Mathematical model of excitation-contraction in a uterine smooth muscle cell

American Journal of Physiology - Cell Physiology

Volumn 292, Issue 5, 2007, Pages

  Bursztyn, Limor ^a   Eytan, Osnat ^b   Jaffa, Ariel J ^a,b   Elad, David ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b LIS MATERNITY HOSPITAL   (Israel)

Author keywords

Cellular calcium control mechanisms; Myometrial contractions; Myosin light chain phosphorylation

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; CALCIUM CHANNEL; MYOSIN LIGHT CHAIN; SODIUM CALCIUM EXCHANGE PROTEIN;

ACTIN FILAMENT; ARTICLE; CALCIUM CELL LEVEL; CELL MEMBRANE; DEPOLARIZATION; MATHEMATICAL MODEL; MUSCLE CONTRACTION; MUSCLE EXCITATION; MYOMETRIUM; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; STRESS; VOLTAGE CLAMP; ANIMAL; BIOLOGICAL MODEL; CALCIUM SIGNALING; CELL MEMBRANE POTENTIAL; COMPARATIVE STUDY; COMPUTER SIMULATION; CYTOLOGY; FEMALE; HUMAN; METABOLISM; MUSCLE RELAXATION; PATCH CLAMP; PHOSPHORYLATION; PHYSIOLOGY; RAT; THEORETICAL MODEL; TIME; UTERUS CONTRACTION;

RATTUS;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; COMPUTER SIMULATION; FEMALE; HUMANS; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; MODELS, THEORETICAL; MUSCLE RELAXATION; MYOCYTES, SMOOTH MUSCLE; MYOMETRIUM; MYOSIN LIGHT CHAINS; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; RATS; SODIUM-CALCIUM EXCHANGER; TIME FACTORS; UTERINE CONTRACTION;

EID: 34250651272     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00478.2006     Document Type: Article

References (37)

1. 2+/calmodulin-dependent protein kinase II in vascular smooth muscle cells. J Biol Chem 271: 2506-2513, 1996.
2. Andersen HF, Barclay ML. A computer model of uterine contractions based on discrete contractile elements. Obstet Gynecol 86: 108-111, 1995.
3. Eytan O, Elad D. Analysis of intra-uterine fluid motion induced by uterine contractions. Bull Math Biol 61: 221-238, 1999.
4. Grover AK, Kwan CY, Rangachari PK, Daniel EE. Na-Ca exchange in a smooth muscle plasma membrane-enriched fraction. Am J Physiol Cell Physiol 244: C158-C165, 1983.
5. Hai CM, Murphy RA. Cross-bridge phosphorylation and regulation of latch state in smooth muscle. Am J Physiol Cell Physiol 254: C99-C106, 1988.
6. 2+/calmodulin-dependent protein kinase II. Biochem J 364: 593-611, 2002.
7. Inoue Y, Nakao K, Okabe K, Izumi H, Kanda S, Kitamura K, Kuriyama H. Some electrical properties of human pregnant myometrium. Am J Obstet Gynecol 162: 1090-1098, 1990.
8. Keener J, Sneyd J. Mathematical Physiology. New York: Springer, 1998, p. 51-53, 161-187.
9. Kuriyama H, Kitamura K, Itoh T, Inoue R. Physiological features of visceral smooth muscle cells, with special reference to receptors and ion channels. Physiol Rev 78: 811-920, 1998.
10. 2+ transport in myometrium. In: Control of Uterine Contractility, edited by Garfield RE, Tabb TN. Boca Raton, FL: CRC, 1993.
11. Leyendecker G, Kunz G, Herbertz M, Beil D, Huppert P, Mall G, Kissler S, Noe M, Wildt L. Uterine peristaltic activity and the development of endometriosis. Ann NY Acad Sci 1034: 338-355, 2004.
12. Mackenzie LW, Word RA, Casey ML, Stull JT. Myosin light chain phosphorylation in human myometrial smooth muscle cells. Am J Physiol Cell Physiol 258: C92-C98, 1990.
13. Parkington HC, Coleman HA. Excitability in uterine smooth muscle. Front Horm Res 27: 179-200, 2001.
14. + pump. J Physiol 514: 229-243, 1999.
15. 2+ oscillators. Am J Physiol Heart Circ Physiol 277: H1119-H1144, 1999.
16. Reynolds SR. Uterine growth during pregnancy, In: Physiology of the Uterus. London: Hamish Hamilton Medical Books, 1939.
17. Sanborn BM. Relationship of ion channel activity to control of myometrial calcium. J Soc Gynecol Investig 7: 4-11, 2000.
18. i transients in single smooth muscle cells isolated from pregnant rat uterus. J Physiol 511: 803-811, 1998.
19. i transient in uterine smooth muscle cells isolated from pregnant rats. Pflügers Arch 437: 158-160, 1998.
20. 2+ measurements in rat uterine myocytes. Cell Calcium 37: 215-223, 2005.
21. Sneyd J, Keizer J, Sanderson MJ. Mechanisms of calcium oscillations and waves: a quantitative analysis. FASEB J 9: 1463-1472, 1995.
22. i signaling in pregnant human myometrium. Am J Physiol Endocrinol Metab 267: E77-E87, 1994.
23. 2+ sensitivity of light chain phosphorylation within smooth muscle cells. J Biol Chem 269: 9912-9920, 1994.
24. Tansey MG, Word RA, Hidaka H, Singer HA, Schworer CM, Kamm KE, Stull JT. Phosphorylation of myosin light chain kinase by the multifunctional calmodulin-dependent protein kinase II in smooth muscle cells. J Biol Chem 267: 12511-12516, 1992.
25. 2+ is a primary determinant for myosin phosphorylation in smooth muscle cells. J Biol Chem 264: 6207-6213, 1989.
26. Taylor DA, Stull JT. Calcium dependence of myosin light chain phosphorylation in smooth muscle cells. J Biol Chem 263: 14456-14462, 1988.
27. Vauge C, Mignot TM, Paris B, Breuiller-Fouche M, Chapron C, Attoui M, Ferre F. A mathematical model for the spontaneous contractions of the isolated uterine smooth muscle from patients receiving progestin treatment. Acta Biotheor 51: 19-34, 2003.
28. Wildt L, Kissler S, Licht P, Becker W. Sperm transport in the human female genital tract and its modulation by oxytocin as assessed by hysterosalpingoscintigraphy, hysterotonography, electrohysterography and Doppler sonography. Hum Reprod Update 4: 655-666, 1998.
29. Word RA, Stull JT, Casey ML, Kamm KE. Contractile elements and myosin light chain phosphorylation in myometrial tissue from nonpregnant and pregnant women. J Clin Invest 92: 29-37, 1993.
30. Word RA, Tang DC, Kamm KE. Activation properties of myosin light chain kinase during contraction/relaxation cycles of tonic and phasic smooth muscles. J Biol Chem 269: 21596-21602, 1994.
31. Wray S, Kupittayanant S, Shmygol A, Smith RD, Burdyga T. The physiological basis of uterine contractility: a short review. Exp Physiol 86: 239-246, 2001.
32. Wray S, Jones K, Kupittayanant S, Li Y, Matthew A, Monir-Bishty E, Noble K, Pierce SJ, Quenby S, Shmygol AV. Calcium signaling and uterine contractility. J Soc Gynecol Investig 10: 252-264, 2003.
33. Yang J, Clark JW Jr, Bryan RM, Robertson CS. The myogenic response in isolated rat cerebrovascular arteries: smooth muscle cell model. Med Eng Phys 25: 691-709, 2003.
34. Yoshino M, Wang SY, Kao CY. Sodium and calcium inward currents in freshly dissociated smooth myocytes of rat uterus. J Gen Physiol 110: 565-577, 1997.
35. Young RC. A computer model of uterine contractions based on action potential propagation and intercellular calcium waves. Obstet Gynecol 89: 604-608, 1997.
36. Young RC, Schumann R, Zhang P. Intracellular calcium gradients in cultured human uterine smooth muscle: a functionally important subplasmalemmal space. Cell Calcium 29: 183-189, 2001.
37. Young RC, Smith LH, Anderson NC Jr. Passive membrane properties and inward calcium current of human uterine smooth muscle cells. Am J Obstet Gynecol 164: 1132-1139, 1991.