Effects of targeting magnetic drug nanoparticles on human cholangiocarcinoma xenografts in nude mice

Hepatobiliary and Pancreatic Diseases International

Volumn 6, Issue 3, 2007, Pages 303-307

  Tang, Tao ^a   Zheng, Jian Wei ^a   Chen, Bo ^a   Li, Hong ^a   Li, Xi ^b   Xue, Ke Ying ^a   Ai, Xing ^a   Zou, Sheng Quan ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Cholangiocarcinoma; Magnetic nanoparticles; Nude mice; Targeting therapy

Indexed keywords

FLUOROURACIL; NANOPARTICLE; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BILE DUCT CARCINOMA; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER TRANSPLANTATION; CONTROLLED STUDY; DISEASE MODEL; DRUG DOSE COMPARISON; DRUG TARGETING; ELECTRON MICROSCOPY; GROWTH CURVE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; MOUSE; NANOTECHNOLOGY; NONHUMAN; NUDE MOUSE; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CHOLANGIOCARCINOMA; FLUOROURACIL; HUMANS; MAGNETICS; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; NEOPLASM TRANSPLANTATION; TRANSPLANTATION, HETEROLOGOUS;

EID: 34250303029     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Shi JS, Wang BH. Base and clinical of biliary tract surgery (the First Edition). The People Health Publish Group;2002: 674-691.
2. Khan SA, Davidson BR, Goldin R, Pereira SP, Rosenberg WM, Taylor-Robinson SD, et al. Guidelines for the diagnosis and treatment of cholangiocarcinoma: consensus document Gut 2002;51 Suppl 6:VI1-9.
3. Yalcin S. Diagnosis and management of cholangiocarcinomas: a comprehensive review. Hepatogastroenterology 2004;51:43-50.
4. Wiedmann M, Schoppmeyer K, Witzigmann H, Hauss J, Mossner J, Caca K. Current diagnostics and therapy for carcinomas of the biliary tree and gallbladder. Z Gastroenterol 2005;43:305-315.
5. Barrioz T. Medical management of cholangiocarcinoma. Gastroenterol Clin Biol 2004;28:57-65.
6. Freeman ML, Sielaff TD. A modern approach to malignant hilar biliary obstruction. Rev Gastroenterol Disord 2003;3: 187-201.
7. Otto G, Romaneehsen B, Hoppe-Lotichius M, Bittinger F. Hilar cholangiocarcinoma: resectability and radicality after routine diagnostic imaging. J Hepatobiliary Pancreat Surg 2004;11:310-318.
8. Rumalla A, Peterson BT. Diagnosis and therapy of biliary tract malignancy. Semin Gastrointest Dis 2000;11:168-173.
9. Xu M. Chemotherapy and countermeasure of malignancy (The first edition). Military Medicine Publishing Group; 2002:10-13.
10. Sanz-Altamira PM, Ferrante K, Jenkins RL, Lewis WD, Huberman MS, Stuart KE. A phase II otrial of 5-fluorouracil, leurorin and Carboplattio in patients with unresectable biliary tree carcinoma. Cancer 1998;82: 2331-2335.
11. Roco MC. Nanotechnology: convergence with modern biology and medicine. Curr Opin Biotechnol 2003;14:337-346.
12. Li AM, Zhang CX, Fu XP, Zhang ZW, Xue QH, Yan RM, et al. Localization and distribution of magnetic chemotherapeutic drugs with magnetic targeting in rat brain. Chin Med J (Engl) 2005;118:824-827.
13. Jacob G, Rotariu O, Stracchan NJ, Hafeli UO. Magnetizable needles and wires-modeling an efficient way to target magnetic microspheres in vivo. Biorheology 2004;41:599-612.
14. Hafeli UO. Magnetically modulated therapeutic systems. Int J Pharm 2004;277:19-24.
15. Fiehn C, Muller-Ladner U, Gay S, Krienke S, Freudenberg-Konrad S, Funk J, et al. Albumin-coupled methotrexate (MTX-HSA) is a new anti-arthritic drug which acts synergistically to MTX. Rheumatology 2004;43:1097-1105.
16. Alexiou C, Jurgons R, Schmid RJ, Bergemann C, Henke J, Erhardt W. Magnetic drug targeting-biodistribution of the magnetic carrier and the chemotherapeutic agent mitoxantrone after locoregional cancer treatment. J Drug Target 2003;11:139-149.
17. Menon D, Karyekar CS, Fasano A, Lu R, Eddington ND. Enhancement of brain distribution of anticancer agents using DeltaG, the 12 kDa active fragment of ZOT. Int J Pharm 2005;306:122-131.
18. Yamane N, Makino M, Kaibarn N. S-phase accumulation precedes apoptosis induced by preoperative treatment with 5-fluorouracil in human colorectal carcinoma cells. Cancer 1999;85:309-317.
19. Backus HH, Dukers DF, van Groeningen CJ, Vos W, Bloemena E, Wouters D, et al. 5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients. Ann Oncol 2001;12:209-216.
20. Massari D, Trobonjac Z, Rukavina D, Radosevic-Stasic B. SMS 201-995 enhances S-phase block induced by 5-fluorouracil in a human colorectal cancer cell line. Anticancer Drugs 2005;16:989-996.
21. Kawai K, Watabe S, Matsuda M, Sakamoto K, Kamano T. Correlation between expression of orotate phosphoribosyl transferase and 5-fluorouracil sensitivity, as measured by apoptosis index in colorectal cancer tissue. Int J Gastrointest Cancer 2005;35:197-203.
22. Pulfer SK, Ciccoto SL, Gallo JM. Distribution of small magnetic particles in brain tumor-bearing rats. J Nurooncol 1999;41:99-105.
23. Senyei AE, Reich SD, Goczy C, Widder KJ. In vivo kinetics of magnetically targeted low-dose doxoruicin. J Pharm Sci 1981;70:389-391.
24. Wu Y, Wang JL, Ye HJ. The delay release function of mitomycin C polycarbonate magnetic microsphere and its role on treat transplant hepatocarcinoma. Chin J Dig 2001; 21:691-693.
25. Lind K, Kresse M, Debus NP, Muller RH A novel formulation for superparamagnetic iron oxide (SPIO) particles enhancing MR lymphography: comparison of physicochemical properties and the in vivo behaviour. J Drug Target 2002;10:221-230.
26. Jain S, Mishra V, Singh P, Dubey PK, Saraf DK, Vyas SP. RGD-anchored magnetic liposomes for monocytes/neutrophils-mediated brain targeting. Int J Pharm 2003; 261:43-55.
27. Chen X, Hou Y, Tohme M, Park R, Khankaldyyan V, Gonzales-Gomez I, et al. Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor alphavbeta3-integrin expression. J Nucl Med 2004;45:1776-1783.
28. Muvaffak A, Gurhan I, Gunduz U, Hasirci N. Preparation and characterization of a biodegradable drug targeting system for anticancer drug delivery: microsphere-antibody conjugate. J Drug Target 2005;13:151-159.
29. Pan GY, Liu XD, Liu GQ. Intracarotid infusion of hypertonic mannitol changes permeability of blood-brain barrier to methotrexate in rats. Acta Pharmacol Sin 2000; 21:613-616.
30. Liang LS, Wong W, Burt HM. Pharmacokinetic study of methotrexate following intra-articular injection of methotrexate loaded poly (L-lactic acid) microspheres in rabbits. J Pharm Sci 2005;94:1204-1215.
31. Driscoll CF, Morris RM, Senyei AE, Widder KJ, Heller GS. Magnetic targeting of microspheres in blood flow. Microvas Res 1984;27:353-369.