The in-vivo antimalarial activities of Uvaria chamae and Hippocratea africana

Annals of Tropical Medicine and Parasitology

Volumn 100, Issue 7, 2006, Pages 585-590

  Okokon, J E ^a   Ita, B N ^a   Udokpoh, A E ^a  

^a UNIVERSITY OF UYO   (Nigeria)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; HIPPOCRATEA AFRICANA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; UVARIA CHAMAE EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; FEMALE; HIPPOCRATEA AFRICANA; HIPPOCRATEACEAE; LD 50; MALARIA; MALE; MOUSE; NONHUMAN; PHYTOCHEMISTRY; PLANT ROOT; PLASMODIUM BERGHEI; SINGLE DRUG DOSE; SURVIVAL TIME; UVARIA; UVARIA CHAMAE; AFRICAN MEDICINE; ANIMAL; DRUG EFFECT; METHODOLOGY; ORAL DRUG ADMINISTRATION; PHYTOTHERAPY;

ANNONACEAE; CELASTRACEAE; HIPPOCRATEA; MUS; PLASMODIUM BERGHEI; UVARIA CHAMAE;

ADMINISTRATION, ORAL; ANIMALS; ANTIMALARIALS; FEMALE; HIPPOCRATEACEAE; MALARIA; MALE; MEDICINE, AFRICAN TRADITIONAL; MICE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; PLASMODIUM BERGHEI; UVARIA;

EID: 34250665446     PISSN: 00034983     EISSN: None     Source Type: Journal    
DOI: 10.1179/136485906X118512     Document Type: Article

References (18)

1. Addae-Kyereme, J., Croft, S. L., Kendrick, H. & Wright, C. W. (2001). Antiplasmodial activities of some Ghananian plants traditionally used for fever/ malaria treatment and of some alkaloids isolated from Pleicarpa mutica; in vivo antimalarial activity of pleicarpine. Journal of Ethnopharmacology, 76, 99-103.
2. Alanis, A. D., Calzada, F., Cervantes, J. A., Torres, J. & Ceballos, G. M. (2005). Antibacterial properties of some plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders. Journal of Ethnopharmacology, 100, 153-157.
3. Calzada, F. & Mata, R. (1995). Hippocrataine III, a sesquiterpine alkaloid from Hippocratea excelsa. Phytochemistry, 40, 583-585.
4. Calzada, F., Mata, R., Lopez, R., Linares, E., Bye, R., Barreto,V. M. & del Rio, F. (1991). Friedalanes and triterpenoid quinone methides from Hippocratea excelsa. Planta Medica, 57, 194-195.
5. Christensen, S. B. & Kharazmi, A. (2001). Antimalarial natural products. Isolation, characterization and biological properties. In Bioactive Compounds from Natural Sources: Isolation, Characterization and Biological Properties, ed. Tringali, C. pp. 379-432. London: Taylor & Francis.
6. Ebi, G. C., Ifeanacho , C. J. & Kamalu, T. N. (1999). Antimicrobial properties of Uvaria chamae. Fitoterapia, 70, 621-624.
7. Fall, D., Duval, R. A., Gleye, C., Laurens, A. & Hocque-Miller, K. (2004). Chamuvavinin, an acetogenin bearing tetrahydropyran ring from the root of Uvaria chamae. Journal of Natural Products, 67, 1041-1043.
8. Furukawa, M., Makino, M., Uchiyama, T., Ishimi, K., Ichinhe, Y. & Fujimoto, Y. (2002). Sesquiterpene pyridine alkaloids from Hippocratea excelsa. Phytochemistry, 59, 767-777.
9. Harbone, J. B. (1983). Phytochemical Methods: a Guide to Modern Techniques of Plant Analysis. London: Chapman & Hall.
10. Hutchinson, T. & Daziel, J. M. (1963). Flora of West Tropical Africa, Volume 2. London: Crown Agents for Overseas Government.
11. Knight, D. J. & Peters, W. (1980). The antimalarial action of N-benzyloxydihydrotriazines. 1. The action of clociguanil (BRL 50216) against rodent malaria, and studies on its mode of action. Annals of Tropical Medicine and Parasitology, 74, 393-404.
12. Lorke, D. (1983). A new approach to practical acute toxicity testing. Archives of Toxicology, 54, 275-286.
13. Ogunbona, F. A., Akata, K. J., Fadiran, E. O. & Femi-Oyewo, M. N. (eds) (1990). Malaria Chemotherapy in Nigeria: Problems and Prospects. Ibadan, Nigeria: University of Ibadan Press.
14. Perez, R. M., Zavala, M. A. & Salazar, M. (1995). Antiinflammatory activity of the bark of Hippocratea excelsa. Journal of Ethnopharmacology, 47, 85-90.
15. Philipov, S., Ivanovska, N., Istatkova, R., Velikova, M. & Tuleva, P. (2000). Phytochemical study and cytotoxic activity of alkaloids from Uvaria chamae P. Beauv. Die Pharmazie, 55, 688-689.
16. Philipson, J. D. & Wright, C. W. (1991). Antiprotozoal compounds from plant sources. Planta Medica, 57, 553-559.
17. Ryley, J. F. & Peters, W. (1970). The antimalarial activity of some quinone esters. Annals of Tropical Medicine and Parasitology, 84, 209-222.
18. Trease, A. & Evans, W. C. (1989). Trease and Evans' Pharmacognosy, 13th Edn. London: Baillière Tindall.