Cerebral sinus occlusion in a boy presenting with asparaginase-induced hypertriglyceridemia

Klinische Padiatrie

Volumn 219, Issue 2, 2007, Pages 95-96

  Dietel, V ^a   Buhrdel P ^a   Hirsch, W ^a   Korholz D ^a   Kiess, W ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Asparaginase; Cerebral sinus venous thrombosis; Hypertriglyceridemia; Leukaemia

Indexed keywords

ASPARAGINASE MACROGOL; BENZOIC ACID; BEZAFIBRATE; DEXAMETHASONE; LOW MOLECULAR WEIGHT HEPARIN; ANTICOAGULANT AGENT; ANTILIPEMIC AGENT; ANTINEOPLASTIC AGENT; ASPARAGINASE; MACROGOL DERIVATIVE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ANTICOAGULANT THERAPY; ARTICLE; CANCER CHEMOTHERAPY; CASE REPORT; CEREBRAL SINUS THROMBOSIS; CLINICAL FEATURE; GLAUCOMA; HUMAN; HYPERAMMONEMIA; HYPERTRIGLYCERIDEMIA; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; TREATMENT OUTCOME; CHEMICALLY INDUCED DISORDER; DRUG COMBINATION; FEMALE; T CELL LEUKEMIA;

ADOLESCENT; ANTICOAGULANTS; ANTILIPEMIC AGENTS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ASPARAGINASE; BEZAFIBRATE; DRUG THERAPY, COMBINATION; FEMALE; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS; HYPERTRIGLYCERIDEMIA; LEUKEMIA, T-CELL, ACUTE; MAGNETIC RESONANCE ANGIOGRAPHY; POLYETHYLENE GLYCOLS; SINUS THROMBOSIS, INTRACRANIAL;

EID: 34250367554     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-921455     Document Type: Article

References (8)

1. Athale UH, Chan AKC: Thrombosis in children with acute lymphoblastic leukemia Part II Pathogenesis of thrombosis in children with acute lymphoblastic leukemia: effects of the disease and therapy. Thrombosis Research 2003; 111: 199-212
2. Cremer P, Lakomek M, Beck W et al: The effect of L-asparaginase on lipid metabolism during induction chemotherapy of childhood lymphoblastic leukemia. Eur J Pediatr 1988; 147: 64-67
3. Hoogerbrugge N, Jansen H, Hoogerbrugge PM: Transient hyperlipidemia during treatment of ALL with L-asparaginase is related to decreased lipoprotein lipase activity. Leukemia 1997; 11: 1377-1379
4. Keung YK, Rizk R, Wu XY, Cobos E: Drug-induced hypertriglyceridemia with and without pancreatitis. South Med J 1999; 92: 912-914
5. Mauz-Körholz C, Nürnberger W, Irsfeld H, Körholz D, Göbel U: Low rate of severe venous thrombosis in children with ALL treatment according to COALL-92 and -97 protocol. Klin Pädiatr 1999; 211: 215-217
6. Mauz-Körholz C, Junker R, Göbel U, Nowak-Göttl U: Prothrombotic risk faktors in children with acute lymphoblastic leukemia treated with delayed E. coli asparaginase (COALL-92 and -97 protocols). Thromb Haemost 2000; 83: 840-843
7. Mitchell L et al: Trend to efficacy and safety using antithrombin concentrate in prevention of thrombosis in children receiving l-asparaginase for acute lymphoblastic leukemia. Results of the PAARKA study. Thromb Haemost 2003; 90: 163-164
8. Muller HJ, Boos J: Use of L-Asparaginase in childhood ALL. Crit Rev Oncol/Hematol 1998; 28: 97-113