Increased laryngeal lavage lipid-laden macrophage index during acute bronchiolitis

Acta Paediatrica, International Journal of Paediatrics

Volumn 96, Issue 7, 2007, Pages 1025-1029

  Kim, Chang Keun ^a   Kim, Hyo Bin ^a   Kurian, Twinkle ^a   Chung, Ju Young ^a   Yoo, Young ^b   Koh, Young Yull ^c  

^a Inje University College of Medicine   (South Korea)

^b College of Medicine   (South Korea)

^c Seoul National University Hospital   (South Korea)

Author keywords

Aspiration; Bronchiolitis; Laryngeal lavage; Lipid laden macrophage index

Indexed keywords

ACUTE DISEASE; ANALYTICAL PARAMETERS; ARTICLE; ASPIRATION; BRONCHIOLITIS; CELL COUNT; CLINICAL ARTICLE; CLINICAL ASSESSMENT; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; INFANT; LARYNX; LAVAGE; LEUKOCYTE DIFFERENTIAL COUNT; LIPID ANALYSIS; LIPID LADEN MACROPHAGE INDEX; MALE; PH MEASUREMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; REMISSION; REPEAT PROCEDURE; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RISK ASSESSMENT; STATISTICAL SIGNIFICANCE;

ACUTE DISEASE; BIOLOGICAL MARKERS; BODY FLUIDS; BRONCHIOLITIS, VIRAL; FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; HYDROGEN-ION CONCENTRATION; INFANT; IRRIGATION; LARYNGOSCOPY; LARYNX; LIPIDS; MACROPHAGES, ALVEOLAR; MALE; NEUTROPHILS; RESPIRATORY ASPIRATION; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; SENSITIVITY AND SPECIFICITY;

EID: 34250628329     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2007.00314.x     Document Type: Article

References (28)

1. Khoshoo V, Edell D. Previously healthy infants may have increased risk of aspiration during respiratory syncytial viral bronchiolitis. Pediatrics 1999 104 : 1389 90.
2. Colombo JL, Hallberg TK. Airway reactivity following repeated milk aspiration in rabbits. Pediatr Pulmonol 2000 29 : 113 9.
3. Nussbaum E, Maggi JC, Mathis R, Galant SP. Association of lipid-laden alveolar macrophages and gastroesphageal reflux in children. J Pediatr 1987 110 : 190 4.
4. Kurlandsky Le, Vaandrager V, Davy C, Stockinger FS. Lipoid pneumonia in association with gastroesophageal reflux. Pediatr Pulmonol 1992 13 : 184 8.
5. Colombo JL, Hallberg TK. Recurrent aspiration in children: lipid laden alveolar macrophage quantitation. Pediatr Pulmonol 1987 3 : 86 9.
6. Cohen AB, Cline MJ. In vitro studies of the foamy macrophage of postobstructive endogenous lipoid pneumonia in man. Am Rev Respir Dis 1972 106 : 69 78.
7. Desai R, Tetley TD, Curtis CG, Powell GM, Richards RJ. Studies on the fate of pulmonary surfactant in the lung. Biochem J 1978 176 : 455 62.
8. Colombo JL. Pulmonary aspiration. In : Hilman BC, editor. Pediatric respiratory disease: diagnosis and treatment. Philadelphia : Saunders WB, 1993 : 429 36.
9. McVeagh P, Howman-Giles R, Kemp A. Pulmonary aspiration studied by radionuclide milk scanning and barium swallow roentgenography. Am J Dis Child 1987 141 : 917 21.
10. Corwin RW, Irwin RS. The lipid-laden alveolar macrophage as a marker of aspiration parenchymal lung disease. Am Rev Respir Dis 1985 132 : 576 81.
11. Bhandari B, Singh SV, Sharma VK. Bacteriological diagnosis of pulmonary tuberculosis. A comparative study of gastric wash, laryngeal swab and lung puncture. Indian J Pediatr 1971 38 : 349 53.
12. Lloyd AV. Bacteriological diagnosis of tuberculosis in children: a comparative study of gastric lavage and laryngeal swab methods. East Afr Med J 1968 45 : 140 3.
13. Everard ML. Acute bronchiolitis-a perennial problem [letter]. Lancet 1996 348 : 279 80.
14. Kaul A, Scott R, Gallagher M, Scott M, Clement J, Ogra PL. Respiratory syncytial virus infection: rapid diagnosis in children by use of indirect immunofluorescence. Am J Dis Child 1978 132 : 1088 90.
15. Herbst JJ, Book LS, Bry PF. Gastroesophageal reflux in the "near miss" sudden infant death syndrome. J Pediatr 1978 92 : 73 5.
16. Jansson L, Nilsson P, Olsson M. Socioeconomic environmental factors and hospitalization for acute bronchiolitis during infancy. Acta Paediatr 2002 91 : 335 8.
17. de Blic J, Marchac V, Scheinmann P. Complications of flexible bronchoscopy in children: prospective study of 1328 procedures. Eur Respir J 2002 20 : 1271 6.
18. Joshi P, Kakakios A, Jayasekera J, Isaacs D. A comparison of IL-2 levels in nasopharyngeal and endotracheal aspirates of babies with respiratory syncytial viral bronchiolitis. J Allergy Clin Immunol 1998 102 : 618 20.
19. Colombo JL, Hallberg TK. Pulmonary aspiration and lipid-laden macrophages: In search of Gold standards. Pediatr Pulmonol 1999 28 : 79 82.
20. Adams R, Ruffin R, Campbell D. The value of the lipid-laden macrophage index in the assessment of aspiration pneumonia. Aust N Z J Med 1997 27 : 550 3.
21. Elidemir O, Fan LL, Colasurdo N. A novel diagnostic method for pulmonary aspiration in a murine model: immunocytochemical staining of milk proteins in alveolar macrophages. Am J Respir Crit Care Med 2000 161 : 622 6.
22. Kazachkov MY, Muhlebach MS, Livasy CA, Noah TL. Lipid- laden macrophage index and inflammation in bronchoaveolar lavage fluids in children. Eur Respir J 2001 18 : 790 5.
23. Malfroot A, Vandenplas Y, Verlinden M, Piepsz A, Dab I. Gastroesophageal reflux and unexplained chronic respiratory disease in infants and children. Pediatr Pulmonol 1987 3 : 208 13.
24. Ahrens P, Noll C, Kitz R, Willigens P, Zielen S, Hofmann D. Lipid-laden alveolar macrophages (LLAM): a useful marker of silent aspiration in children. Pediatr Pulmonol 1999 28 : 83 8.
25. O'Hare B, Lerman J, Endo J, Cutz E. Acute lung injury after instillation of human breast milk or infant formula into rabbits' lungs. Anesthesiology 1996 84 : 1386 91.
26. Sacco O, Fregonese B, Silvestri M, Sabatini F, Mattioli G, Rossi GA. Bronchoalveolar lavage and esophageal pH monitoring data in children with "difficult to treat" respiratory symptoms. Pediatr Pulmonol 2000 30 : 313 9.
27. Everard ML, Swarbrick A, Wrightham M, McIntyre J, Dunkley C, James PD, et al. Analysis of cells obtained by bronchial lavage of infants with respiratory syncytial virus infection. Arch Dis Child 1994 71 : 428 32.
28. Smith P, Wang SZ, Dowling K, Forsyth K. Leukocyte populations in respiratory syncytial virus-induced bronchiolitis. J Paediatr Child Health 2001 37 : 146 51.