Effects of L-alanyl-L-glutamine dipeptide administration during 35 days of postnatal life on intestinal mucosa, bone properties, and performance of piglets in their early post-weaning period

Bulletin of the Veterinary Institute in Pulawy

Volumn 51, Issue 1, 2007, Pages 125-129

  PawŁowska, Marta ^a   Piedra, Jose Luis Valverde ^a   Filip, Rafał ^e   Szymańczyk, Sylwia Edyta ^a   Kapica, MaŁgorzata ^a   Puzio, Iwona ^a   Skrzypek, Henryk ^b   Gawron, Antoni ^c   Pierzynowski, Stefan Grzegorz ^d   Studziński, Tadeusz ^a  

^a UNIVERSITY OF LIFE SCIENCES IN LUBLIN   (Poland)

^b JOHN PAUL II CATHOLIC UNIVERSITY OF LUBLIN   (Poland)

^c MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

^d LUND UNIVERSITY   (Sweden)

^e INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

Author keywords

Femur; Glutamine; Piglets; Small intestine; Weaning

Indexed keywords

EID: 34250686071     PISSN: 00424870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Bertolo R.F., Brunon J.A., Pencharz P.B., Ball R.O.: Arginine, ornithine, and proline interconversion is dependent on small intestinal metabolism in neonatal piglets. Am J Physiol Endocrinol Metab 2003, 284, E915-E922.
2. Bieńko M., Radzki R.P., Puzio I., Filip R., Pierzynowski S.G.: The influence of alpha-ketoglutarate (AKG) on mineralization of femur in rats with established osteopenia. Acta Orthop Scand 2002, Suppl. 304, 73, 52.
3. Biernat M., Zabielski R., Sysa P., Sosak-Świderska B., Le Huerou-Luron I., Guilloteau P.: Small intestinal and pancreatic microstructures are modified by an intraduodenal CCK-A receptor antagonist administration in neonatal calves. Regul Pept 1999, 23, 77-85.
4. Brosnan JT, Lowry M, Vinay P, Gougoux A, Halperin ML.: Renal ammonium production - une vue canadienne. Can J Physiol Pharmacol 1987, 65, 489-498.
5. Chenu C.: Glutamatergic regulation of bone resorption. J Musculoskel Neuron Interact 2002, 2, 423-431.
6. Den Hond E., Hiele M., Peelers M., Ghoos Y., Rutgeerts P.: Effect of long-term oral glutamine supplements on small intestinal permeability in patients with Crohn's disease, J Parenter Enterai Nutr 1999, 23, 7-11.
7. Ferretti J.L., Capozza R.F., Mondelo N., Zanchetta J.R.: Interrelationships between densitometric, geometric, and mechanical properties of rat femora: interferences concerning mechanical regulation of bone modelling. J Bone Miner 1993, 8, 1389-1396.
8. Kowalik S., Valverde Piedra J.L., Pierzynowski S.G., Studzinski T.: The influence of alpha-ketoglutarate on growth, development and mineralisation of the skeletal system during the postnatal life in the pig. Acta Orthoped Scand 2002, Suppl. 304, 73, 50.
9. Neu J., Shenoy V., Chakrabarti R.: Glutamine nutrition and metabolism: where do we go from here? FASEB J 1996, 10, 829-837.
10. Pawłowska M., Kowalik S., Smyk M., Dec A., Szymańczyk S.E., Valverde Piedra J.L., Studziński T.: Wpływ L-alanylo-L-glutaminy na cechy wytrzymałościowe kości kończyn prosia̧t w okresie postnatalnym. Przegla̧d Hod 2001, 2, 38-40.
11. Pierzynowski S.G., Valverde Piedra J.L., Hommel-Hansen T., Studziński T.: Glutamine's importance in gut health. Int. J Feed Nutr Tech Feed Mix 2002, 10, 26-28.
12. Pierzynowski S.G., Sjodin A.: Perspectives of glutamine and its derivatives as feed additives for farm animals. J Anim Feed Sci 1998, 7, 79-91.
13. Puzio I., Kapica M., Bieńko M., Valverde Piedra J.L., Gajewski J., Wilczak Z., Kulasek G., Zabielski R.: Dietary bioactive substances influenced perinatal bone development in piglets. Livest Sci (2007), doi:10.1016/j.livsci. 2007.01.047
14. Reeds P.J., Burrin D.G., Jahoor F., Wykes L., Henry J., Frazer E.M.: Enterai glutamate is almost completely metabolized in first pass by the gastrointestinal tract of infant piglets. Am J Physiol 1996, 270, E413-E418.
15. Skrzypek T., Valverde Piedra J.L., Skrzypek H., Kazimierczak W., Szymańczyk S., Pawlowska M., Zabielski R: Intestinal villi structure during the development of pig and wild boar crossbreed neonates. Livest. Sci. (2007), doi:10.1016/j.livsci.2007.01.040
16. Ziegler T.R., Estívariz C.F., Jonas C.R., Gu L.H., Jones D.P., Leader L.M.: Interactions between nutrients and peptide growth factors in intestinal growth, repair, and function. J Parenter Enteral Nutr 1999, 23, S174-S183.