PPARγ activation abolishes LDL-induced proliferation of human aortic smooth muscle cells via SOD-mediated down-regulation of superoxide

Biochemical and Biophysical Research Communications

Volumn 359, Issue 4, 2007, Pages 1017-1023

  Heo, Kyung Sun ^a,b   Kim, Dong Uk ^a   Ryoo, Sungwoo ^a   Nam, Miyoung ^a   Baek, Seung Tae ^a   Kim, Lila ^a   Park, Song Kyu ^a   Myung, Chang Seon ^b   Hoe, Kwang Lae ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

Atherosclerosis; Low density lipoproteins; MAP kinase; PPAR; Smooth muscle cell; Superoxide; Troglitazone

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN E; HYDROGEN PEROXIDE; LOW DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P21; SUPEROXIDE; TROGLITAZONE; SUPEROXIDE DISMUTASE;

AORTA MEDIA; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE;

CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HUMANS; LIPOPROTEINS, LDL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PPAR GAMMA; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 34250675689     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.06.006     Document Type: Article

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