The application of small porous particles, high temperatures, and high pressures to generate very high resolution LC and LC/MS separations

Journal of Separation Science

Volumn 30, Issue 8, 2007, Pages 1158-1166

  Plumb, Robert ^a   Mazzeo, Jeff R ^a   Grumbach, Eric S ^a   Rainville, Paul ^a   Jones, Michael ^a   Wheat, Tom ^a   Neue, Uwe D ^a   Smith, Brian ^a   Johnson, Kally A ^a  

^a Pharmaceutical Application and Development Manager   (United States)

Author keywords

Efficiency; High pressure; HPLC; Temperature

Indexed keywords

ANALYTE RETENTION; CHROMATOGRAPHIC EFFICIENCY; EXOTIC ORGANIC MODIFIERS; HIGH RESOLUTION MASS SPECTROMETERS; OPTIMAL MOBILE PHASE LINEAR VELOCITY;

CATALYST SELECTIVITY; HIGH PRESSURE EFFECTS; HIGH TEMPERATURE EFFECTS; SEPARATION; VISCOSITY;

LIQUID CHROMATOGRAPHY;

2 ACETOMIDOPHENOL; 2 PROPANOL; ACETANILIDE; ACETONITRILE; ACETYLSALICYLIC ACID; ANALGESIC AGENT; CAFFEINE; GINSENG EXTRACT; METHANOL; PARACETAMOL; PHENACETIN; SALICYLIC ACID; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; CONTROLLED STUDY; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH TEMPERATURE; LINEAR SYSTEM; PARTICLE SIZE; POROSITY; PRESSURE MEASUREMENT; PRIORITY JOURNAL; PRODUCTIVITY; QUALITY CONTROL; TIME; TIME OF FLIGHT MASS SPECTROMETRY; VELOCITY; VISCOSITY;

CHROMATOGRAPHY, LIQUID; MASS SPECTROMETRY; PARTICLE SIZE; POROSITY; PRESSURE; SENSITIVITY AND SPECIFICITY; TEMPERATURE;

EID: 34250186446     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200600492     Document Type: Article

References (28)

1. MacNair, J. E., Lewis, K. C., Jorgenson, J. W., Anal. Chem. 1997, 69, 983-989.
2. MacNair, J. E., Kamlesh, D. P., Jorgenson, J. W., Anal. Chem. 1999, 71, 700-708.
3. Tolley, L., Jorgenson, J. W., Moseley, M. A., Anal. Chem. 2001, 73, 2985-2991.
4. Mellors, J. S., Jorgenson, J. W., Anal. Chem. 2004, 76, 5441-5450.
5. MacNair, J. E., Patel, K. D., Jorgenson, J. W., Anal. Chem. 1999, 71, 700-708.
6. Wu, N., Lippert, J. A., Lee, M. L., J. Chromatogr. A 2001, 911, 1-12.
7. Patel, K. D., Jerkovich, A. D., Link, J. C., Jorgenson, J. W., Anal. Chem. 2004, 76, 5777-5786.
8. Colon, L. A., Cintron, J. M., Anspach, J. A., Fermier, A. M., Swinney, K. A., Analyst 2004, 129, 503-504.
9. de Villiers, A., Lauer, H., Szucs, R., Goodall, S., Sandra, P., J. Chromatogr. A 2006, 1113, 84-91.
10. Lestremau, F., Cooper, A., Szucs, R., David, F., Sandra, P., J. Chromatogr. A 2006, 1109, 191-196.
11. Antia, F. D., Horvath, C., J. Chromatogr. 1988, 435, 1-15.
12. Wang, X., Barber, W. E., Carr, P. W., J. Chromatogr. A 2006, 1107, 139-151.
13. Wang, Y., Liu, Y., Lee, M. L., J. Chromatogr. A 2006, 1104, 198-202.
14. Swartz, M., LabPlus International 2004, 18, 6-9.
15. Mazzeo, J. R., Neue, U. D., Kele, M., Plumb, R. S., Anal. Chem. 2005, 77, 460A-467A.
16. Frank, M., Gratzfeld-Huesgen, A., Schuette, S., Am. Lab. 2006, 38, 17-22.
17. Li, R., Dong, L., Huang, J., Anal. Chim. Acta 2005, 546, 167-173.
18. Wrona, M., Mauriala, T., Bateman, K. P., Mortishire-Smith, R. J., O'Connor, D., Rapid Comm. Mass Spec. 2005, 19, 2597-2602.
19. Lurie, I. S., J. Chromatogr. A 2005, 1100, 168-175.
20. Kaufmann, A., Butcher, P., Rapid Comm. Mass Spec. 2005, 19, 3694-3700.
21. Nielen, M. W., Bovee, T. F., van Engelen, M. C., Rutgers, P. et al., Anal. Chem. 2006, 78, 424-431.
22. Bendahl, L., Hansen, S. H., Gammelgaard, B., Sturup, S., Nielsen, C., J. Pharm. Biomed. Anal. 2006, 40, 571-580.
23. Shen, J. X., Wang, H., Tadros, S., Hayes, R. N., J. Pharm. Biomed. Anal. 2006, 40, 689-706.
24. Mezcua, M., Aguera, A., Lliberia, J. L., Cortes, M. A. et al., J. Chromatogr. A 2006, 1109, 222-227.
25. Appolonio, L. G., Pianca, D. J., Whittall, I. R., Maher, W. A., Kyd, J. M., J. Chromatogr. B 2006, 836, 111-115.
26. Wilke, C. R., Chang, P., AICHE J. 1955, 1, 264-270.
27. Scheibel, E. G., Ind. Eng. Chem. 1954, 46, 2007-2008.
28. Liu, Y., Grinberg, N., Thompson, K. C., Wenslow, R. M. et al., Anal. Chim. Acta 2005, 554, 144-151.