S100B serum level predicts computed tomography findings after minor head injury

Journal of Trauma - Injury, Infection and Critical Care

Volumn 62, Issue 6, 2007, Pages 1452-1456

  Müller, Kay ^a   Townend, Will ^c   Biasca, Nicola ^d   Undén, Johan ^e   Waterloo, Knut ^a,b   Romner, Bertil ^a,b,e   Ingebrigtsen, Tor ^a,b  

^a UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^b UNIVERSITY OF TROMSØ   (Norway)

^c Hope University Hospital   (United Kingdom)

^d Spital Oberengadin ^*  (Switzerland)

^e LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Computed tomography; Guidelines; Head injury; Protein S100B

Indexed keywords

PROTEIN S100B;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; BRAIN INJURY; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC ACCURACY; FEMALE; HEAD INJURY; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; ROC CURVE; STATISTICAL SIGNIFICANCE;

BIOLOGICAL MARKERS; CRANIOCEREBRAL TRAUMA; GLASGOW COMA SCALE; HUMANS; NERVE GROWTH FACTORS; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; S100 PROTEINS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 34250327073     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e318047bfaa     Document Type: Article

References (27)

1. Servadei F, Teasdale G, Merry G. Defining acute mild head injury in adults: a proposal based on prognostic factors, diagnosis, and management. J Neurotrauma. 2001;18:657-664.
2. National Institute for Clinical Excellence. Head injury. Triage, assessment, investigation and early management of head injury in infants, children and adults. Available at: http://www.nice.org.uk/pdf/cg4niceguideline. pdf. Accessed August 28, 2005.
3. Ingebrigtsen T, Romner B, Kock-Jensen C. Scandinavian guidelines for initial management of minimal, mild, and moderate head injuries. J Trauma. 2000;48:760-766.
4. Stiell IG, Wells GA, Vandemheen K, et al. The Canadian CT Head Rule for patients with minor head injury. Lancet. 2001;357:1391-1396.
5. Vos PE, Battistin L, Birbamer G, et al. EFNS guideline on mild traumatic brain injury: report of an EFNS task force. Eur J Neurol. 2002;9:207-219.
6. Ingebrigtsen T, Romner B, Marup-Jensen S, et al. The clinical value of serum S-100 protein measurements in minor head injury: a Scandinavian multicentre study. Brain Inj. 2000;14:1047-1055.
7. Biberthaler P, Linsenmeier U, Pfeifer K-J, et al. Serum S-100B concentration provides additional information for the indication of computed tomography in patients after minor head injury. A prospective multicenter study. Shock. 2006;25:446-453.
8. Ingebrigtsen T, Romner B. Biochemical serum markers of traumatic brain injury. J Trauma. 2002;52:798-808.
9. Savola O, Hillbom M. Early predictors of post-concussion symptoms in patients with mild head injury. Eur J Neurol. 2003;10:175-181.
10. Ingebrigtsen T, Romner B. Biochemical serum markers for brain damage: a short review with emphasis on clinical utility in mild head injury. Restor Neurol Neurosci. 2003;21:171-176.
11. Romner B, Ingebrigtsen T, Kongstad P, Borgesen SE. Traumatic brain damage: serum S-100 protein measurements related to neuroradiological findings. J Neurotrauma. 2000;17:473-477.
12. Haydel MJ, Preston CA, Mills TJ, et al. Indications for computed tomography in patients with minor head injury. N Engl J Med. 2000;343:100-105.
13. Stiell IG, Laupacis A, Wells GA. Indications for computed tomography after minor head injury. N Engl J Med. 2000;343:1570-1571.
14. Ibanez J, Arikan F, Pedraza S, et al. Reliability of clinical guidelines in the detection of patients at risk following mild head injury: results of a prospective study J Neurosurg. 2004;100:825-834.
15. Cabana MD, Rand CS, Powe NR, et al. Why don't physicians follow clinical practice guidelines? A framework for improvement. JAMA. 1999;282:1458-1465.
16. Ingebrigtsen T, Romner B. Routine early CT-scan is cost saving after minor head injury. Acta Neurol Scand. 1996;93:207-210.
17. Hall P, Adami HO, Trichopoulos D, et al. Effect of low doses of ionizing radiation in infancy on cognitive function in adulthood: Swedish population based cohort study. BMJ. 2004;328:19-21.
18. Undèn J, Bellner J, Eneroth M, et al. Raised serum S100B levels after acute bone fractures without cerebral injury. J Trauma. 2005;58:59-61.
19. Anderson RE, Hansson LO, Nilsson O, et al. High serum S100B levels for trauma patients without head injuries. Neurosurgery. 2001;48:1255-1258.
20. Jonsson H, Johnsson P, Hoglund P, et al. Elimination of S100B and renal function after cardiac surgery. J Cardiothorac Vasc Anesth. 2000;14:698-701.
21. Ytrebo LM, Nedredal GI, Korvald C, et al. Renal elimination of protein S-100beta in pigs with acute encephalopathy. Scand J Clin Lab Invest. 2001;61:217-225.
22. Ghanem G, Loir B, Morandini R, et al. On the release and half-life of S100B protein in the peripheral blood of melanoma patients. Int J Cancer. 2001;94:586-590.
23. Blomquist S, Johnsson P, Luhrs C, et al. The appearance of S-100 protein in serum during and immediately after cardiopulmonary bypass surgery: a possible marker for cerebral injury. J Cardiothorac Vasc Anesth. 1997;11:699-703.
24. Savola O, Pyhtinen J, Leino TK, et al. Effects of head and extracranial injuries on serum protein S100B levels in trauma patients. J Trauma. 2004;56:1229-1234.
25. Townend W, Dibble C, Abid K, et al. Rapid elimination of protein S-100B from serum after minor head trauma. J Neurotrauma. 2006;23:149-155.
26. Roy PM, Colombet I, Durieux P, et al. Systematic review and meta-analysis of strategies for the diagnosis of suspected pulmonary embolism. BMJ. 2005;331:259.
27. Undén J, Bellner J, Astrand R, Romner B. Serum S100B levels in patients with epidural haematomas. Br J Neurosurg. 2005;19:43-45.