Caught after the act: A human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide

Biochemistry

Volumn 46, Issue 23, 2007, Pages 6921-6930

  Bayés, Àlex ^a   Fernández, Daniel ^a   Solà, Maria ^b   Marrero, Aniebrys ^b   García Piqué, Sonia ^b   Avilés, Francesc X ^a   Vendrell, Josep ^a   Xavier Gomis Ruth F ^b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE MECHANISM; PROTEOLYTIC ENZYMES;

BINDING ENERGY; CATALYST ACTIVITY; MOLECULAR STRUCTURE; POLYPEPTIDES; PROTEINS;

ENZYME INHIBITION;

CARBOXYPEPTIDASE A; CARBOXYPEPTIDASE B; GLOBULAR PROTEIN; HEXAPEPTIDE; METALLOCARBOXYPEPTIDASE; METALLOCARBOXYPEPTIDASE A; METALLOCARBOXYPEPTIDASE A4; METALLOCARBOXYPEPTIDASE B; METALLOPROTEINASE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY;

AMINO ACID SEQUENCE; CARBOXYPEPTIDASE B; CARBOXYPEPTIDASES A; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PROTEIN CONFORMATION;

EID: 34250185374     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700480b     Document Type: Article

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