Severe paraneoplastic hyponatremia and hypoosmolality in a patient with small-cell lung carcinoma: Syndrome of inappropriate antidiuretic hormone secretion versus atrial natriuretic peptide or both?

Clinical Lung Cancer

Volumn 8, Issue 6, 2007, Pages 392-395

  Radulescu, Dan ^a   Bunea, Delia ^a   Pripon, Sorin ^a   Duncea, Caius ^a   Radulescu, Letitia ^b  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b Oncologic Institute   (Romania)

Author keywords

Histopathology; Immunohistochemistry; Radiography

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE; AMLODIPINE; AMOXICILLIN; ANTIBIOTIC AGENT; ATRIAL NATRIURETIC FACTOR; BRONCHODILATING AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; DEMECLOCYCLINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOXORUBICIN; ENOLASE; EOSIN; ETOPOSIDE; HEMATOXYLIN; PERINDOPRIL; SODIUM CHLORIDE; THEOPHYLLINE; TOPOTECAN; TUMOR MARKER; VASOPRESSIN; VINCRISTINE;

ADULT; ALCOHOL CONSUMPTION; ANAMNESIS; ARTICLE; CANCER STAGING; CARDIOVASCULAR DISEASE; CASE REPORT; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CLINICAL FEATURE; COMA; CONFUSION; DISEASE DURATION; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG EFFICACY; HEART VENTRICLE HYPERTROPHY; HEPATOMEGALY; HUMAN; HUMAN TISSUE; HYPERTENSION; HYPONATREMIA; LABORATORY TEST; LIVER METASTASIS; LUNG BIOPSY; LUNG SMALL CELL CANCER; MALE; MULTIPLE CYCLE TREATMENT; MUSCLE SPASM; PARANEOPLASTIC SYNDROME; PHYSICAL EXAMINATION; PLASMA OSMOLALITY; PROTEIN DETERMINATION; SALT LOSING NEPHRITIS; SPINAL CORD METASTASIS; TREATMENT OUTCOME; VASOPRESSIN RELEASE; WATER DEPRIVATION;

EID: 34250373331     PISSN: 15257304     EISSN: None     Source Type: Journal    
DOI: 10.3816/CLC.2007.n.022     Document Type: Article

References (14)

1. Johnson BE, Chute JP, Rushin J, et al. A prospective study of patients with lung cancer and hyponatremia of malignancy. Am J Respir Crit Care Med 1997; 156:1669-1678.
2. Bracco D, Favre JB, Ravussin P. Hyponatremia in neurologic intensive care: cerebral salt wasting syndrome and inappropriate antidiuretic hormone secretion. Ann Fr Anesth Reanim 2001; 20:203-212.
3. Marchioli CC, Graziano SL. Paraneoplastic syndromes associated with small cell lung cancer. Chest Surg Clin N Am 1997; 7:65-80.
4. Bliss DP, Battey JF, Linnoila RI, et al. Expression of the atrial natriuretic factor gene in small cell lung cancer tumors and tumor cell lines. J Natl Cancer Inst 1990; 82:305-310.
5. Campling BG, Sarda IR, Baer KA, et al. Secretion of atrial natriuretic peptide and vasopressin by small cell lung cancer. Cancer 1995; 75:2442-2451.
6. Gross AJ, Steinberg SM, Reilly JG, et al. Atrial natriuretic factor and arginine vasopressin production in tumor cell lines from patients with lung cancer and their relationship to serum sodium. Cancer Res 1993; 53:67-74.
7. Cogan E, Debieve MR Philipart I, et al. High plasma levels of atrial natriuretic factor in SIADH. N Eng J Med 1986; 314:1258-1259.
8. Donckier JE, Meunier HT, Ketelslegers JM, et al. Atrial natriuretic peptide and the syndrome of inappropriate secretion of antidiuretic hormone. Ann Intern Med 1986; 105:795-796.
9. Chute JP, Taylor E, Williams J, et al. A metabolic study of patiens with lung cancer and hyponatremia of malignancy. Clin Cancer Res 2006; 12:888-896.
10. Wu F, Wu Q. Corin-mediated processing of pro-atrial natriuretic peptide in human small cell lung cancer cells. Cancer Res 2003; 63:8318-8322.
11. Wu F, Yan W, Pan J, et al. Processing of pro-atrial natriuretic pepride by corin in cardiac myocytes. J Biol Chem 2002; 277:16900-16905.
12. Yan W, Wu F, Morser J, et al. Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme. Proc Natl Acad Sci U S A 2000; 97:8525-8529.
13. Kinzie BJ. Management of the syndrome of inappropriate secretion of antidiuretic hormone. Clin Pharm 1987; 6:625-633.
14. Goh KP. Management of hyponatremia. Am Fam Physician 2004; 69:2387-2394.