Conversion of some 2(3H)-furanones bearing a pyrazolyl group into other heterocyclic systems with a study of their antiviral activity

European Journal of Medicinal Chemistry

Volumn 42, Issue 7, 2007, Pages 934-939

  Hashem, Ahmed I ^a   Youssef, Ahmed S A ^a   Kandeel, Kamal A ^a   Abou Elmagd, Wael S I ^a  

^a Ain Shams University   (Egypt)

Author keywords

1,2,4 Triazoles; 2(3H) Furanones; 2(3H) Pyrrolones; Antiviral activity; Viruses: HAV and HSV 1

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 1,3,4 OXADIAZOLE DERIVATIVE; 2 PHENYL 5 [3 AROYL 1 (1,3 DIPHENYLPYRAZOL 4 YL)] 2 PROPENYL 1,3,4 OXADIAZOLE; 2(3H)FURANONE DERIVATIVE; 3 (1,3 DIPHENYLPYRAZOL 4 YL METHYLENE) 5 ARYL 2(3H)FURANONE DERIVATIVE; 5 ARYL 4 (1,3 DIPHYENYLPYRAZOL 4 YLMETHYLENE)PYRIDAZIN 3 ONE; BENZYLAMINE; FURANONE DERIVATIVE; HETEROCYCLIC COMPOUND; HYDRAZINE; N BENZYLAMIDE DERIVATIVE; PYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL REACTION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN;

ANIMALS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; FURANS; HEPATITIS A VIRUS; HERPESVIRUS 1, HUMAN; MOLECULAR STRUCTURE; PLAQUE ASSAY; VERO CELLS;

EID: 34250325520     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.12.032     Document Type: Article

References (15)

1. Hashem A.I., Kandel K.A., Youssef A.S., and Abou El-magd W.S. J. Chem. Res. (2006) 315
2. Khan R.H., and Rastogi R.C. J. Chem. Res. (1991) 260
3. Hashem A.I. J. Prak. Chem. 321 (1979) 516
4. Yassin S., Abd El-Aleem A.H., El-Sayed I.E., and Hashem A.I. Collect. Czech. Chem. Commun. 58 (1993) 1925
5. Yassin S., Abd El-Aleem A.H., El-Sayed I.E., and Hashem A.I. Rev. Roum. Chem. 41 (1996) 989
6. Hashem A.I., and Shaban M.E. J. Prak. Chem. 323 (1981) 164
7. Hamad A.S., and Hashem A.I. J. Heterocycl. Chem. 39 (2002) 1325
8. El-Kousy S.M., Hashem A.I., El-Torgoman A., and Salama G.M. Afindad 503 (2003) 61
9. El-Gazwy A.S.H., Azki M.T., Eid N.N., and Hashem A.I. Heteroatom Chem. 14 6 (2003) 570
10. Meazza G., and Zanardi G. J. Heterocycl. Chem. 30 (1993) 365
11. Copp F.C., Islip P.J., and Tateson J.E. Biochem. Pharmacol. 33 (1988) 339
12. Bailey D.M., Hansen P.E., Hlarac A.G., Baizmen E.R., Pearl J., Defelico A.F., and Feigenson M.E. J. Med. Chem. 28 (1985) 265
13. Lee H.H., Cain B.F., Denny W.A., Bnckleron J.S., and Clark G.R. J. Org. Chem. 54 (1989) 428
14. Claramunt R.M., and Elguero J. Org. Prep. Proced. Int. 23 (1991) 273
15. Tebas P., Scholl D., Jollick J., Mc Harg K., Arens M., and Olivo P.D. J. Infect. Dis. 177 (1998) 217