Genetic association studies and false discoveries [6]

JAMA

Volumn 297, Issue 22, 2007, Pages 2477-2478

  Horne, Benjamin D ^a  

^a LDS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; CLINICAL PRACTICE; DIAGNOSTIC VALUE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; HAPLOTYPE; HUMAN; LABORATORY DIAGNOSIS; LETTER; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VEIN THROMBOSIS; BIOLOGICAL MODEL; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; NOTE; REPRODUCIBILITY; RISK;

GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRODUCIBILITY OF RESULTS; RISK; VENOUS THROMBOSIS;

EID: 34250331693     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.297.22.2477-b     Document Type: Letter

References (6)

1. Ioannidis JP, Ntzani EE, Trikalinos TA, Contopoulos-Ioannidis DG. Replication validity of genetic association studies. Nat Genet. 2001;29:306-309.
2. Hegele RA. SNP judgments and freedom of association. Arterioscler Thromb Vasc Biol. 2002;22:1058-1061.
3. Smith NL, Hindorff LA, Heckbert SR, et al. Association of genetic variations with nonfatal venous thrombosis in postmenopausal women. JAMA. 2007;297:489-498.
4. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B. 1995;57:289-300.
5. Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci U S A. 2003;100:9440-9445.
6. Havill LM, Dyer TD. Association mapping: methodologies, strategies, and issues. Genet Epidemiol. 2005;29(suppl 1):S77-S85.