Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 14, 2007, Pages 4026-4029

  Blecha, Joseph E ^a   Anderson, Marc O ^a   Chow, Jennifer M ^a   Guevarra, Christle C ^a   Pender, Celia ^b   Penaranda, Cristina ^b   Zavodovskaya, Marianna ^b   Youngren, Jack F ^b   Berkman, Clifford E ^a  

^a SAN FRANCISCO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

15 Lipoxygenase; 15 LOX; IGF 1R; Insulin like growth factor 1 receptor; NDGA; Nordihydroguaiaretic acid

Indexed keywords

ARACHIDONATE 15 LIPOXYGENASE; CATECHOL; FUNCTIONAL GROUP; LARREA DIVARICATA EXTRACT; LIPOXYGENASE; LIPOXYGENASE INHIBITOR; NORDIHYDROGUAIARETIC ACID; PLANT EXTRACT; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL GROWTH; CELL STRAIN MCF 7; DRUG ACTIVITY; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LARREA; LARREA DIVARICATA; STRUCTURE ACTIVITY RELATION; TECHNIQUE;

BREAST NEOPLASMS; CELL LINE, TUMOR; HUMANS; LIPOXYGENASE INHIBITORS; NORDIHYDROGUAIARETIC ACID; RECEPTOR, IGF TYPE 1;

LARREA DIVARICATA;

EID: 34250377801     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.04.092     Document Type: Article

References (31)

1. Waller C.W., and Gisvold O. J. Am. Pharm. Assoc. Sci. 34 (1945) 78
2. Avis I.M., Jett M., Boyle T., Vos M.D., Moody T., Treston A.M., Martinez A., and Mulshine J.L. J. Clin. Invest. 97 (1996) 806
3. Youngren J.F., Gable K., Penaranda C., Maddux B.A., Zavodovskaya M., Lobo M., Campbell M., Kerner J., and Goldfine I.D. Breast Cancer Res.Treat. 94 (2005) 37
4. Domin J., Higgins T., and Rozengurt E. J. Biol. Chem. 269 (1994) 8260
5. Korc M., Chandrasekar B., Yamanaka Y., Friess H., Buchler M., and Beger H.G. J. Clin. Invest. 90 (1992) 1352
6. Bergmann U., Funatomi H., Yokoyama M., Beger H.G., and Korc M. Cancer Res. 55 (1995) 2007
7. Yamanaka Y., Friess H., Kobrin M.S., Buchler M., Kunz J., Beger H.G., and Korc M. Hum. Pathol. 24 (1993) 1127
8. Li B.H., Ma X.F., Wang Y., and Tian W.X. J. Biochem. (Tokyo) 138 (2005) 679
9. Maria M.A., Morrissey C., O'Keane C., Mulligan N., Watson C., Smith J., Fitzpatrick J.M., and Watson R.W. Cancer 106 (2006) 2743
10. De Schrijver E., Brusselmans K., Heyns W., Verhoeven G., and Swinnen J.V. Cancer Res. 63 (2003) 3799
11. Van Wauwe J., and Goossens J. Prostaglandins 26 (1983) 725
12. Chang J., Skowronek M.D., Cherney M.L., and Lewis A.J. Inflammation 8 (1984) 143
13. Cooke R.G., and Ahmad N. J. Endocrinol. 142 (1994) 47
14. Miyazawa K., Iimori Y., Makino M., Mikami T., and Miyasaka K. Jpn. J. Pharmacol. 38 (1985) 199
15. Jiang W.G., Watkins G., Douglas-Jones A., and Mansel R.E. Prostaglandins Leukot. Essent. Fatty Acids 74 (2006) 235
16. Kucab J.E., and Dunn S.E. Breast Dis. 17 (2003) 41
17. Topliss J.G. J. Med. Chem. 20 (1977) 463
18. Topliss J.G. J. Med. Chem. 15 (1972) 1006
19. McDonald R.W., Bunjobpon W., Liu T., Fessler S., Pardo O.E., Freer I.K., Glaser M., Seckl M.J., and Robins D.J. Anticancer Drug Des. 16 (2001) 261
20. O'Neill J.A., Gallagher O.P., Devine K.J., Jones P.W., and Maguire A.R. J. Nat. Prod. 68 (2005) 125
21. Monte W.T., and Lindbeck A.C. Org. Proc. Res. Devel. 5 (2001) 267
22. Pavlenko N.V. Uspekhi. Khimii. 58 (1989) 767
23. Brana M.F., Cacho M., Garcia M.L., Mayoral E.P., Lopez B., de Pascual-Teresa B., Ramos A., Acero N., Llinares F., Munoz-Mingarro D., Lozach O., and Meijer L. J. Med. Chem. 48 (2005) 6843
24. Cram D.J., Sahyun M.R.V., and Knox G.R. J. Am. Chem. Soc. 84 (1962) 1734
25. Vickery E.H., Pahler L.F., and Eisenbraun E.J. J. Org. Chem. 44 (1979) 4444
26. Koelsch C.F. J. Am. Chem. Soc. 68 (1946) 148
27. Howell, S.; Khandwala, A.; Sachdey, O. P.; Smith, C. G. U.S. Patent 5,541,232, 1996.
28. McDonald R.W., Bunjobpon W., Liu T., Fessler S., Pardo O.E., Freer I.K.A., Glaser M., Seckl M.J., and Robins D.J. Anticancer Drug Des. 16 (2001) 261
29. West C.T., Donnelly S.J., Kooistra D.A., and Doyle M.P. J. Org. Chem. 38 (1973) 2675
30. Gnabre J., Huang R.C.C., Bates R.B., Burns J.J., Caldera S., Malcomson M.E., and Mcclure K.J. Tetrahedron 51 (1995) 12203
31. Whitman S., Gezginci M., Timmermann B.N., and Holman T.R. J. Med. Chem. 45 (2002) 2659