Blunted ventilatory response to hypoxia/hypercapnia in mice with cigarette smoke-induced emphysema

Respiratory Physiology and Neurobiology

Volumn 158, Issue 1, 2007, Pages 5-13

  Xu, F ^a   Zhuang, J ^a   Wang, R ^a   Seagrave, J C ^a   March, T H ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

COPD; Inflammation; Ventilatory responses

Indexed keywords

CARBON DIOXIDE; CIGARETTE SMOKE; NITROGEN;

AIR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL GAS; ARTICLE; BREATHING; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DYSPNEA; EMPHYSEMA; FEMALE; HYPERCAPNIA; HYPOTHESIS; HYPOXIA; LUNG MINUTE VOLUME; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOPHYSIOLOGY; PNEUMONIA; PRIORITY JOURNAL; PROVOCATION TEST; RESPIRATORY FUNCTION;

ANIMALS; ANOXIA; DISEASE MODELS, ANIMAL; EMPHYSEMA; FEMALE; HYPERCAPNIA; LUNG; MICE; MICE, INBRED C3H; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY TRACT DISEASES; SMOKE;

EID: 34250631377     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2007.04.004     Document Type: Article

References (46)

1. Altose M.D., McCauley W.C., Kelsen S.G., and Cherniack N.S. Effects of hypercapnia and inspiratory flow-resistive loading on respiratory activity in chronic airways obstruction. J. Clin. Invest. 59 (1977) 500-507
2. Anto J.M., Vermeire P., Vestbo J., and Sunyer J. Epidemiology of chronic obstructive pulmonary disease. Eur. Respir. J. 17 (2001) 982-994
3. Barnes P.J. Chronic obstructive pulmonary disease. N. Engl. J. Med. 343 (2000) 269-280
4. Bedell G.N., and Rosenberg R.S. Direct method for respiratory center evaluation in man. J. Appl. Physiol. 16 (1961) 928-933
5. Burrows B., and Earle R.H. Course and prognosis of chronic obstructive lung disease. A prospective study of 200 patients. N. Engl. J. Med. 280 (1969) 397-404
6. 2 in the newborn lamb. J. Physiol. 503 Pt 1 (1997) 187-194
7. Calverley P.M. Respiratory failure in chronic obstructive pulmonary disease. Eur. Respir. J. Suppl. 47 (2003) 26s-30s
8. 2 in the cat. J. Appl. Physiol. 75 (1993) 2383-2391
9. 2. J. Clin. Invest. 35 (1956) 1286-1290
10. Cohen B.H., Ball Jr. W.C., Bias W.B., Brashears S., Chase G.A., Diamond E.L., Hsu S.H., Kreiss P., Levy D.A., Menkes H.A., Permutt S., and Tockman M.S. A genetic-epidemiologic study of chronic obstructive pulmonary disease. I. Study design and preliminary observations. Johns Hopkins Med. J. 137 (1975) 95-104
11. Cohen B.H., Ball Jr. W.C., Brashears S., Diamond E.L., Kreiss P., Levy D.A., Menkes H.A., Permutt S., and Tockman M.S. Risk factors in chronic obstructive pulmonary disease (COPD). Am. J. Epidemiol. 105 (1977) 223-232
12. Cooper C.B., and Howard P. An analysis of sequential physiologic changes in hypoxic cor pulmonale during long-term oxygen therapy. Chest 100 (1991) 76-80
13. Daristotle L., Berssenbrugge A.D., and Bisgard G.E. Hypoxic-hypercapnic ventilatory interaction at the carotid body of awake goats. Respir. Physiol. 70 (1987) 63-72
14. Fahey P.J., and Hyde R.W. Won't breathe" vs "can't breathe" detection of depressed ventilatory drive in patients with obstructive pulmonary disease. Chest 84 (1983) 19-25
15. Franciosi L.G., Page C.P., Celli B.R., Cazzola M., Walker M.J., Danhof M., Rabe K.F., and Della Pasqua O.E. Markers of exacerbation severity in chronic obstructive pulmonary disease. Respir. Res. 7 (2006) 74
16. Goldring R.M., Turino G.M., and Heinemann H.O. Respiratory-renal adjustments in chronic hypercapnia in man. Extracellular bicarbonate concentration and the regulation of ventilation. Am. J. Med. 51 (1971) 772-784
17. Gorini M., Spinelli A., Ginanni R., Duranti R., Gigliotti F., and Scano G. Neural respiratory drive and neuromuscular coupling in patients with chronic obstructive pulmonary disease (COPD). Chest 98 (1990) 1179-1186
18. Guerassimov A., Hoshino Y., Takubo Y., Turcotte A., Yamamoto M., Ghezzo H., Triantafillopoulos A., Whittaker K., Hoidal J.R., and Cosio M.G. The development of emphysema in cigarette smoke-exposed mice is strain dependent. Am. J. Respir. Crit. Care Med. 170 (2004) 974-980
19. Khilnani G.C., Banga A., and Sharma S.K. Predictors of mortality of patients with acute respiratory failure secondary to chronic obstructive pulmonary disease admitted to an intensive care unit: a one year study. BMC Pulm. Med. 4 (2004) 12
20. Mahadeva R., and Shapiro S.D. Chronic obstructive pulmonary disease. 3. Experimental animal models of pulmonary emphysema. Thorax 57 (2002) 908-914
21. March T.H., Barr E.B., Finch G.L., Hahn F.F., Hobbs C.H., Menache M.G., and Nikula K.J. Cigarette smoke exposure produces more evidence of emphysema in B6C3F1 mice than in F344 rats. Toxicol. Sci. 51 (1999) 289-299
22. March T.H., Bowen L.E., Finch G.L., Nikula K.J., Wayne B.J., and Hobbs C.H. Effects of strain and treatment with inhaled all-trans-retinoic acid on cigarette smoke-induced pulmonary emphysema in mice COPD. J. Chron. Obstruct. Pulmon. Dis. 2 (2005) 289-302
23. March T.H., and Seagrave J.C. Strain-specific pulmonary inflammatory responses and emphysema development in cigarette smoke-exposed mice. Toxicol. Pathol. 35 1 (2007) 183 (Abstract)
24. March T.H., Wilder J.A., Esparza D.C., Cossey P.Y., Blair L.F., Herrera L.K., McDonald J.D., Campen M.J., Mauderly J.L., and Seagrave J. Modulators of cigarette smoke-induced pulmonary emphysema in A/J mice. Toxicol. Sci. 92 (2006) 545-559
25. Marchand E., and Decramer M. Respiratory muscle function and drive in chronic obstructive pulmonary disease. Clin. Chest Med. 21 (2000) 679-692
26. C O2-VAS response slope in humans. Respir. Physiol. 126 (2001) 173-181
27. 2 response and hypercapnia in severe chronic obstructive pulmonary disease. Eur. Respir. J. 12 (1998) 666-671
28. Morrison N.J., Richardson J., Dunn L., and Pardy R.L. Respiratory muscle performance in normal elderly subjects and patients with COPD. Chest 95 (1989) 90-94
29. Ou L.C., and Tenney S.M. Hypoxia and carbon dioxide as separate and interactive depressants of ventilation. Respir. Physiol. 28 (1976) 347-358
30. Pauwels R., Calverley P., Buist A.S., Rennard S., Fukuchi Y., Stahl E., and Lofdahl C.G. COPD exacerbations: the importance of a standard definition. Respir. Med. 98 (2004) 99-107
31. Pauwels R.A., Buist A.S., Calverley P.M., Jenkins C.R., and Hurd S.S. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am. J. Respir. Crit. Care Med. 163 (2001) 1256-1276
32. 2 interaction in the rat carotid body in vitro. J. Physiol. 485 Pt 2 (1995) 531-541
33. 2. Pflugers Archiv. 251 (1949) 689-715
34. Siafakas N.M., and Tzortzaki E.G. Few smokers develop COPD why?. Respir. Med. 96 (2002) 615-624
35. Snider G.L. Experimental studies on emphysema and chronic bronchial injury. Eur. J. Respir. Dis. Suppl. 146 (1986) 17-35
36. Sorli J., Grassino A., Lorange G., and Milic-Emili J. Control of breathing in patients with chronic obstructive lung disease. Clin. Sci. Mol. Med. 54 (1978) 295-304
37. Sovik S., and Lossius K. Development of ventilatory response to transient hypercapnia and hypercapnic hypoxia in term infants. Pediatr. Res. 55 (2004) 302-309
38. Tankersley C.G., and Broman K.W. Interactions in hypoxic and hypercapnic breathing are genetically linked to mouse chromosomes 1 and 5. J. Appl. Physiol. 97 (2004) 77-84
39. Tankersley C.G., Fitzgerald R.S., and Kleeberger S.R. Differential control of ventilation among inbred strains of mice. Am. J. Physiol. 267 (1994) R1371-R1377
40. Tatsumi K., Kimura H., Kunitomo F., Kuriyama T., Watanabe S., and Honda Y. Sleep arterial oxygen desaturation and chemical control of breathing during wakefulness in COPD. Chest 90 (1986) 68-73
41. Topeli A., Laghi F., and Tobin M.J. The voluntary drive to breathe is not decreased in hypercapnic patients with severe COPD. Eur. Respir. J. 18 (2001) 53-60
42. Ucgun I., Metintas M., Moral H., Alatas F., Yildirim H., and Erginel S. Predictors of hospital outcome and intubation in COPD patients admitted to the respiratory ICU for acute hypercapnic respiratory failure. Respir. Med. 100 (2006) 66-74
43. van de Ven M.J., Colier W.N., van der Sluijs M.C., Oeseburg B., Vis P., and Folgering H. Effects of acetazolamide and furosemide on ventilation and cerebral blood volume in normocapnic and hypercapnic patients with COPD. Chest 121 (2002) 383-392
44. Verbeken E.K., Cauberghs M., Mertens I., Clement J., Lauweryns J.M., and Van de Woestijne K.P. The senile lung. Comparison with normal and emphysematous lungs. 2. Functional aspects. Chest 101 (1992) 800-809
45. Wang R., and Xu F. Postnatal development of right atrial injection of capsaicin-induced apneic response in rats. J. Appl. Physiol. 101 (2006) 60-67
46. 2 in newborn piglets. J. Physiol. 456 (1992) 39-48