메뉴 건너뛰기




Volumn 97, Issue 6, 2007, Pages 1187-1195

Amla (Emblica officinalis Gaertn.)prevents dyslipidaemia and oxidative stress in the ageing process

Author keywords

Ageing; Amla; Dyslipidaemia; Oxidative stress

Indexed keywords

CHOLESTEROL; CYCLOOXYGENASE 2; EMBLICA OFFICINALIS EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPID; LIVER PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN BAX; PROTEIN BCL 2; SUNAMLA; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 34250372474     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114507691971     Document Type: Article
Times cited : (102)

References (60)
  • 1
    • 0036136676 scopus 로고    scopus 로고
    • Flavonoids from Emblica officinalis and Mangifera indica - effectiveness for dyslipidemia
    • Anila L & Vijayalakshmi NR (2002) Flavonoids from Emblica officinalis and Mangifera indica - effectiveness for dyslipidemia. J Ethnopharmacol 79, 81-87.
    • (2002) J Ethnopharmacol , vol.79 , pp. 81-87
    • Anila, L.1    Vijayalakshmi, N.R.2
  • 2
    • 0141609046 scopus 로고    scopus 로고
    • Antioxidant action of flavonoids from Mangifera indica and Emblica officinalis in hypercholesterolemic rats
    • Anila L & Vijayalakshmi NR (2003) Antioxidant action of flavonoids from Mangifera indica and Emblica officinalis in hypercholesterolemic rats. Food Chemistry 83, 569-574.
    • (2003) Food Chemistry , vol.83 , pp. 569-574
    • Anila, L.1    Vijayalakshmi, N.R.2
  • 3
  • 4
    • 0035174615 scopus 로고    scopus 로고
    • The transcription factor NF-κB and human disease
    • Baldwin AS (2001) The transcription factor NF-κB and human disease. J Clin Invest 107, 3-6.
    • (2001) J Clin Invest , vol.107 , pp. 3-6
    • Baldwin, A.S.1
  • 5
    • 0034126144 scopus 로고    scopus 로고
    • The role of antioxidant activity of Phyllanthus emblica fruits on prevention from indomethacin induced gastric ulcer
    • Bandyopadhyay SK, Pakrashi SC & Pakrashi A (2000) The role of antioxidant activity of Phyllanthus emblica fruits on prevention from indomethacin induced gastric ulcer. J Ethnopharmacol 70 171-176.
    • (2000) J Ethnopharmacol , vol.70 , pp. 171-176
    • Bandyopadhyay, S.K.1    Pakrashi, S.C.2    Pakrashi, A.3
  • 7
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Berkman KB & Ames BN (1998) The free radical theory of aging matures. Physiol Rev 78, 547-581.
    • (1998) Physiol Rev , vol.78 , pp. 547-581
    • Berkman, K.B.1    Ames, B.N.2
  • 9
  • 10
    • 0041887308 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Regulation of transcriptional activities and roles in inflammation
    • Blanquart C, Barbier O, Fruchart JC, Staels B & Glineur C (2003) Peroxisome proliferator-activated receptors: Regulation of transcriptional activities and roles in inflammation. J Steroid Biochem Mol Biol 85, 267-273.
    • (2003) J Steroid Biochem Mol Biol , vol.85 , pp. 267-273
    • Blanquart, C.1    Barbier, O.2    Fruchart, J.C.3    Staels, B.4    Glineur, C.5
  • 11
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buege JA & Aust SD (1978) Microsomal lipid peroxidation. Methods Enzymol 52, 302-306.
    • (1978) Methods Enzymol , vol.52 , pp. 302-306
    • Buege, J.A.1    Aust, S.D.2
  • 12
    • 1542616703 scopus 로고    scopus 로고
    • Proteins of the bcl-2 family in apoptosis signalling: From mechanistic insights to therapeutic opportunities
    • Chan SL & Yu VC (2004) Proteins of the bcl-2 family in apoptosis signalling: From mechanistic insights to therapeutic opportunities. Clin Exp Pharmacol Physiol 31, 119-128.
    • (2004) Clin Exp Pharmacol Physiol , vol.31 , pp. 119-128
    • Chan, S.L.1    Yu, V.C.2
  • 14
    • 20344407841 scopus 로고    scopus 로고
    • Resveratrol as an and-inflammatory and anti-aging agent: Mechanisms and clinical implications
    • De la Lastra, CA & Villegas I (2005) Resveratrol as an and-inflammatory and anti-aging agent: Mechanisms and clinical implications. Mol Nutr Food Res 49, 405-430.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 405-430
    • De la Lastra, C.A.1    Villegas, I.2
  • 16
    • 0028915214 scopus 로고
    • Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase
    • El-Mekkawy S, Meselhy MR, Kusumoto, IT, Kadota, S, Hattori M & Namba, T (1995) Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase. Chem Pharm Bull 43, 641-648.
    • (1995) Chem Pharm Bull , vol.43 , pp. 641-648
    • El-Mekkawy, S.1    Meselhy, M.R.2    Kusumoto, I.T.3    Kadota, S.4    Hattori, M.5    Namba, T.6
  • 18
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch J, Lees M & Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226, 497-509.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 19
    • 2742589144 scopus 로고    scopus 로고
    • Active constituents of Emblica officinalis: Part 1 - The chemistry and antioxidant effects of two new hydrolysable tannins, emblicanin A and B
    • Ghosal S, Tripathi VK & Chauhan S (1996) Active constituents of Emblica officinalis: Part 1 - The chemistry and antioxidant effects of two new hydrolysable tannins, emblicanin A and B. Indian J Chem 35B, 941-948.
    • (1996) Indian J Chem , vol.35 B , pp. 941-948
    • Ghosal, S.1    Tripathi, V.K.2    Chauhan, S.3
  • 20
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR & Reed JC (1998) Mitochondria and apoptosis. Science 281, 1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 21
    • 0027300736 scopus 로고
    • Lipid peroxidation: Its mechanism measurement and significance
    • Halliwell B & Chirico S (1993) Lipid peroxidation: Its mechanism measurement and significance. Am J Clin Nutr 57, 715-725.
    • (1993) Am J Clin Nutr , vol.57 , pp. 715-725
    • Halliwell, B.1    Chirico, S.2
  • 23
    • 0031589571 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor α (PPARα) regulates the plasma thiobarbituric acid-reactive substance (TBARS) level
    • Inoue I, Noji S, Shen MZ, Takahashi K & Katayama S (1997) The peroxisome proliferator-activated receptor α (PPARα) regulates the plasma thiobarbituric acid-reactive substance (TBARS) level. Biochem Biophys Res Commun 237, 606-610.
    • (1997) Biochem Biophys Res Commun , vol.237 , pp. 606-610
    • Inoue, I.1    Noji, S.2    Shen, M.Z.3    Takahashi, K.4    Katayama, S.5
  • 24
    • 17344390044 scopus 로고    scopus 로고
    • Fibrate and statin synergistically increase the transcriptional activities of PPARα/RXRα and decrease the transactivation of NFκB
    • Inoue I, Itoh F, Aoyagi S, et al. (2002) Fibrate and statin synergistically increase the transcriptional activities of PPARα/RXRα and decrease the transactivation of NFκB. Biochem Biophys Res Commun 290, 131-139.
    • (2002) Biochem Biophys Res Commun , vol.290 , pp. 131-139
    • Inoue, I.1    Itoh, F.2    Aoyagi, S.3
  • 25
    • 50549198780 scopus 로고
    • A micro-biuret method for estimating proteins
    • Itzhaki RF & Gill DM (1964) A micro-biuret method for estimating proteins. Anal Biochem 9, 401-410.
    • (1964) Anal Biochem , vol.9 , pp. 401-410
    • Itzhaki, R.F.1    Gill, D.M.2
  • 26
    • 77957010110 scopus 로고
    • Isolation of liver or kidney mitochondria
    • Johnson D & Lardy H (1967) Isolation of liver or kidney mitochondria. Methods Enzymol X, 94-96.
    • (1967) Methods Enzymol , vol.10 , pp. 94-96
    • Johnson, D.1    Lardy, H.2
  • 27
    • 84996001121 scopus 로고
    • Antioxidant activity of E. officinalis
    • Jose JK & Kuttan R (1995) Antioxidant activity of E. officinalis. J Clin Biochem Nutr 19, 63-70.
    • (1995) J Clin Biochem Nutr , vol.19 , pp. 63-70
    • Jose, J.K.1    Kuttan, R.2
  • 28
    • 0035047879 scopus 로고    scopus 로고
    • Antitumour activity of Emblica officinalls
    • Jose JK, Kuttan G & Kuttan R (2001) Antitumour activity of Emblica officinalls. J Ethnopharmacol 75, 65-69.
    • (2001) J Ethnopharmacol , vol.75 , pp. 65-69
    • Jose, J.K.1    Kuttan, G.2    Kuttan, R.3
  • 29
    • 0021992163 scopus 로고
    • Influence of cyclosporin A on the respiration of isolated rat kidney mitochondria
    • Jung K & Pergande M (1985) Influence of cyclosporin A on the respiration of isolated rat kidney mitochondria. FEBS Lett 193, 167-169.
    • (1985) FEBS Lett , vol.193 , pp. 167-169
    • Jung, K.1    Pergande, M.2
  • 31
    • 31444441067 scopus 로고    scopus 로고
    • Influence of amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats
    • Kim HJ, Yokozawa T, Kim HY, Tohda C, Rao TP & Juneja LR (2005) Influence of amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats. J Nutr Sci Vitaminol 51, 413-418.
    • (2005) J Nutr Sci Vitaminol , vol.51 , pp. 413-418
    • Kim, H.J.1    Yokozawa, T.2    Kim, H.Y.3    Tohda, C.4    Rao, T.P.5    Juneja, L.R.6
  • 32
    • 0037093677 scopus 로고    scopus 로고
    • Molecular exploration of age-related NF-κB/IKK downregulation by calorie restriction in rat kidney
    • Kim HJ, Yu BP & Chung HY (2002) Molecular exploration of age-related NF-κB/IKK downregulation by calorie restriction in rat kidney. Free Radic Biol Med 32, 991-1005.
    • (2002) Free Radic Biol Med , vol.32 , pp. 991-1005
    • Kim, H.J.1    Yu, B.P.2    Chung, H.Y.3
  • 33
    • 0034565044 scopus 로고    scopus 로고
    • The biochemistry of aging
    • Knight JA (2001) The biochemistry of aging. Adv Clin Chem 35 1-62.
    • (2001) Adv Clin Chem , vol.35 , pp. 1-62
    • Knight, J.A.1
  • 34
    • 0018362272 scopus 로고
    • Age-related changes in rat and primate plasma cholesterol metabolism
    • Lacko AG & Davis JL (1979) Age-related changes in rat and primate plasma cholesterol metabolism. J Am Geriatr Soc 5, 212-217.
    • (1979) J Am Geriatr Soc , vol.5 , pp. 212-217
    • Lacko, A.G.1    Davis, J.L.2
  • 35
    • 0034253463 scopus 로고    scopus 로고
    • Role of redox-regulated transcription factors in inflammation, aging and age-related diseases
    • Lavrovsky Y, Chatterjee B, Clark RA & Roy AK (2000) Role of redox-regulated transcription factors in inflammation, aging and age-related diseases. Exp Gerontol 35, 521-532.
    • (2000) Exp Gerontol , vol.35 , pp. 521-532
    • Lavrovsky, Y.1    Chatterjee, B.2    Clark, R.A.3    Roy, A.K.4
  • 36
    • 0036781052 scopus 로고    scopus 로고
    • NF-κB regulation in the immune system
    • Li Q & Verma IM (2002) NF-κB regulation in the immune system. Nat Immunol 2, 725-734.
    • (2002) Nat Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 37
    • 2642545220 scopus 로고    scopus 로고
    • The oxidative damage theory of aging
    • Lin MT & Beal MF (2003) The oxidative damage theory of aging. Clin Neurosci Res 2, 305-315.
    • (2003) Clin Neurosci Res , vol.2 , pp. 305-315
    • Lin, M.T.1    Beal, M.F.2
  • 38
    • 0017965844 scopus 로고
    • Atherosclerotic disorder and lipid peroxidation
    • Naito C & Yamanaka T (1978) Atherosclerotic disorder and lipid peroxidation. Jpn J Geriatr 15, 187-191.
    • (1978) Jpn J Geriatr , vol.15 , pp. 187-191
    • Naito, C.1    Yamanaka, T.2
  • 39
    • 0037195866 scopus 로고    scopus 로고
    • Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric oxide synthase in human astrocytes
    • Pahan K, Jana M, Liu X, Taylor BS, Wood C & Fischer SM (2002) Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric oxide synthase in human astrocytes. J Biol Chem 277, 45984-45991.
    • (2002) J Biol Chem , vol.277 , pp. 45984-45991
    • Pahan, K.1    Jana, M.2    Liu, X.3    Taylor, B.S.4    Wood, C.5    Fischer, S.M.6
  • 40
    • 0032893056 scopus 로고    scopus 로고
    • Cholesterol and lipoprotein metabolism in aging: Reversal of hypercholesterolemia by growth hormone treatment in old rats
    • Parini P, Angelin B & Rudling M (1999) Cholesterol and lipoprotein metabolism in aging: Reversal of hypercholesterolemia by growth hormone treatment in old rats. Arterioscler Thromb Vasc Biol 19, 832-839.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 832-839
    • Parini, P.1    Angelin, B.2    Rudling, M.3
  • 42
    • 0030766476 scopus 로고    scopus 로고
    • Alteration in lipoprotein metabolism in peroxisome proliferator-activated receptor-α deficient mice
    • Peters JM, Hennuyer N, Staels B, Fruchart JC, Fievet C, Gonzalez FJ & Auwerx J (1997) Alteration in lipoprotein metabolism in peroxisome proliferator-activated receptor-α deficient mice. J Biol Chem 272, 28307-28312.
    • (1997) J Biol Chem , vol.272 , pp. 28307-28312
    • Peters, J.M.1    Hennuyer, N.2    Staels, B.3    Fruchart, J.C.4    Fievet, C.5    Gonzalez, F.J.6    Auwerx, J.7
  • 44
    • 0032484123 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor α activation modulates cellular redox status, represses nuclear factor-κB signaling, and reduces inflammatory cytokine production in aging
    • Poynter ME & Daynes RA (1998) Peroxisome proliferator-activated receptor α activation modulates cellular redox status, represses nuclear factor-κB signaling, and reduces inflammatory cytokine production in aging. J Biol Chem 273, 32833-32941.
    • (1998) J Biol Chem , vol.273 , pp. 32833-32941
    • Poynter, M.E.1    Daynes, R.A.2
  • 45
    • 0035450498 scopus 로고    scopus 로고
    • New roles fbf PPARs in cholesterol homeostasis
    • Ricote M & Glass CK (2001) New roles fbf PPARs in cholesterol homeostasis. Trends Pharmacol Sci 22, 441-443.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 441-443
    • Ricote, M.1    Glass, C.K.2
  • 46
    • 0036284599 scopus 로고    scopus 로고
    • Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property
    • Sabu MC & Kuttan R (2002) Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol 81, 155-160.
    • (2002) J Ethnopharmacol , vol.81 , pp. 155-160
    • Sabu, M.C.1    Kuttan, R.2
  • 48
    • 2942596005 scopus 로고    scopus 로고
    • Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasm membrane in the commitment to apoptosis
    • Samhan-Arias AK, Martín-Romero FJ & Gutiérrez-Merino C (2004) Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasm membrane in the commitment to apoptosis. Free Radic Biol Med 37 48-61.
    • (2004) Free Radic Biol Med , vol.37 , pp. 48-61
    • Samhan-Arias, A.K.1    Martín-Romero, F.J.2    Gutiérrez-Merino, C.3
  • 50
    • 4444262821 scopus 로고    scopus 로고
    • Prevention of age-related changes in rat cortex transcription factor activator protein-1 by hypolipidemic drugs
    • Sanguino E, Roglans N, Alegret M, Sánchez RM, Vázquez-Carrera M & Laguna JC (2004b) Prevention of age-related changes in rat cortex transcription factor activator protein-1 by hypolipidemic drugs. Biochem Pharmacol 68, 1411-1421.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1411-1421
    • Sanguino, E.1    Roglans, N.2    Alegret, M.3    Sánchez, R.M.4    Vázquez-Carrera, M.5    Laguna, J.C.6
  • 52
    • 0030828307 scopus 로고    scopus 로고
    • Constitutive activation of NF-κB in an animal model of aging
    • Spencer NF, Poynter ME, Im SY & Daynes,RA (1997) Constitutive activation of NF-κB in an animal model of aging. Int Immunol 9, 1581-1588.
    • (1997) Int Immunol , vol.9 , pp. 1581-1588
    • Spencer, N.F.1    Poynter, M.E.2    Im, S.Y.3    Daynes, R.A.4
  • 53
    • 0021956113 scopus 로고
    • Emblica officinalis reduces serum, aortic and hepatic cholesterol in rabbits
    • Thakur CP (1985) Emblica officinalis reduces serum, aortic and hepatic cholesterol in rabbits. Experientia 41, 423-424.
    • (1985) Experientia , vol.41 , pp. 423-424
    • Thakur, C.P.1
  • 54
    • 0033924298 scopus 로고    scopus 로고
    • Lipid metabolism in the elderly
    • Toth MJ & Tehernof A (2000) Lipid metabolism in the elderly. Eur J Clin Nutr 54, S121-S125.
    • (2000) Eur J Clin Nutr , vol.54
    • Toth, M.J.1    Tehernof, A.2
  • 55
    • 0035162008 scopus 로고    scopus 로고
    • Ageing and the free radical theory
    • Wickens AP (2001) Ageing and the free radical theory, Respir Physiol 128, 379-391.
    • (2001) Respir Physiol , vol.128 , pp. 379-391
    • Wickens, A.P.1
  • 57
    • 0036860951 scopus 로고    scopus 로고
    • Dose effect of oxidative stress on signal transduction in aging
    • Yoon SO, Yun CH & Chung AS (2002) Dose effect of oxidative stress on signal transduction in aging. Mech Ageing Dev 123, 1597-1604.
    • (2002) Mech Ageing Dev , vol.123 , pp. 1597-1604
    • Yoon, S.O.1    Yun, C.H.2    Chung, A.S.3
  • 59
    • 33645870996 scopus 로고    scopus 로고
    • Adaptive mechanisms to oxidative stress during aging
    • Yu BP & Chung HY (2006) Adaptive mechanisms to oxidative stress during aging. Mech Ageing Dev 127, 436-443.
    • (2006) Mech Ageing Dev , vol.127 , pp. 436-443
    • Yu, B.P.1    Chung, H.Y.2
  • 60
    • 0034980861 scopus 로고    scopus 로고
    • New phenolic constituents from the fruit juice Phyllanthus emblica
    • Zhang YJ, Tanaka T, Yang CR & Kouno I (2001) New phenolic constituents from the fruit juice Phyllanthus emblica. Chem Pharm Bull 49 537-540.
    • (2001) Chem Pharm Bull , vol.49 , pp. 537-540
    • Zhang, Y.J.1    Tanaka, T.2    Yang, C.R.3    Kouno, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.