Activation of extracellular-signal-regulated kinase-1/2 precedes and is required for injury-induced Schwann cell proliferation

NeuroReport

Volumn 18, Issue 10, 2007, Pages 957-961

  Mårtensson, Lisa ^a   Gustavsson, Per ^a   Dahlin, Lars B ^b   Kanje, Martin ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cellular proliferation; Erk map kinases; Nerve injury; Nerve regeneration; Phosphorylation; Schwann cells

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BROXURIDINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; IMMUNOHISTOCHEMISTRY; NERVE CELL CULTURE; NERVE FIBER TRANSECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SCHWANN CELL; SCIATIC NERVE;

EID: 34250192938     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNR.0b013e32819f8f27     Document Type: Article

References (22)

1. Terenghi G. Peripheral nerve regeneration and neurotrophic factors. J Anat 1999; 194:1-14.
2. Koeppen AH. Wallerian degeneration: history and clinical significance. J Neurol Sci 2004; 220:115-117.
3. Hall SM. The effect of inhibiting Schwann cell mitosis on the reinnervation of acellular autografts in the peripheral nervous system of the mouse. Neuropath Appl Neurobiol 1986; 12:401-414.
4. Berti-Mattera LN, Wilkins PL, Harwalkar S, Madhun Z, Almhanna K, Mattera R. Endothelins regulate arachidonic acid release and mitogen-activated protein kinase activity in Schwann cells. J Neurochem 2000; 75:2316-2326.
5. Reynolds AJ, Hendry IA, Bartlett SE. Anterograde and retrograde transport of active extracellular signal-related kinase 1 (ERK1) in the ligated rat sciatic nerve. Neuroscience 2001; 105:761-771.
6. Delcroix J-D, Valetta JS, Wu C, Hunt SJ, Kowal AS, Mobley WC. NGF signalling in sensory neurons: evidence that early endosomes carry NGF retrograde signals. Neuron 2003; 39:69-84.
7. Tapinos N, Rambukkana A. Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprocy bacilli. Proc Natl Acad Sci USA 2005; 102:9188-9193.
8. Segal RA, Greenberg ME. Intracellular signalling pathways activated by neurotrophic factors. Annu Rev Neurosci 1996; 19:463-489.
9. Abe K, Namikawa K, Honma M, Iwata T, Matsouka I, Watabe K, Kiyama H. Inhibition of Ras extracellular-signal-regulated kinase (ERK) mediated signalling promotes ciliary neurotrophic factor (CNTF) expression in Schwann cells. J Neurochem 2001; 77:700-703.
10. Sheu JY, Kulhanek DJ, Eckenstein FP. Differential patterns of ERK and STAT3 phosphorylation after sciatic nerve transection in the rat. Exp Neurol 2000; 166:392-402.
11. Agthong S, Kaewsema A, Tanomsridejchai N, Chentanez V. Activation of MAPK ERK in peripheral nerve after injury. BMC Neurosci 2006; 7:45.
12. Harrisingh MC, Perez-Nadales E, Parkinson DB, Malcolm DS, Mudge AW, Lloyd AC. The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation. EMBO J 2004; 23:3061-3071.
13. Lindwall C, Dahlin L, Lundborg G, Kanje M. Inhibition of c-Jun phosphorylation reduces axonal outgrowth of adult rat nodose ganglia and dorsal root ganglia sensory neurons. Mol Cell Neurosci 2004; 27: 267-279.
14. 2+-dependent signal pathways in rat-1 cells. J Biol Chem 1997; 272:13309-13319.
15. Sondell M, Fex-Svenningsen Å, Kanje M. The insulin-like growth factors I and II stimulate proliferation of different types of Schwann cells. Neuroreport 1997; 8:2871-2876.
16. Biesiada E, Razandi M, Levin ER. Egr-1 activates basic fibroblast growth factor transcription. J Biol Chem 1996; 271:18576-18581.
17. Yun MS, Kim SE, Jeon SH, Lee JS, Choi KY. Both ERK and Wnt/β-catenin pathways are involved in Wnt3a-induced proliferation. J Cell Sci 2004; 118:313-322.
18. Monje PV, Bunge MB, Wood PM. Cyclic AMP synergestically enhances Neuregulin-dependent ERK and Akt activation and cell cycle progression in Schwann cells. Glia 2006; 53:649-659.
19. Averill S, Delcroix J-D, Michael GJ, Tomlinsson DR, Fernyhough P, Priestley JV. Nerve growth factor modulates the activation status and fast axonal transport of ERK 1/2 in adult nociceptive neurones. Mol Cell Neurosci 2001; 18:183-196.
20. Perlson E, Hanz S, Ben-Yaakov K, Segal-Ruder Y, Seger R, Fainzilber M. Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron 2005; 45:715-726.
21. Wiklund P, Ekström PAR, Edström A. Mitogen-activated protein kinase inhibition reveals differences in signalling pathways activated by neurotrophin-3 and other growth-stimulating conditions of adult mouse dorsal root ganglia neurons. J Neurosci Res 2002; 67:62-68.
22. Liu R-Y, Snider WD. Different signaling pathways mediate regenerative versus developmental sensory axon growth. J Neurosci 2001; 21:RC164.