Pro-apoptotic activity of imidazole derivatives mediated by up-regulation of Bax and activation of CAD in Ehrlich Ascites Tumor cells

Investigational New Drugs

Volumn 25, Issue 4, 2007, Pages 343-350

  Anil Kumar, C ^a   Jayarama, Shankar ^a   Basappa, ^a   Salimath, Bharathi P ^a   Rangappa, Kanchugarakoppal S ^a  

^a UNIVERSITY OF MYSORE   (India)

Author keywords

Apoptosis; Bax cytochrome c and Bcl 2; Caspase 3; Caspase activated DNase; Imidazole derivatives

Indexed keywords

CAD PROTEIN; CASPASE 3; CYTOCHROME C; DNA FRAGMENT; IMIDAZOLE DERIVATIVE; LIPOCORTIN 5; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE PHASE; CELL DEATH; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; EHRLICH ASCITES TUMOR; ENZYME ACTIVITY; FEMALE; FLOW CYTOMETRY; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; STAINING; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, EHRLICH TUMOR; CASPASE 3; CYTOCHROMES C; DEOXYRIBONUCLEASES; DNA FRAGMENTATION; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; IMIDAZOLES; MICE; PROTEIN TRANSPORT; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 34250635910     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-006-9033-4     Document Type: Article

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