Treatment of refractory blistering autoimmune diseases with mycophenolic acid

Journal of Dermatological Treatment

Volumn 17, Issue 6, 2006, Pages 370-376

  Marzano, Angelo V ^a   Dassoni, Federica ^a   Caputo, Ruggero ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Blistering autoimmune diseases; Enteric coated mycophenolate sodium; Mycophenolate mofetil; Mycophenolic acid

Indexed keywords

BETAMETHASONE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RITUXIMAB;

ABDOMINAL DISCOMFORT; ADULT; AGED; ARTICLE; ASTHENIA; AUTOIMMUNE DISEASE; BLISTER; BLOOD ANALYSIS; BULLOUS SKIN DISEASE; CANCER; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DISEASE ASSOCIATION; DRUG COATING; DRUG DOSAGE FORM COMPARISON; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG DOSE SEQUENCE; DRUG EFFICACY; DRUG FORMULATION; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; EPIDERMOLYSIS BULLOSA ACQUISITA; FEMALE; GASTROINTESTINAL SYMPTOM; HERPES ZOSTER; HUMAN; MALE; MONOTHERAPY; MUCOUS MEMBRANE PEMPHIGOID; NON INSULIN DEPENDENT DIABETES MELLITUS; PEMPHIGUS VULGARIS; PRIORITY JOURNAL; RELAPSE; REMISSION; SIDE EFFECT; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; AGED; AGED, 80 AND OVER; AUTOIMMUNE DISEASES; DERMATOLOGIC AGENTS; ENZYME INHIBITORS; FEMALE; GLUCOCORTICOIDS; HUMANS; MALE; MIDDLE AGED; MYCOPHENOLIC ACID; SKIN DISEASES, VESICULOBULLOUS; TREATMENT OUTCOME;

EID: 34250184467     PISSN: 09546634     EISSN: 14711753     Source Type: Journal    
DOI: 10.1080/09546630600964999     Document Type: Article

References (17)

1. Lipsky J. Mycophenolate mofetil. Lancet. 1996;348:1357-9.
2. Liu V, Mackool BT. Mycophenolate in dermatology. J Dermatol Treat. 2003;14:203-11.
3. Budde K, Curtis J, Knoll G, Chan L, Neumayer HH, Seifu Y, et al. Enteric-coated mycophenolate sodium can be safely administered in maintenance renal transplant patients: Results of a 1-year study. Am J Transplant. 2004;4:237-43.
4. Ikeda S, Imamura S, Hashimoto I, Morioka S, Sakuma M, Ogawa H. History of the establishment and revision of diagnostic criteria, severity index and therapeutic guidelines for pemphigus in Japan. Arch Dermatol Res. 2003;295:S12-16.
5. Allison AC, Eugui EM. Purine metabolism and the immunosuppressive effects of mycophenolate mofetil (MMF). Clin Transplant. 1996;10:77-84.
6. Nousari HC, Sragovich A, Kimyai-Asadi A, Orlinsky D, Anhalt GJ. Mycophenolate mofetil in autoimmune and inflammatory skin disorders. J Am Acad Dermatol. 1999;40:265-8.
7. Mimouni MD, Anhalt GJ, Cummins DL, Kouba DJ, Thorne JE, Nousari HC. Treatment of pemphigus vulgaris and pemphigus foliaceus with mycophenolate mofetil. Arch Dermatol. 2003;139:739-42.
8. Salopek TG, Logsetty S, Tredget EE. Anti-CD20 chimeric monoclonal antibody (rituximab) for the treatment of recalcitrant, life-threatening pemphigus vulgaris with implications in the pathogenesis of the disorder. J Am Acad Dermatol. 2002;47:785-8.
9. Bredlich RO, Grundmann-Kollman M, Behrens S, Kerscher M, Peter RU. Mycophenolate mofetil monotherapy for pemphigus vulgaris. Br J Dermatol. 1999;141:934.
10. Grundmann-Kollman M, Korting HC, Behrens S, Kaskel P, Leiter U, Krahn G, et al. Mycophenolate mofetil: A new therapeutic option in the treatment of blistering autoimmune diseases. J Am Acad Dermatol. 1999;40:957-60.
11. Powell AM, Albert S, Al Fares S, Harman KE, Setterfield J, Bhogal B, et al. An evaluation of the usefulness of mycophenolate mofetil in pemphigus. Br J Dermatol. 2003;149:138-45.
12. Grundmann-Kollman M, Kaskel P, Leiter U, Krahn G, Behrens S, Peter RU, et al. Treatment of pemphigus vulgaris and bullous pemphigoid with mycophenolate mofetil monotherapy. Arch Dermatol. 1999;135:724-5.
13. Megahed M, Schmiedeberg S, Becker J, Ruzicka T. Treatment of cicatricial pemphigoid with mycophenolate mofetil as a steroid-sparing agent. J Am Acad Dermatol. 2001;45:256-9.
14. Ingen-Housz-Oro S, Prost-Squarcioni C, Pascal F, Doan S, Brette MD, Bachelez H, et al. Pemphigoide cicatricielle: Traitement par mycophénolate mofétil. Ann Dermatol Venereol. 2005;132:13-16.
15. Schattenkirchner S, Eming S, Hunzelmann N, Krieg T, Smola H. Treatment of epidermolysis bullosa acquisita with mycophenolate mofetil and autologous keratinocyte grafting. Br J Dermatol. 1999;141:932-3.
16. Trebing D, Ziemer A. Acquired epidermolysis bullosa with a highly varied clinical picture and successful treatment with mycophenolate mofetil. Hautarzt. 2001;52:717-21.
17. Kowalzick L, Suckow S, Ziegler H, Waldmann T, Ponnighaus JM, Glaser V. Mycophenolate mofetil in epidermolysis bullosa acquisita. Dermatology. 2003;207:332-4.