Transportation stress in young bulls alters expression of neutrophil genes important for the regulation of apoptosis, tissue remodeling, margination, and anti-bacterial function

Veterinary Immunology and Immunopathology

Volumn 118, Issue 1-2, 2007, Pages 19-29

  Buckham Sporer, K R ^a,b,c   Burton, J L ^c   Earley, B ^b   Crowe, M A ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b GRANGE RESEARCH CENTRE   (Ireland)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Beef cattle; Cortisol; Gene expression; Neutrophils; Transportation stress

Indexed keywords

BETA GLUCAN; FAS ANTIGEN; GELATINASE B; GLUCOCORTICOID; HYDROCORTISONE; L SELECTIN;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; APOPTOSIS; ARTICLE; BACTERICIDAL ACTIVITY; BLOOD; BULL (BOVINE); CELL FUNCTION; CELL ISOLATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HYDROCORTISONE BLOOD LEVEL; NEUTROPHIL; NEUTROPHIL COUNT; NONHUMAN; PLASMA; TRANSPORT STRESS; UPREGULATION; WOUND HEALING;

ANIMAL HUSBANDRY; ANIMAL WELFARE; ANIMALS; APOPTOSIS; BACTERIA; CATTLE; GENE EXPRESSION REGULATION; MALE; NEUTROPHILS; STRESS; TIME FACTORS; TRANSPORTATION;

ANIMALIA; BACTERIA (MICROORGANISMS); BOS; FRIESIA;

EID: 34250692991     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2007.04.002     Document Type: Article

References (46)

1. Arthington J.D., Eicher S.D., Kunkle W.E., and Martin F.G. Effect of transportation and commingling on the acute-phase response, growth, and feed intake of newly weaned beef calves. J. Anim. Sci. 81 (2003) 1120-1125
2. Bamberger C.M., Schulte H.M., and Chrousos G.P. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocr. Rev. 17 3 (1996) 245-261
3. Bartram U., and Speer C.P. The role of transforming growth factor β in lung development and disease. Chest 125 (2004) 754-765
4. Blecha F., Boyles S.L., and Riley J.G. Shipping suppresses lymphocyte blastogenic responses in Angus and Brahman × Angus feeder calves. J. Anim. Sci. 59 3 (1984) 576-583
5. Burton J.L., and Kehrli Jr. M.E. Regulation of neutrophil adhesion molecules, and shedding of Staphylococcus aureus in milk of cortisol- and dexamethasone-treated cows. Am. J. Vet. Res. 56 (1995) 997-1006
6. Burton J.L., Kehrli Jr. M.E., Kapil S., and Horst R.L. Regulation of l-selectin and CD18 on bovine neutrophils by glucocorticoids: effects of cortisol and dexamethasone. J. Leukoc. Biol. 57 (1995) 317-325
7. Burton J.L., Madsen S.A., Chang L.-C., Weber P.S.D., Buckham K.R., van Dorp R., Hickey M.-C., and Earley B. Gene expression signatures in neutrophils exposed to glucocorticoids: A new paradigm to help explain "neutrophil dysfunction" in parturient dairy cows. Vet. Immun. Immunopath. 105 (2005) 197-219
8. Calafat J., Janssen H., Knol E.F., Malm J., and Egesten A. The bactericidal/permeability-increasing protein (BPI) is membrane-associated in azurophil granules of human neutrophils, and relocation occurs upon cellular activation. Acta Pathol. Microbiol. Immunol. Scand. 108 (2000) 201-208
9. Chakrabarti S., and Patel K.D. Regulation of matrix metalloproteinase-9 release from IL-8-stimulated human neutrophils. J. Leukoc. Biol. 78 1 (2005) 279-288
10. Chang L.-C., Madsen S.A., Toelboell T., Weber P.S.D., and Burton J.L. Effects of glucocorticoids on Fas gene expression in bovine blood neutrophils. J. Endocrinol. 183 (2004) 569-583
11. Chirase N.K., Greene W., Purdy C.W., Loan R.W., Auvermann B.W., Parker D.B., Walborg E.F., Steveson D.E., Xu Y., and Klaunig J.E. Effect of transportation stress on respiratory disease, serum antioxidant status, and serum concentrations of lipid peroxidation biomarkers in beef cattle. Am. J. Vet. Res. 65 (2004) 860-864
12. Cox G. The role of neutrophils in inflammation. Can. Respir. J. 5 Suppl. A (1998) 37A-40A
13. Crookshank H.R., Elissalde M.H., White R.G., Clanton D.C., and Smalley H.E. Effect of transportation and handling of calves upon blood serum composition. J. Anim. Sci. 48 3 (1979) 430-435
14. Deitch E.A., Ananthakrishnan P., Cohen D.B., Xu D.Z., Feketeova E., and Hauser C.J. Neutrophil activation is modulated by sex hormones after trauma-hemorrhagic shock and burn injuries. Am. J. Physiol. Heart Circ. Physiol. 291 (2006) H1456-H1645
15. Dixit V.D., Marahrens M., and Parvizi N. Transportation stress modulates adrenocrorticotropin secretion from peripheral bovine lymphocytes. J. Anim. Sci. 79 (2001) 729-734
16. Eruslanov E.B., Lyadova I.V., Kondratieva T.K., Majorov K.B., Scheglov I.V., Orlova M.O., and Apt A.S. Neutrophil responses to Mycobacterium tuberculosis infection in genetically susceptible and resistant mice. Infect. Immun. 73 3 (2005) 1744-1753
17. 2 space allowance. Livest. Prod. Sci. 51 (1997) 245-254
18. Fligiel S.E.G., Standiford T., Fligiel H.M., Tashkin D., Strieter R.M., Warner R.L., Johnson K.J., and Varani J. Matrix metalloproteinases and matrix metalloproteinase inhibitors in acute lung injury. Human Pathol. 37 (2006) 422-430
19. Gaillard R.C., and Spinedi E. Sex- and stress-steroids interactions and the immune system: evidence for a neuroendocrine-immunological sexual dimorphism. Domest. Anim. Endocrinol. 15 (1998) 345-352
20. Galyean M.L., Perino L.J., and Duff G.C. Interaction of cattle health/immunity and nutrition. J. Anim. Sci. 77 (1999) 1120-1134
21. Graham W.R. The pathology of shipping fever in feedlot cattle. J. Am. Vet. Med. Assoc. 123 (1953) 198-203
22. Gupta, S., Earley, B., Crowe, M.A., 2006. Effect of 12-h road transportation on physiological, immunological, and haematological parameters in bulls housed at different space allowances. Vet. J., doi:10.1016/j.tvjl.2006.02.011 (Epub ahead of print).
23. Hernandez-Pando R., Orozco-Esteves H., Maldonado H.A., Aguilar-León D., Vilchis-Landeros M.M., Mata-Espinosa D.A., Mendoza V., and López-Casillas F. A combination of a transforming growth factor-β antagonist and an inhibitor of cyclooxygenase is an effective treatment for murine pulmonary tuberculosis. Clin. Exp. Immunol. 144 (2006) 264-272
24. Kansas G.S. Selectins and their ligands: current concepts and controversies. Blood 88 9 (1996) 3259-3287
25. Lekeux P. Bovine respiratory disease complex: an European perspective. Bov. Pract. 29 (1995) 71-75
26. Madsen S.A., Weber P.S.D., and Burton J.L. Altered expression of cellular genes in neutrophils of periparturient dairy cows. Vet. Immun. Immunopathol. 86 (2002) 159-175
27. Madsen S.A., Chang L.-C., Hickey M.-C., Rosa G.J.M., Coussens P.M., and Burton J.L. Microarray analysis of gene expression in blood neutrophils of parturient cows. Physiol. Genom. 16 (2004) 212-221
28. Madsen-Bouterse S.A., Rosa G.J.M., and Burton J.L. Glucocorticoid modulation of Bcl-2 family members A1 and Bak during delayed spontaneous apoptosis of bovine blood neutrophils. Endocrinology 147 8 (2006) 3826-3834
29. Moraes T.J., Zurawska J.H., and Downey G.P. Neutrophil granule contents in the pathogenesis of lung injury. Curr. Opin. Hematol. 13 (2006) 21-27
30. Murata H., Takahashi H., and Matsumoto H. The effects of road transportation on peripheral blood lymphocyte subpopulations, lymphocyte blastogenesis and neutrophil function in calves. Br. Vet. J. 143 (1987) 166-174
31. Nishimura H., Gogami A., Miyagawa Y., Nanbo A., Murakami Y., Baba T., and Nagasawa S. Bactericidal/permeability-increasing protein promotes complement activation for neutrophil-mediated phagocytosis on bacterial surface. Immunology 103 (2001) 519-525
32. Preisler M.T., Weber P.S.D., Tempelman R.J., Erskine R.J., Hunt H., and Burton J.L. Glucocorticoid receptor down-regulation in neutrophils of periparturient cows. Am. J. Vet. Res. 61 1 (2000) 14-19
33. Roth J.A., and Kaeberle M.L. Effects of in vivo dexamethasone administration on in vitro bovine polymorphonuclear leukocyte function. Infect. Immun. 33 2 (1981) 434-441
34. Ryff J.F., and Glenn M.W. Possible evidence of a viral agent in shipping fever complex of cattle. J. Am. Vet. Med. Assoc. 131 (1957) 469-470
35. SAS Institute, Version 9.1. Copyright 2002-2003. SAS Institute, Inc., Cary, NC.
36. Tarrant P.V., Kenny F.J., Harrington D., and Murphy M. Long distance transportation of steers to slaughter: effect of stocking density on physiology, behaviour, and carcass quality. Livest. Prod. Sci. 30 (1992) 223-238
37. Tempelman R.J., Saama P.M., Freeman A.E., Kelm S.C., Kuck A.L., Kehrli Jr. M.E., and Burton J.L. Genetic variation in bovine neutrophil sensitivity to glucocorticoid challenge. Acta Agric. Scand. 52 (2002) 189-202
38. Van Eeden S.F., Miyagashima R., Haley L., and Hogg J.C. l-Selectin expression increases on peripheral blood polymorphonuclear leukocytes during active marrow release. Am. J. Respir. Crit. Care. Med. 151 (1995) 500-507
39. Van Eeden S.F., Kitagawa Y., Klut M.E., Lawrence E., and Hogg J.C. Polymorphonuclear leukocytes released from the bone marrow preferentially sequester in lung microvessels. Microcirculation 4 3 (1997) 369-380
40. Verthelyi D. Sex hormones as immunomodulators in health and disease. Int. Immunopharm. 1 (2001) 983-993
41. Weber P.S.D., Madsen S.A., Smith G.W., Ireland J.J., and Burton J.L. Pre-translational regulation of neutrophila l-selectin in glucocorticoid-challenged cattle. Vet. Immunol. Immunopathol. 83 (2001) 213-240
42. Weber P.S.D., Toelboell T., Chang L.-C., Tirrell J.D., Saama P.M., Smith G.W., and Burton J.L. Mechanisms of glucocorticoid-induced down-regulation of neutrophil l-selectin in cattle: evidence for effects at the gene-expression level and primarily on blood neutrophils. J. Leukoc. Biol. 75 (2004) 815-827
43. Weber P.S.D., Madsen-Bouterse S.A., Rosa G.J.M., Sipkovsky S., Ren X., Almeida P.E., Kruska R., Halgren R.G., Barrick J.L., and Burton J.L. Analysis of the bovine neutrophil transcriptome during glucocorticoid treatment. Physiol. Genom. 28 1 (2006) 97-112
44. Weiss S.J. Tissue destruction by neutrophils. N. Engl. J. Med. 320 6 (1989) 365-376
45. Yagi Y., Shiono H., Chikayama Y., Ohnuma A., Nakamura I., and Yayou K.-I. Transportation stress increases somatic cell counts in milk, and enhances the migration capacity of peripheral blood neutrophils of dairy cows. Clin. Pathol. 66 4 (2004) 381-387
46. Zhang X., Ding L., and Sandford A.J. Selection of reference genes for gene expression studies in human neutrophils by real-time PCR. BMC Mol. Biol. 6 4 (2005)