Tumor necrosis factor-α - 308 Polymorphism and leg ulceration - Possible association with obesity [1]

Journal of Investigative Dermatology

Volumn 127, Issue 7, 2007, Pages 1768-1769

  Nagy, Nikoletta ^a   Szolnoky, Gyõzõ ^a   Szabad, Gábor ^a   Bata Csörgõ, Zsuzsanna ^a   Balogh, Attila ^a   Klausz, Gergely ^a   Mándi, Yvette ^a   Dobozy, Attila ^a   Kemény, Lajos ^a   Széll, Márta ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

BLOOD CLOTTING; DISEASE ASSOCIATION; GENETIC POLYMORPHISM; HUMAN; INSULIN RESISTANCE; LEG ULCER; LETTER; LIPID METABOLISM; OBESITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; WOUND HEALING;

BODY MASS INDEX; CASE-CONTROL STUDIES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HUNGARY; LEG ULCER; LOGISTIC MODELS; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34250666620     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700769     Document Type: Letter

References (9)

1. Babbar N, Hacker A, Huang Y, Casero RA (2006) Tumor necrosis factor alpha induces spermidine/spermine N1-acetyltransferase (SSAT) through nuclear factor kappa B in non small cell lung cancer cells. J Biol Chem 281:24182-92
2. Brand E, Schorr U, Kunz I, Kertmen E, Ringel J, Distler A et al. (2001) Tumor necrosis factor-alpha - 308 G/A polymorphism in obese Caucasians. Int J Obes Relat Metab Disord 25:581-5
3. Cancello R, Tounian A, Poitou CH, Clement K (2004) Adiposity signals, genetic and body weight regulation in humans. Diabetes Metab 30:215-27
4. Crist SA, Elzey BD, Ludwig AT, Griffith TS, Staack JB, Lentz SR et al. (2004) Expression of TNF-related apoptosis-inducing ligand (TRAIL) in megakaryocytes and platelets. Exp Hematol 32:1073-81
5. Hoffstedt J, Eriksson P, Hellstrom L, Rossner S, Ryden M, Arner P (2000) Excessive fat accumulation is associated with the TNF alpha-308 G/A promoter polymorphism in women but not in men. Diabetologia 43:117-20
6. Nagy N, Szolnoky G, Szabad G, Bata-Csorgo Z, Dobozy A, Kemeny L et al. (2005) Single nucleotide polymorphisms of the fibroblast growth factor receptor 2 gene in patients with chronic venous insufficiency with leg ulcer. J Invest Dermatol 124:1085-8
7. Wallace HJ, Stacey MC (1998) Levels of tumor necrosis factor-alpha (TNF-α) and soluble TNF receptors in chronic venous leg ulcers - correlations to healing status. J Invest Dermatol 110:292-6
8. Wallace HJ, Vandongen YK, Stacey MC (2006) Tumor necrosis factor-alpha gene polymorphism associated with increased susceptibility to venous leg ulceration. J Invest Dermatol 126:921-5
9. Walston J, Seibert M, Yen CJ, Cheskin LJ, Andersen RE (1999) Tumor necrosis factor-alpha-238 and -308 polymorphisms do not associate with traits related to obesity and insulin resistance. Diabetes 48:2096-8