pathol 1994;11:193-198.
20. Page D, Dupont W, Roger L, et al.: Intraductal carcinoma of the breast: Follow-up after biopsy only. Cancer 1982;49:751-758.
21. Page D, Dupont W, Roger L, et al.: Atypical hyperplastic lesions of the female breast. A log-term follow-up study. Cancer 1985;55:2698-2708.
22. Page D, Dupont W, Rogers L, et al.: Continued local recurrence of carcinoma 15-25 years after a diagnosis of low grade ductal carcinoma in situ of the breast treated only by biopsy. Cancer 1995;76:1197-1200.
23. Lagios M: Controversies in diagnosis, biology, and treatment. Breast J 1995;1:68-78.
24. Page D, Rogers L, Schuyler P, et al.: The natural history of ductal carcinoma in situ of the breast, In Silverstein MJ, Recht A, Lagios M, editors. Ductal carcinoma in situ of the breast, Philadelphia: Lippincott, Williams and Wilkins; 2002, 17-21.
25. Sanders M, Schuyler P, Dupont W, et al.: The natural history of low-grade ductal carcinoma in situ of the breast in women treated by biopsy only revealed over 30 years of long-term follow-up. Cancer 2005;103:2481-2484.
26. Group, EBCTC: Favorable and unfavorable effects on long-term survival of radiotherapy for early breast cancer: An overview of the randomized trials. Lancet 2006;2000:1757-1770.
27. Giordano S, Kuo Y, Freeman J, et al.: Risk of cardiac death after adjuvant radiotherapy for breast cancer. J Natl Cancer Inst 2005;97:419-424.
28. Darby S, McGale P, Taylor C, et al.: Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: Prospective cohort study of about 300,000 women un US SEER cancer registries. Lancet Oncol 2005;6:557-565.
29. Zablotska L, Neugut A: Lung carcinoma after radiation therapy in women treated with lumpectomy or mastectomy for primary breast carcinoma. Cancer 2003;97:1404-1411.
30. Darby S, McGale P, Peto R, et al.: Mortality from cardiovascular disease more than 10 years after radiotherapy for breast cancer: Nationwide cohort study of 90,000 Swedish women. BMJ 2003;326:256-257.
31. Wong J, Kaelin C, Troyan S, et al.: Prospective study of wide excision alone for ductal carcinoma in situ of the breast. J Clin Oncol 2006;24:1031-1036.
32. Lagios M, Page D, Silverstein M: Prospective study of wide excision alone for ductal carcinoma in situ of the breast [comment]. J Clin Oncol 2006;24:3809-8811.
33. Silverstein MJ, Waisman J: Outcome after invasive local recurrence in patients with ductal carcinoma in situ of the breast. In: Silverstein MJ, Recht A, Lagios M, editors. Ductal carcinoma in situ of the breast. Philadelphia: Lippincott, Williams and Wilkins; 2002, 545-553.
34. Schwartz G: Treatment of subclinical ductal carcinoma in situ of the breast by local excision and surveillance: An updated personal experience. In: Silverstein MJ, Recht A, Lagios M, editors. Ductal carcinoma in situ of the breast. Philadelphia: Lippincott, Williams and Wilkins; 2002, 308-321.