Changes of Wnt-3 protein during the proliferation of endogenous neural stem cells in neonatal rats with hypoxic-ischemic brain damage after hyperbaric oxygen therapy

Chinese Journal of Contemporary Pediatrics

Volumn 9, Issue 3, 2007, Pages 241-246

  Wang, Xiao Li ^a   Yang, Yu Jia ^a   Wang, Qing Hong ^a   Xie, Min ^a   Yu, Xiao He ^a   Liu, Chen Tao ^a   Wang, Xia ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Hyperbaric oxygen; Hypoxic ischemic brain damage; Neonatal rats; Neural stem cell; Wnt 3

Indexed keywords

BROXURIDINE; NESTIN; OXYGEN; WNT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CAROTID ARTERY LIGATION; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HEMISPHERE; HYPERBARIC OXYGEN; IMMUNOFLUORESCENCE; LASER MICROSCOPY; NEURAL STEM CELL; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; RAT; SPRAGUE DAWLEY RAT; SUBVENTRICULAR ZONE; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; BROMODEOXYURIDINE; CELL PROLIFERATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HYPERBARIC OXYGENATION; HYPOXIA-ISCHEMIA, BRAIN; INTERMEDIATE FILAMENT PROTEINS; MALE; NERVE TISSUE PROTEINS; NEURONS; RATS; STEM CELLS; WNT PROTEINS;

EID: 34250654903     PISSN: 10088830     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Triulzi F, Parazzini C, Righini A. Patterns of damage in the mature neonatal brain [J]. Pediatr Radiol, 2006, 36(7): 608-620.
2. Badr AE, Yin W, Mychaskiw G, Zhang JH. Dual effect of HBO on cerebral infarction in MCAO rats [J]. Am J Physiol Regul Integr Comp Physiol, 2001, 280(3): 766-770.
3. Calvert JW, Zhou C, Nanda A, Zhang JH. Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model [J]. J Appl Physiol, 2004, 95(5): 2072-2080.
4. Veltkamp R, Siebing DA, Heiland S, Schoenffeldt-Varas P, Veltkamp C, Schwaninger M, et al. Hyperbaric oxygen induces rapid protection against cerebral ischemia [J]. Brain Res, 2005, 1037 (1-2): 134-138.
5. Chinese source.
6. Chinese source.
7. Chinese source.
8. Leker RR, McKay RD. Using endogenous neural stem cells to enhance recovery from ischemic brain injury [J]. Curr Neurovasc, 2004, 1(5): 421-427.
9. Hayashi T, Iwai M., Ikeda T, Jin G, Deguchi K, Nagotani S, et al. Neural precursor cells division and migration in neonatal rat brain after ischemic/hypoxic injury [J]. Brain Res, 2005, 1038 (1): 41-49.
10. Felling RJ, Snyder MJ, Romanko MJ, Rothstein RP, Ziegler AN, Yang Z, et al. Neural stem/progenitor cells participate in the regenerative response to perinatal hypoxia/ischemia [J]. J Neurosci, 2006, 26(16): 4359-4369.
11. Inoue T, Kagawa T, Fukushima M, Shimizu T, Yoshinaga Y, Takada S, et al. Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin [J]. Stem Cells, 2006, 24 (1): 95-104.
12. Hirabayashi Y, Gotoh Y. Stage-dependent fate determination of neural precursor cells in mouse forebrain [J]. Neurosci Res, 2005, 51(4): 331-336.
13. Roelink H, Nusse R. Expression of two members of the Wnt family during mouse development - restricted temporal and spatial patterns in the developing neural tube [J]. Genes Dev, 1991, 5 (3): 381-388.
14. Lie DC, Colamarino SA, Song HJ, Desire L, Mira H, Consiglio A, et al. Wnt signalling regulates adult hippocampal neurogenesis [J]. Nature, 2005, 437(7063): 1370-1375.
15. Rice JE, Vannucci RC, Brierley JB. The influence of immaturity on hypoxic-ischemic brain damage in the rat [J]. Ann Neurol, 1981, 9 (2): 131-141.
16. Roelink H, Genaar E, Silva SLD, Nusse AR. Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain [J]. Proc Natl Acad Sci, 1990 (87): 4519-4523.
17. Gage FH. Mammalian neural stem cells [J]. Science, 2000, 287 (5457): 1433-1438.
18. Romanko MJ, Rothstein RP, Levison SW. Neural stem cells in the subventricular zone are resilient to hypoxia/ischemia whereas progenitors are vulnerable [J]. J Cereb Blood Flow Metab, 2004, 24 (7): 814-825.
19. Kikuchi A, Kishida S, Yamamoto H. Regulation of Wnt signaling by protein-protein interaction and post-translational modifications [J]. Experiment Molecul Med, 2006, 38(1): 1-10.
20. Miller RH. The promise of stem cells for neural repair [J]. Brain Res, 2006, 1091(1): 258-264.