Measurement of fluorophore concentration in turbid media by a single optical fiber

Medical Laser Application

Volumn 22, Issue 1, 2007, Pages 23-34

  Stepp, Herbert ^a   Beck, Tobias ^a   Beyer, Wolfgang ^a   Pfaller, Christian ^a   Schuppler, Matthias ^a   Sroka, Ronald ^a   Baumgartner, Reinhold ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Fiberoptic fluorescence sensor; Fluorescence quantification; Fluorescence spectroscopy; Fluorochrome concentration; Photodynamic therapy; Tissue optical properties

Indexed keywords

CONCENTRATION (PROCESS); FLUORESCENCE SPECTROSCOPY; MONTE CARLO METHODS; OPTICAL FIBERS; PHOTODYNAMIC THERAPY; PHOTOSENSITIZERS; TUMORS; TURBIDITY;

FIBEROPTIC FLUORESCENCE SENSORS; FLUORESCENCE QUANTIFICATION; OPTICAL PARAMETERS; TISSUE OPTICAL PROPERTIES;

FLUOROPHORES;

EID: 34250187760     PISSN: 16151615     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mla.2006.08.005     Document Type: Article

References (10)

1. Thompson M.S., Johansson A., Johansson T., Andersson-Engels S., Svanberg S., et al. Clinical system for interstitial photodynamic therapy with combined on-line dosimetry measurements. Appl Opt 44 19 (2005) 4023-4031
2. Stepp H., Beck T., Beyer W., Pongratz T., Sroka R., Baumgartner R., et al. Fluorescence-guided resections and photodynamic therapy for malignant gliomas using 5-aminolevulinic acid. Proceedings of the SPIE 5686 (2005) 547-557
3. Lilge L., O'Carroll C., and Wilson B.C. A solubilization technique for photosensitizer quantification in ex vivo tissue samples. J Photochem Photobiol B 39 3 (1997) 229-235
4. Lee C.C., Pogue B.W., Strawbridge R.R., Moodie K.L., Bartholomew L.R., Burke G.C., et al. Comparison of photosensitizer (AIPcS2) quantification techniques: in situ fluorescence microsampling versus tissue chemical extraction. Photochem Photobiol 74 3 (2001) 453-460
5. Pogue B.W., and Burke G.C. Fiber-optic bundle design for quantitative fluorescence measurement from tissue. Appl Opt 37 31 (1998) 7429-7436
6. Weersink R.A., Patterson M.S., Diamond K.R., Silver S., and Padgett N. Noninvasive measurement of fluorophore concentration in turbid media with a simple fluorescence/reflectance ratio technique. Appl Opt 40 34 (2001) 6389-6395
7. Diamond K.R., Malysz P.P., Hayward J.E., and Patterson M.S. Quantification of fluorophore concentration in vivo using two simple fluorescence-based measurement techniques. J Biomed Opt 10 2 (2005) 024007
8. Diamond K.R., Patterson M.S., and Farrell T.J. Quantification of fluorophore concentration in tissue-simulating media by fluorescence measurements with a single optical fiber. Appl Opt 42 13 (2003) 2436-2442
9. Prahl S.A., Keijzer M., Jacques S.L., and Welch A.J. A Monte Carlo model of light propagation in tissue. SPIE Institute Series IS 5 1989, 102-111 (2006)
10. Bargo P.R., Prahl S.A., and Jacques S.L. Collection efficiency of a single optical fiber in turbid media. Appl Opt 42 16 (2003) 3187-3197