Transient elevation of serum tumor markers in a patient with hypothyroidism

American Journal of the Medical Sciences

Volumn 333, Issue 6, 2007, Pages 387-389

  Takahashi, Nobuyuki ^a   Shimada, Toshio ^a   Ishibashi, Yutaka ^a   Oyake, Nobuyuki ^a   Murakami, Yo ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

Hormone treatment; Hypothyroidism; Tumor markers

Indexed keywords

CA 125 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; GALLIUM; LEVOTHYROXINE; THYROTROPIN; THYROXINE; TUMOR MARKER;

ABDOMINAL RADIOGRAPHY; AGED; ANALYTICAL PARAMETERS; ANEMIA; ANTIGEN DETECTION; ARTICLE; ASCITES; BLOOD CHEMISTRY; CASE REPORT; CLINICAL EXAMINATION; COMPUTER ASSISTED TOMOGRAPHY; CONCENTRATION (PARAMETERS); DIAGNOSTIC IMAGING; ELECTROCARDIOGRAPHY; FEMALE; FREE THYROXINE INDEX; HEART LEFT VENTRICLE HYPERTROPHY; HORMONE SUBSTITUTION; HOSPITAL ADMISSION; HUMAN; HYPOTHYROIDISM; PERICARDIAL EFFUSION; PLEURA EFFUSION; RECTUM PROLAPSE; SCINTIGRAPHY; THORAX RADIOGRAPHY; THYROID FUNCTION TEST; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TRANSVAGINAL ECHOGRAPHY; TREATMENT OUTCOME; UTERUS PROLAPSE;

AGED; CA-125 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; HYPOTHYROIDISM; THYROTROPIN; THYROXINE; TUMOR MARKERS, BIOLOGICAL;

EID: 34250636311     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e318065b023     Document Type: Article

References (20)

1. Roberts CG, Ladenson PW. Hypothyroidism. Lancet 2004;363:793-803.
2. Gold P, Freedman SO. Specific carcinoembryonic antigens of the human digestive system. J Exp Med 1965;122:467-81.
3. Amino N, Kuro R, Yabu Y, et al. Elevated levels of circulating carcinoembryonic antigen in hypothyroidism. J Clin Endocrinol Metab 1981;52:457-62.
4. Kawashima M, Amino N, Kuro R, et al. Increase of serum carcinoembryonic antigen in hypothyroidism. Rinsho Byori 1982;30:903-6.
5. Hashimoto T, Matsubara F. Changes in the tumor marker concentration in female patients with hyper-, eu- and hypothyroidism. Endocrinol Jpn 1989;36:873-9.
6. van Mil AH, Beijer C, Jonkers GJ. High levels of carcinoembryonic antigen in a woman with hypothyroidism. Ned Tijdschr Geneeskd 2001;145:1071-4.
7. Bertola G, Balza G, Oriani A, et al. Elevated concentration of serum carcinoembryonic antigen in hypothyroidism. Recent Prog Med 2004;95:204-6.
8. Bast RC, Feeney M, Lazarus H, et al. Reactivity of a monoclonal antibody with human ovarian carcinoma. J Clin Invest 1981;68:1331-7.
9. Depczynski B, Ward R, Eisman J. The association between myxedematous ascites and extreme elevation of serum tumor markers. J Clin Endocrinol Metab 1996;81:4175.
10. Krishnan STM, Philipose Z, Rayman G. Hypothyroidism mimicking intra-abdominal malignancy. BMJ 2002;325:946-7.
11. Duarte DR, Chang CV, Minicucci MF, et al. Myxedema ascites with elevated serum CA125 concentration. Am J Med Sci 2006;331:103-4.
12. Shuster J, Silverman M, Gold P. Metabolism of human carcinoembryonic antigen in xenogeneic animals. Cancer Res 1973;33:65-8.
13. De Castro F, Bonacini M, Walden JM, et al. Myxoedema ascites: report of two cases and review of the literature. J Clin Gastroenterol 1991;13:411-4.
14. Sevinc A, Sari R, Camci C, et al. A secondary interpretations is needed on serum CA 125 levels in case of serosal involvement. J R Soc Health 2000;120:268-70.
15. Jager W, Meier C, Wildt L, et al. CA125 serum concentrations during the menstrual cycle. Fertil Steril 1988;50:223-7.
16. Scommegna A, Castillo E, Borushek S, et al. Factors in polycystic ovary development, II: role of the pituitary in the rat. Fertil Steril 1965;16:571-8.
17. Rotmensch S, Scommegna A. Spontaneous ovarian hyperstimulation syndrome associated with hypothyroidism. Am J Obstet Gynecol 1989;160:1220-2.
18. Dobozy O, Csaba G, Hetenyi G, et al. Investigation of gonadotropine-thyrotropin overlapping and hormonal imprinting in the rat testis. Acta Physiol Hung 1985;66:169-75.
19. Tekin O. Hypothyroidism-related CA 19-9 elevation. Mayo Clin Proc 2002;77:398.
20. Aguiar-Bujanda D, Bohn-Sarmiento U, Aguiar-Morales J. False elevation of serum CA 15-3 levels in patients under follow-up for breast cancer. Breast J 2004;10:375-6.