Diverse regulatory activity of human heat shock proteins 60 and 70 on endotoxin-induced inflammation

Biochemical and Biophysical Research Communications

Volumn 359, Issue 3, 2007, Pages 709-715

  Bangen, Jörg M ^a   Schade, F Ulrich ^a   Flohé, Stefanie B ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Heat shock proteins; Lipopolysaccharide; Monocytes; TLR4; TNF

Indexed keywords

ENDOTOXIN; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; INFLAMMATION; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIGENS, CD14; CELLS, CULTURED; CHAPERONIN 60; ENDOTOXINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MONOCYTES; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS);

EID: 34250199032     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.05.167     Document Type: Article

References (19)

1. Hashiguchi N., Ogura H., Tanaka H., Koh T., Aoki M., Shiozaki T., Matsuoka T., Shimazu T., and Sugimoto H. Enhanced expression of heat shock proteins in leukocytes from trauma patients. J. Trauma 50 (2001) 102-107
2. Flohé S.B., Bangen J.M., Flohé S., Agrawal H., Bergmann K., and Schade F.U. Origin of immunomodulation after soft tissue trauma: potential involvement of extracellular heat-shock proteins. Shock 27 (2007) 494-502
3. Flohé S.B., Bruggemann J., Lendemans S., Nikulina M., Meierhoff G., Flohé S., and Kolb H. Human heat shock protein 60 induces maturation of dendritic cells versus a Th1-promoting phenotype. J. Immunol. 170 (2003) 2340-2348
4. Asea A., Kraeft S.K., Kurt-Jones E.A., Stevenson M.A., Chen L.B., Finberg R.W., Koo G.C., and Calderwood S.K. HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat. Med. 6 (2000) 435-442
5. Wang R., Kovalchin J.T., Muhlenkamp P., and Chandawarkar R.Y. Exogenous heat shock protein 70 binds macrophage lipid raft microdomain and stimulates phagocytosis, processing, and MHC-II presentation of antigens. Blood 107 (2006) 1636-1642
6. Bianchi M.E. DAMPs, PAMPs and alarmins: all we need to know about danger. J. Leukoc. Biol. 81 (2007) 1-5
7. Gao B., and Tsan M.F. Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages. J. Biol. Chem. 278 (2003) 22523-22529
8. Bausinger H., Lipsker D., Ziylan U., Manie S., Briand J.P., Cazenave J.P., Muller S., Haeuw J.F., Ravanat C., de la Salle H., and Hanau D. Endotoxin-free heat-shock protein 70 fails to induce APC activation. Eur. J. Immunol. 32 (2002) 3708-3713
9. Osterloh A., Kalinke U., Weiss S., Fleischer B., and Breloer M. Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide. J. Biol. Chem. 282 (2007) 4669-4680
10. Basu S., Binder R.J., Suto R., Anderson K.M., and Srivastava P.K. Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway. Int. Immunol. 12 (2000) 1539-1546
11. Habich C., Kempe K., van der Zee R., Rumenapf R., Akiyama H., Kolb H., and Burkart V. Heat shock protein 60: specific binding of lipopolysaccharide. J. Immunol. 174 (2005) 1298-1305
12. Arnold-Schild D., Hanau D., Spehner D., Schmid C., Rammensee H.G., de la Salle H., and Schild H. Cutting edge: receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells. J. Immunol. 162 (1999) 3757-3760
13. Yoo C.G., Lee S., Lee C.T., Kim Y.W., Han S.K., and Shim Y.S. Anti-inflammatory effect of heat shock protein induction is related to stabilization of I kappa B alpha through preventing I kappa B kinase activation in respiratory epithelial cells. J. Immunol. 164 (2000) 5416-5423
14. Jiang Q., Akashi S., Miyake K., and Petty H.R. Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. J. Immunol. 165 (2000) 3541-3544
15. Cuschieri J., Billigren J., and Maier R.V. Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: a condition reversed by PKC activation. J. Leukoc. Biol. 80 (2006) 1289-1297
16. Kilmartin B., and Reen D.J. HSP60 induces self-tolerance to repeated HSP60 stimulation and cross-tolerance to other pro-inflammatory stimuli. Eur. J. Immunol. 34 (2004) 2041-2051
17. Aneja R., Odoms K., Dunsmore K., Shanley T.P., and Wong H.R. Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells. J. Immunol. 177 (2006) 7184-7192
18. Kustanova G.A., Murashev A.N., Karpov V.L., Margulis B.A., Guzhova I.V., Prokhorenko I.R., Grachev S.V., and Evgen'ev M.B. Exogenous heat shock protein 70 mediates sepsis manifestations and decreases the mortality rate in rats. Cell Stress Chaperones 11 (2006) 276-286
19. Davies E.L., Bacelar M.M., Marshall M.J., Johnson E., Wardle T.D., Andrew S.M., and Williams J.H. Heat shock proteins form part of a danger signal cascade in response to lipopolysaccharide and GroEL. Clin. Exp. Immunol. 145 (2006) 183-189