Cotransplanted hepatic stellate cells enhance vascularization of islet allografts

Microsurgery

Volumn 27, Issue 4, 2007, Pages 324-327

  Yin, Zhenyu ^a   Wu, Wenhan ^a   Fung, John J ^a   Lu, Lina ^a   Qian, Shiguang ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIBODY; CD31 ANTIGEN; UNCLASSIFIED DRUG;

ALLOGRAFT; ANIMAL CELL; ANIMAL TISSUE; CELL SURVIVAL; CELL TRANSPLANTATION; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; MALE; MOUSE; NONHUMAN; PANCREAS TRANSPLANTATION; PRIORITY JOURNAL; REVASCULARIZATION; STELLATE CELL; TREATMENT OUTCOME; VASCULARIZATION;

ANIMALS; ANTIGENS, CD31; ENDOTHELIAL CELLS; GRAFT SURVIVAL; HEPATOCYTES; IMMUNOHISTOCHEMISTRY; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; TRANSPLANTATION, HOMOLOGOUS;

EID: 34250179886     PISSN: 07381085     EISSN: 10982752     Source Type: Journal    
DOI: 10.1002/micr.20365     Document Type: Conference Paper

References (19)

1. Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM, Rajotte RV. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000;343:230-238.
2. Kin T, Rajotte RV, Korbutt GS. Reassessment of the vascularization of renal subcapsular islet grafts. Pancreas 2004;29:59-63.
3. Menger MD, Yamauchi JI, Vollmar B. Revascularization and microcirculation of freshly grafted islets of Langerhans. World J Surg 2001;25:509-515.
4. Zhang N, Richter A, Suriawinata J, Harbaran S, Altomonte J, Cong L, Zhang H, Song K, Meseck M, Bromberg J, Dong H. Elevated vascular endothelial growth factor production in islets improves islet graft vascularization. Diabetes 2004;53:963-970.
5. Lammert E, Gu G, McLaughlin M, Brown D, Brekken R, Murtaugh LC, Gerber HP, Ferrara N, Melton DA. Role of VEGF-A in vascularization of pancreatic islets. Curr Biol 2003;13:1070-1074.
6. Reeves HL, Friedman SL. Activation of hepatic stellate cells - A key issue in liver fibrosis. Front Biosci 2002;7:808-826.
7. Vinas O, Bataller R, Sancho-Bru P, Gines P, Berenguer C, Enrich C, Ercilla G, Gallart T, Vives J, Arroyo V, Rodes J. Human hepatic stellate cells show features of antigen-presenting cells and stimulate lymphocyte proliferation. Hepatology 2003;38:919-929.
8. Kobayashi S, Seki S, Kawada N, Morikawa H, Nakatani K, Uyama N, Ikeda K, Nakajima Y, Arakawa T, Kaneda K. Apoptosis of T cells in the hepatic fibrotic tissue of the rat: A possible inducing role of hepatic myofibroblast-like cells. Cell Tissue Res 2003;311:353-364.
9. Yu MC, Chen CH, Liang X, Wang L, Gandhi CR, Fung JJ, Lu I, Qian S. Inhibition of T cell responses by hepatic stellate cells via B7-H1 mediated T cell apoptosis. Hepatology 2004;40:1312-1321.
10. Jansson L, Carlsson PO. Graft vascular function after transplantation of pancreatic islets. Diabetologia 2002;45:749-763.
11. Watanabe H, Sumi S, Urushihata T, Kitamura Y, Iwasaki S, Xu G, Yano S, Nio Y, Tamura K. Immunohistochemical studies on vascular endothelial growth factor and platelet endothelial cell adhesion molecule-1/CD-31 in islet transplantation. Pancreas 2000;21:165-173.
12. Narang AS, Cheng K, Henry J, Zhang C, Sabek O, Fraga D, Kotb M, Gaber AO, Mahato RI. Vascular endothelial growth factor gene delivery for revascularization in transplanted human islets. Pharm Res 2004;21:15-25.
13. Sambanis A. Encapsulated islets in diabetes treatment. Diabetes Technol Ther 2003;5:665-668.
14. Lee MK, Bae YH. Cell transplantation for endocrine disorders. Adv Drug Deliv Rev 2000;42:103-120.
15. De Vos P, Hamel AF, Tatarkiewicz K. Considerations for successful transplantation of encapsulated pancreatic islets. Diabetologia 2002; 45:159-173.
16. Zhang N, Richter A, Suriawinata J, Harbaran S, Altomonte J, Cong L, Zhang H, Meseck M, Bromberg J, Dong H. Elevated vascular endothelial growth factor production in islets improves islet graft vascularization. Diabetes 2004;53:963-970.
17. Friedman SL. Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications. Nat Clin Pract Gastroenterol Hepatol 2004;1:98-105.
18. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983;219: 983-985.
19. Rao P, Cozar-Castellano I, Roccisana J, Vasavada RC, Garcia-Ocana A. Hepatocyte growth factor gene therapy for islet transplantation. Expert Opin Biol Ther 2004;4:507-518.