Is cognitive dysfunction a complication of adjuvant chemotherapy in the older patient with breast cancer?

Breast Cancer Research and Treatment

Volumn 103, Issue 3, 2007, Pages 259-268

  Hurria, Arti ^a   Lachs, Mark ^b  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Adjuvant chemotherapy; Breast cancer; Cognitive function; Geriatric; Memory; Neuropsychological; Older adult

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; METHOTREXATE; PACLITAXEL; TAMOXIFEN; TRASTUZUMAB;

ADJUVANT THERAPY; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER RISK; CLINICAL ASSESSMENT; COGNITION; COGNITIVE DEFECT; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; DRUG DOSE INCREASE; DRUG MEGADOSE; HUMAN; METHODOLOGY; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; REVIEW; TREATMENT DURATION; TREATMENT PLANNING;

ADULT; AGED; AGING; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; COGNITION; COGNITION DISORDERS; FEMALE; GERIATRICS; HUMANS; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS;

EID: 34250639945     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-006-9383-9     Document Type: Review

References (20)

1. Wefel JS, Lenzi R, Theriault RL, Davis RN, Meyers CA (2004) The cognitive sequelae of standard-dose adjuvant chemotherapy in women with breast carcinoma: results of a prospective, randomized, longitudinal trial. Cancer 100:2292-2299
2. Weineke MH, Dienst E (1995) Neuropsychological assessment of cognitive functioning following chemotherapy for breast cancer. Psycho-Oncology 4:61-66
3. Brezden CB, Phillips K, Abdolell M, Bunston T et al (2000) Cognitive function in breast cancer patients receiving adjuvant chemotherapy. J Clin Oncol 18(14):2695-2701
4. Schagen SB, Van Dam F, Muller MJ et al (1999) Cognitive deficits after postoperative adjuvant chemotherapy for breast carcinoma. Cancer 85(3):640-650
5. Van Dam FSAM, Schagen SB, Muller MJ et al (1998) Impairment of cognitive function in women receiving adjuvant treatment for high-risk breast cancer: high dose versus standard dose chemotherapy. J Natl Cancer Inst 90(3):210-218
6. Schagen SB, Muller MJ, Boogerd W, Rosenbrand RM, van Rhijn D, Rodenhuis S, van Dam FS (2002) Late effects of adjuvant chemotherapy on cognitive function: a follow-up study in breast cancer patients. Ann Oncol 13(9):1387-1397
7. Ahles TA, Saykin AJ, Furstenberg CT, Cole B, Matt LA, Skalla K, Whedon MB, Bivens S, Mitchell T, Greenberg ER, Silberfarb PM (2002) Neuropsychologic impact of standard-dose systemic chemotherapy in long-term survivors of breast cancer and lymphoma. J Clin Oncol 20:485-493
8. Castellon SA, Ganz PA, Bower JE, Petersen L, Abraham L, Greendale GA (2004) Neurocognitive performance in breast cancer survivors exposed to adjuvant chemotherapy and tamoxifen. J Clin Exp Neuropsychol 26(7):955-969
9. Tchen N, Juffs HG, Downie FP, Yi Q, Hu H, Chemerynsky I, Clemons M, Crump M, Gross PE, Warr D, Tweedale ME, Tannock I (2003) Cognitive function, fatigue, and menopausal symptoms in women receiving adjuvant chemotherapy for breast cancer. J Clin Oncol 21:4175-4183
10. Hurria A, Rosen C, Hudis C, Zuckerman E, Panageas K, Lachs MS, Witmer M, van Gorp W, Fornier M, D'Andrea G, Moasser M, Dang C, VanPoznak C, Currie V, Theodoulou M, Robson M, Hurria A, Pearce C, Norton L, Holland J (2006) Effect of adjuvant chemotherapy on the cognitive function of older patients with breast cancer. J Am Geriatr Soc 54(6):925-931
11. Wilkinson GS (1993) The Wide Range Achievement Test, Revised (WRAT-3). Wide Range, Wilmington
12. Kaplan EF, Goodglass H, Weintraub S (1983) The Boston Naming Test, 2nd edn. Lea & Febiger, Philadelphia
13. Benton AL, Hamscher K de S (1989) Multilingual Aphasia Examination. AJA Associates, Iowa City
14. Bennedict RHB, Schretlen D, Groninger L, Brandt J (1998) Hopkins Verbal Learning Test-Revised: normative data and analysis of inter-form and test-retest reliability. Clin Neuropsychol 12:43-55
15. Meyers J, Meyers K (1996) The Meyers scoring system for the Rey complex figure and the recognition trial: professional manual. Psychological Assessment Resources, Odessa
16. Rey A (1941) L'examen psychologique dans les cas d'encephalopathie traumatique. Arch Psychol 28:286-340
17. Osterrieth PA (1944) Le test de copie d'une figure complexe. Arch Psychol 30:206-356
18. Wechsler D (1997) Wechsler Adult Intelligence Scale, 3rd edn. (WAIS-III). Harcourt Brace & Co., San Antonio
19. Reitan RM (1958) The validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills 8:271-276
20. Golden CJ (1978) Stroop Color and Word Test. Stoelting, Chicago