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Volumn , Issue 9, 2007, Pages 1379-1382

Magnesium perchlorate: An efficient catalyst for one-pot synthesis of pyrano- and furanoquinolines

Author keywords

Aldehydes; Anilines; Furanoquinolines; Magnesium perchlorate; One pot; Pyranoquinolines

Indexed keywords

2,3 DIHYDROFURAN; 3,4 DIHYDRO 2H PYRAN; ALDEHYDE DERIVATIVE; ANILINE DERIVATIVE; BENZALDEHYDE; MAGNESIUM PERCHLORATE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 34250716988     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-980354     Document Type: Article
Times cited : (17)

References (37)
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    • Trost, B. M, Fleming, I, Eds, Pergamon: Oxford
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  • 37
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    • General Experimental Procedure A mixture of the aniline (5 mmol, aldehyde (5 mmol, dihydropyran or dihydrofuran (7 mmol, Mg(ClO 4)2 (0.25 mmol, 5 mol, in MeCN (2 mL) was stirred at r.t. for an appropriate time (Table 1, After completion of the reaction, as indicated by TLC, the reaction mixture was diluted with EtOAc (2 x 10 mL) and washed with H2O (2 x 10 mL) followed by brine (2 x 15 mL, The combined organic extracts were dried over Na2SO4, concentrated in vacuo and purified by column chromatography on silica gel (Merck, 100-200 mesh; EtOAc-hexane, 1:9) to afford the pure pyrano- or furanoquinoline. Spectral data of selected compounds: Compound 4j: IR (KBr, 3325 cm-1. 1H NMR (200 MHz, CDCl3, δ, 1.35 (m, 1 H, 1.50 (m, 1 H, 1.65 (m, 1 H, 1.85 (m, 1 H, 2.15 (m, 1 H, 3.75 (m, 1 H, 3.90 (br s, 1 H, 4.15 (m, 1 H, 4.40 (d, J, 2.8 Hz, 1 H, 4.70 d, J
    • + + 1].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.