Genotoxicity of novel trans-platinum(II) complex with diethyl (pyridin-4-ylmethyl)phosphate in human non-small cell lung cancer cells A549

Chemico-Biological Interactions

Volumn 168, Issue 2, 2007, Pages 135-142

  Matlawska Wasowska, Ksenia ^a   Rainczuk, Katarzyna ^a   Kalinowska Lis, Urszula ^b   Osiecka, Regina ^a   Ochocki, Justyn ^b  

^a UNIVERSITY OF LODZ   (Poland)

^b MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

cis Diamminedichloroplatinum(II); Comet assay; DNA damage; DNA protein cross links; Pyridine derivatives; trans Platinum(II) complexes

Indexed keywords

CISPLATIN; DIETHYL(PYRIDIN 4 YLMETHYL)PHOSPHATE; PHOSPHATE; PROTEINASE K; TRANSPLATIN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CANCER CELL; COMET ASSAY; CONTROLLED STUDY; CROSS LINKING; DNA DAMAGE; DNA STRAND BREAKAGE; GENOTOXICITY; GEOMETRY; HUMAN; HUMAN CELL; INCUBATION TIME; LUNG NON SMALL CELL CANCER;

CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL SURVIVAL; COMET ASSAY; DNA DAMAGE; DNA REPAIR; DNA, NEOPLASM; HUMANS; LUNG NEOPLASMS; ORGANOPLATINUM COMPOUNDS; PHOSPHORIC ACID ESTERS; TRYPAN BLUE;

EID: 34250202240     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2007.04.001     Document Type: Article

References (34)

1. Rosenberg B., Van Camp L., and Crigas T. Inhibition of cell division in Escherichia coli by electrolysis products from platinum electrode. Nature 205 (1965) 698-699
2. Lebwohl D., and Canetta R. Clinical development of platinum complexes in cancer therapy: an historical perspectives and an update. Eur. J. Cancer. 34 (1998) 1522-1534
3. Kelland L.R., Sharp S.Y., O'Neill C.F., Raynaud F.I., Beale P.J., and Judson I.R. Mini-review: discovery and development of platinum complexes designed to circumvent cisplatin resistance. J. Inorg. Biochem. 77 (1999) 111-115
4. Desoize B., and Madoulet C. Particular aspects of platinum compounds used at present in cancer tereatment. Crit. Rev. Oncol./Hematol. 42 (2002) 317-325
5. Radulovic S., Tescic Z., and Manic S. trans-Platinum complexes as anticancer drugs: recent development and future prospects. Curr. Med. Chem. 9 (2002) 1611-1618
6. Natile G., and Collucia M. Current status of trans-platinum compounds in cancer therapy. Coor. Chem. Rev. 216-217 (2001) 383-410
7. Farell N., Ha T.T.B., Souchard J.P., Wimmer F.L., Cros S., and Johnson N.P. Cytostatic trans-platinum(II) complexes. J. Med. Chem. 32 (1989) 2240-2241
8. Farrel N., Kelland L.R., Roberts J.D., and Von Beusichem M. Activation of the trans geometry in platinum antitumor complexes: a survey of the cytotoxicity of trans complexes containing planar ligands in murine L1210 and human tumor panels and studies on their mechanism of action. Cancer Res. 18 (1992) 5065-5072
9. Kelland L.R., Barnard C.F.J., Evans I.G., Murrer B.A., Theobald B.R.C., Wyer S.B., Goddard P.M., Jones M., Valenti M., Bryant A., Rogers P.M., and Harrap K.R. Synthesis and in vitro and in vivo antitumor activity of a series of trans platinum antitumor complexes. J. Med. Chem. 38 (1995) 3016-3024
10. 3(4-hydroxymethyl)-pyridine)]. Polyhedron 22 (2003) 3379-3381
11. Perez J.M., Fuertes M.A., Alonso C., and Navarro-Ranninger C. Current status of development of trans-platinum antitumor drugs. Crit. Rev. Oncol./Hematol. 35 (2001) 120-190
12. Farell N., Povirk L.F., Dange Y., DeMasters G., Gupta M.S., Kohlhagen G., Khan Q.A., Pommier Y., Gewirtz D.A., and Cytotoxicity. DNA strand brakage and DNA-protein crosslinking by a novel transplatinum compound in human A2780 ovarian and MCF-7 breast carcinoma cells. Biochem. Pharmacol. 68 (2004) 857-866
13. 3)L] (L = planar nitrogen base). Effect of L and cis/trans isomerism on Sequence specificity and unwinding properties observed in globally platinated DNA. Inorg. Chem. 38 (1999) 3535-3542
14. Kalinowska U., Matlawska K., Checinska L., Domagala M., Kontek R., Osiecka R., and Ochocki J. Synthesis, spectroscopy and antiproliferative activity of cis- and trans-platinum(II) complexes with diethyl (pyridin-4-ylmethyl)phosphate. X-ray crystal structure of trans-Pt(II) complex. J. Inorg. Biochem. 99 (2005) 2024-2031
15. Rojas E., Lopez M.C., and Valverde M. Single cell gel electrophoresis assay: methodology and applications. J. Chromat. 722 (1999) 225-254
16. Kassie F., Parzefall W., and Knasmuller S. Single cell gel electrophoresis assay: a new technique for human biomonitoring studies. Mutat. Res. 463 (2000) 13-31
17. Singh N.P., McCoy T., Tice R.R., and Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell. Res. 175 (1998) 184-192
18. Konca K., Lankoff A., Banasik A., Lisowska H., Kuszewski T., Gozdz S., and Koza Z. A cross platform public domain PC image-analysis program for the comet assay. Mutat. Res. 534 (2003) 15-20
19. Wozniak K., and Blasiak J. In vitro genotoxicity of lead acetate: induction of single and double DNA strand breaks and DNA-protein cross-links. Mutat. Res. 535 (2003) 127-139
20. Merk O., Reiser K., and Speit G. Analysis of chromate-induced DNA-protein crosslinks with the comet assay. Mutat. Res. 471 (2000) 71-80
21. Hartmann A., Kiskinis E., Fjallman A., and Suter W. Influence of cytotoxicity and compound precipitation on test results in the alkaline comet assay. Mutat. Res. 497 (2001) 199-212
22. Kelland L.R., Barnard C.F.J., Mellish K.J., Jones M., Goddard P.M., Valenti M., Bryant A., Murrer B.A., and Harrap K.R. A novel trans-platinum coordination complex possessing in vitro and in vivo antitumor activity. Cancer Res. 54 (1994) 5618-5622
23. Kosmider B., Zyner E., Osiecka R., and Ochocki J. Genotoxicity of cis-Pt(II) complex of aminoflavone in comparison with cis-DDP in A549 cells evaluated by comet assay. Can. J. Physiol. Pharmacol. 82 (2004) 353-358
24. Ciesielska E., Studzian K., Zyner E., Ochocki J., and Szmigiero L. DNA damage and apoptosis induction in L1210 cells by cis-diamminedichloroplatinum(II) and its new aminoflavone analogue. Cell. Mol. Biol. Lett. 5 (2000) 441-450
25. Wozniak K., Czechowska A., and Blasiak J. Cisplatin-evoked fragmentation in normal and cancer cells and its modulation by free radical scavengers and tyrosine kinase inhibitor STI571. Chem. Biol. Interact. 147 (2004) 309-318
26. Wozniak K., and Blasiak J. Recognition and repair of DNA-cisplatin adducts. Acta Biochim. Pol. 49 (2002) 583-596
27. Malinge J.M., Giraud-Panis M.J., and Leng M. Interstrand cross-links of cisplatin induce striking distoritions in DNA. J. Inorg. Bioch. 77 (1999) 23-29
28. Duthie S.J., Collins A.R., Duthie G.G., and Dobson V.L. Quercetin and myricetin protect against hydrogen peroxide-induced DNA damage (strand breaks and oxidized pyrimidines) in human lymphocytes. Mutat. Res. 393 (1997) 223-231
29. Kindzelskii A.L., and Petty H.R. Ultrasenstive detection of hydrogen peroxide-mediated DNA damage after alakaline single cell gel electrophoresis using occulation microscopy and TUNEL labeling. Mutat. Res. 426 (1999) 11-22
30. 2 and γ-irradiation with the alkaline comet assay. Mutat. Res. 383 (1997) 71-80
31. Gasiorowski K., and Brokos B. DNA repair of hydrogen peroxide-induced damage in human lymphocytes in the presence of four antimutagens. A study with alkaline single cell gel electhrophoresis (comet assay). Cell. Mol. Biol. Lett. 6 (2001) 897-911
32. Blasiak J., Trzeciak A., Malecka-Panas E., Drzewoski J., and Wojewodzka M. In vitro genotoxicity of etanol and acetaldehyde in human lymphocytes and the gastrointestinal tract mucosa cells. Toxicol. In Vitro 14 (2000) 287-295
33. 2]. A concept for activation of the trans geometry in platinum antitumor complexes. Nucleic Acids Res. 31 (2003) 6450-6460
34. Brabec V., Neplechova K., Kasparkova J., and Farell N. Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonleaving groups. J. Biol. Inorg. Chem. 5 (2000) 364-368