Quantitative LC/MS/MS method and pharmacokinetic studies of columbin, an anti-inflammation furanoditerpen isolated from Radix Tinosporae

Biomedical Chromatography

Volumn 21, Issue 6, 2007, Pages 642-648

  Shi, Qirong ^a   Liang, Mingjin ^a   Zhang, Weidong ^a,b   Zhang, Chuan ^a   Liu, Runhui ^a   Shen, Yunheng ^a   Li, Huiliang ^b   Wang, Xiaolin ^c   Wang, Xiangwei ^c   Pan, Qiongqun ^c   Chen, Chunlin ^c  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c Shanghai Medicilon Inc   (China)

Author keywords

Bioavailability; Columbin; HPLC MS MS; Pharmacokinetics

Indexed keywords

ENZYME ACTIVITY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PATHOLOGY; PHARMACOKINETICS; RATS;

ANTI-INFLAMMATION; ANTI-TUMORS; BIOAVAILABILITY; COLUMBIN; HPLC-MS-MS; IN-VIVO; LC-MS-MS; ORAL BIOAVAILABILITIES; PHARMACOKINETIC STUDIES; PHARMACOLOGICAL ACTIVITY;

METHANOL;

ANTIINFLAMMATORY AGENT; COLUMBIN; PLANT EXTRACT; TERT BUTYL METHYL ETHER; TINOSPORA SAGITTATA EXTRACT; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CALIBRATION; CORRELATION COEFFICIENT; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; ENZYME INHIBITION; FIRST PASS EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MEDICINAL PLANT; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; TINOSPORA; TINOSPORA SAGITTATA;

RATTUS;

EID: 34250642774     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.802     Document Type: Article

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