Effects of Hibiscus rosa sinensis L (Malvaceae) on wound healing activity: A preclinical study in a Sprague Dawley rat

International Journal of Lower Extremity Wounds

Volumn 6, Issue 2, 2007, Pages 76-81

  Shivananda Nayak, B ^a   Sivachandra Raju, S ^a   Orette, F A ^a   Chalapathi Rao, A V ^a  

^a UNIVERSITY OF THE WEST INDIES   (Trinidad and Tobago)

Author keywords

Dead space wound; Excision wound; Hibiscus rosa sinensis; Hydroxyproline; Incision wound

Indexed keywords

HIBISCUS ROSA SINENSIS EXTRACT; HYDROXYPROLINE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BETA HEMOLYTIC STREPTOCOCCUS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; EPITHELIZATION; ESCHERICHIA COLI; FLOWER; GRANULATION TISSUE; HIBISCUS; INCISION; NONHUMAN; PANTOEA AGGLOMERANS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RAT; STAPHYLOCOCCUS AUREUS; TENSILE STRENGTH; WOUND; WOUND CONTRACTION; WOUND HEALING; WOUND INFECTION;

ANIMALS; ANTI-INFECTIVE AGENTS; COLLAGEN; FLOWERS; GRANULATION TISSUE; HIBISCUS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SOFT TISSUE INJURIES; WOUND HEALING;

EID: 34250174545     PISSN: 15347346     EISSN: 15526941     Source Type: Journal    
DOI: 10.1177/1534734607302840     Document Type: Article

References (20)

1. Stadelmann WK, Digenis AG, Tobin GR Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg 1998 ; 176 (2) 26S - 38S.
2. Iba Y., Shibata A., Kato M., Masukawa T. Possible involvement of mast cells in collagen remodeling in the late phase of cutaneous wound healing in mice. Int Immunopharmacol 2004 ; 4 (14). 1873-80.
3. Midwood KS, Williams LV, Schwarzbauer JE Tissue repair and the dynamics of the extracellular matrix. Int J Biochem Cell Biol 2004 ; 36 (6). 1031-7.
4. Garg HG Scar-less wound healing. New York: Marcel Dekker. Electronic book; 2000.
5. Gauthaman KK, Saleem MT, Thanislas PT, Prabhu VV, Krishnamoorthy KK, Devaraj NS, et al. Cardioprotective effect of the Hibiscus rosa sinensis flowers in an oxidative stress model of myocardial ischemic reperfusion injury in rat. BMC Complement Altern Med 2006 ; 6: 32.
6. Reddy CM, Murthy DR, Patil SB Antispermatogenic and androgenic activities of various extracts of Hibiscus rosa sinensis in albino mice. Indian J Exp Biol 1997 ; 35 (11). 1170-4.
7. Kasture VS, Chopde CT, Deshmukh VK Anticonvulsive activity of Albizzia lebbeck, Hibiscus rosa sinensis and Butea monosperma in experimental animals. J Ethnopharmacol 2000 ; 71 (1-2). 65-75.
8. Sachdewa A., Khemani LD Effect of Hibiscus rosa sinensis Linn. Ethanol flower extract on blood glucose and lipid profile in streptozotocin-induced diabetes in rats. J Ethnopharmacol 2003 ; 89 (1). 61-6.
9. Jalalpure SS, Patil MB, Prakash NS, Hemalatha K., Manvi FV Hepatoprotective activity of fruits of Piper longum L. Indian J Pharm Sci 2003 ; 65: 363-6.
10. Morton JJ, Malone MH Evaluation of vulnerary activity by an open wound procedure in rats. Arch Int Pharmacodyn Ther 1972 ; 196: 117-26.
11. Diwan PV, Tilloo LD, Kulkarni DR Influence of Tridax procumbens on wound healing. Indian J Med Res 1982 ; 75: 460-4. 12. Ehrlich HP, Hunt TK Effect of cortisone and vitamin A on wound healing. Ann Surg 1968 ; 167: 324-8.
12. Lee KH Studies on the mechanism of action of salicylate II. Retardation of wound healing by aspirin. J Pharm Sci 1968 ; 57: 1042-3.
13. Turner RA Screening methods in pharmacology. New York: Academic Press ; 1965.
14. Neuman RE, Logan MA The determination of hydroxyproline. J Biol Chem 1950 ; 184 (1). 299-306.
15. Kumar R., Katoch SS, Sharma S. β-Adrenoceptor agonist treatment reverses denervation atrophy with augmentation of collagen proliferation in denervated mice gastrocnemius muscle. Indian J Exp Biol 2006 ; 44 (5). 371-6.
16. Juranek I., Bezek S. Controversy of free radical hypothesis: reactive oxygen species-cause or consequence of tissue injury? Gen Physiol Biophys 2005 ; 24 (3). 263-78.
17. Henriques A., Jackson S., Cooper R., Burton N. Free radical production and quenching in honeys with wound healing potential. J Antimicrob Chemother 2006 ; 58 (4). 773-7.
18. Gilliver SC, Ashworth JJ, Mills SJ, Hardman MJ, Ashcroft GS Androgens modulate the inflammatory response during acute wound healing. J Cell Sci 2006 ; 119: 722-32.
19. Adhirajan N., Ravi Kumar T, Shanmugasundaram N., Babu M. In vivo and in vitro evaluation of hair growth potential of Hibiscus rosa-sinensis Linn. J Ethnopharmacol 2003 ; 88 (2-3). 235-9.
20. Habibipour S., Oswald TM, Zhang F., Joshi P., Zhou XC, Dorsett-Martin W., Lineaweaver WC Effect of sodium diphenylhydantoin on skin wound healing in rats. Plast Reconstr Surg 2003 ; 112 (6). 1620-7.