Expression of estrogen receptor α and progesterone receptor in normal human breast epithelium

In Vivo

Volumn 21, Issue 3, 2007, Pages 535-540

  Umekita, Yoshihisa ^a   Souda, Masakazu ^a   Ohi, Yasuyo ^b   Rai, Yoshiaki ^b   Sagara, Yoshiaki ^b   Sagara, Yoshiatsu ^b   Yoshida, Hiroki ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b SAGARA HOSPITAL   (Japan)

Author keywords

Breast cancer; Estrogen receptor; Immunohistochemistry

Indexed keywords

ESTROGEN RECEPTOR ALPHA; PROGESTERONE RECEPTOR;

ADULT; AGED; ARTICLE; BREAST CARCINOMA; BREAST EPITHELIUM; CANCER PATIENT; CELL CONTACT; CONTROL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; POSTMENOPAUSE; PREMENOPAUSE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

EID: 34250178389     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Kelsey JL, Gammon MD and John EM: Reproductive and hormonal risk factors: reproductive factors and breast cancer. Epidemiol Rev 15: 36-47, 1993.
2. Williams G, Anderson E, Howell A, Watson R, Coyne J, Roberts SA and Potten CS: Oral contraceptive (OCP) use increases proliferation and decreases estrogen receptor content of epithelial cells in the normal human breast. Int J Cancer 48: 206-210, 1991.
3. Anderson TJ and Battersby S: The involvement of estrogen in the development and function of the normal breast: histological evidence. Proc R Soc Edinb 95B: 23-32, 1989.
4. Peterson OW, Hoyer PE and van Deurs B: Frequency and distribution of estrogen receptor-positive cells in normal, nonlactating human breast tissue. Cancer Res 47: 5748-5751, 1987.
5. Clarke RB, Howell A, Potten CS and Anderson E: Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res 57: 4987-4991, 1997.
6. King TA, Gemignani ML, Li W, Giri DD, Panageas KS, Bogomolniy, Arroyo C, Olvera N, Robson ME, Offit K, Borgen PI and Boyd J: Increased progesterone receptor expression in benign epithelium of BRCA-related breast cancers. Cancer Res 64: 5051-5053, 2004.
7. Gobbi H, Dupont WD, Parl FF, Schuyler PA, Plummer WD, Olson SJ and Page DL: Breast cancer risk associated with estrogen receptor expression in epithelial hyperplasia lacking atypia and adjacent lobular units. Int J Cancer 113: 857-859, 2005.
8. Tavassoli FA and Devilee P (eds.): World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. Lyon, IARC Press, p. 11, 2003.
9. Umemura S, Kurosumi M, Moriya T, Oyama T, Arihiro K, Yamashita H, Umekita Y, Komoike Y, Shmizu C, Fukushima H, Kajiwara H and Akiyama F: Immunohistochemical evaluation for hormone receptors in breast cancer: A practically useful evaluation system and handling protocol. Breast Cancer 13: 232-235, 2006.
10. Shoker BS, Jarvis C, Sibson DR, Walker C and Sloane JP: Oestrogen receptor expression in the normal and pre-cancerous breast. J Pathol 188: 237-244, 1999.
11. Shoker BS, Jarvis C, Clarke RB, Anderson E, Hewlett J, Davies MPA, Sibson DR and Sloane JP: Estrogen reeeptor-positive proliferating cells in the normal and precaneerous breast. Am J Pathol 155: 1811-1815, 1999.
12. Khan SA, Yee KA, Kaplan C and Siddiqui F: Estrogen receptor α expression in normal human breast epithelium is consistent over time. Int J Cancer 102: 334-337, 2002.
13. Ricketts D, Turnbull L, Ryall G, Bakhshi R, Rawson NSB, Gazet J-C, Nolan C and Coombes RC: Estrogen and progesterone receptors in the normal female breast. Cancer Res 51: 1817-1822, 1991.
14. Khan SA, Rogers MAM, Obando JA and Tamsen A: Estrogen receptor expression of benign breast epithelium and its association with breast cancer. Cancer Res 54: 993-997, 1994.
15. Lawson JS, Field AS, Champion S, Tran D, Ishikura H and Trichopoulos D: Low oestrogen receptor α expression in normal breast tissue underlies low breast cancer incidence in Japan. Lancet 354: 1787-1788, 1999.