Opposing actions of TGFβ1 and FGF2 on growth, differentiation and extracellular matrix accumulation in prostatic stromal cells

Growth Factors

Volumn 24, Issue 4, 2006, Pages 233-241

  Cross, Neil A ^a   Reid, Sheilagh R ^a   Harvey, Amanda J ^b   Jokonya, Nickie ^a   Eaton, Colby L ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; IGFBP3 PROTEIN, HUMAN; SOMATOMEDIN BINDING PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BIOAVAILABILITY; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE EXACERBATION; EXTRACELLULAR MATRIX; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROSTATE HYPERTROPHY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN SYNTHESIS REGULATION; REAL TIME POLYMERASE CHAIN REACTION; STROMA CELL; WESTERN BLOTTING; BIOLOGICAL MODEL; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; HUMAN; MALE; METABOLISM; MOLECULAR GENETICS; PROSTATE;

CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR MATRIX; FIBROBLAST GROWTH FACTOR 2; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; MALE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PROSTATE; PROSTATIC HYPERPLASIA; STROMAL CELLS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 34250014236     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.1080/08977190600976501     Document Type: Article

References (32)

1. Bostwick, DG, Cooner, WH, Denis, L., Jones, GW, Scardino, PT and Murphy, GP (1992) The association of benign prostatic hyperplasia and cancer of the prostate. Cancer, 70:1, pp. 291-301.
2. Bretland, AJ and Reid, SV (2001) Role of endogenous transforming growth factor beta (TGF beta) I in prostatic stromal cells. Prostate, 48, pp. 297-304.
3. Cardoso, LE and Falcao, PG (2004) Increased and localized accumulation of chondroitin sulphate proteoglycans in the hyperplastic human prostate. BJU Int, 93, pp. 532-538.
4. Cohen, P. and Nunn, SE (2000) Transforming growth factor-beta induces growth inhibition and IGF-binding protein-3 production in prostatic stromal cells: Abnormalities in cells cultured from benign prostatic hyperplasia tissues. J Endocrinol., 164, pp. 215-223.
5. Cross, NA and Chandrasekharan, S. (2005) The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: Relevance to the accumulation of versican. Prostate, 63, pp. 269-275.
6. Dallas, SL, Zhao, S., Cramer, SD, Chen, Z., Peehl, DM and Bonewald, LF (2005) Preferential production of latent transforming growth factor beta-2 by primary prostatic epithelial cells and its activation by prostate-specific antigen. J Cell Physiol, 202, pp. 361-370.
7. Flanders, KC, Holder, MG and Winokur, TS (1995) Autoinduction of mRNA and protein expression for transforming growth factor-betas in cultured cardiac cells. J Mol Cell Cardiol, 27, pp. 805-812.
8. Fukabori, Y., Nakano, K., Ohyama, A. and Yamanaka, H. (1997) Stimulative effect of transforming growth factor-beta on collagen synthesis by human prostatic stromal cells in vitro. Int J Urol, 4, pp. 597-602.
9. Glassman, DT and Chon, JK (2001) Combined effect of terazosin and finasteride on apoptosis, cell proliferation,and transforming growth factor-beta expression in benign prostatic hyperplasia. Prostate, 46, pp. 45-51.
10. Hong, JH and Song, C. (2004) Estrogen induction of smooth muscle differentiation of human prostatic stromal cells is mediated by transforming growth factor-beta. J Urol, 171, pp. 1965-1969.
11. Ichiki, Y., Smith, EA, LeRoy, EC and Trojanowska, M. (1997) Basic fibroblast growth factor inhibits basal and transforming growth factor-beta induced collagen alpha 2(I) gene expression in scleroderma and normal fibroblasts. J Rheumatol, 24, pp. 90-95.
12. Klingler, HC and Bretland, AJ (1999) Regulation of prostatic stromal cell growth and function by transforming growth factor beta (TGF beta). Prostate, 41, pp. 110-120.
13. Kyprianou, N. and Isaacs, JT (1988) Identification of a cellular receptor for transforming growth factor-beta in rat ventral prostate and its negative regulation by androgens. Endocrinology, 123, pp. 2124-2139.
14. Kyprianou, N. and Isaacs, JT (1989) Expression of transforming growth factor-beta in the rat ventral prostate during castration-induced programmed cell-death. Mol Endocrinol, 3, pp. 1515-1522.
15. Kyprianou, N. and Jacobs, SC (1996) Apoptotic versus proliferative activities in human benign prostatic hyperplasia. Hum Pathol, 27, pp. 668-675.
16. Locklin, RM, Oreffo, RO and Triffitt, JT (1999) Effects of TGFbeta and bFGF on the differentiation of human bone marrow stromal fibroblasts. Cell Biol Int, 23, pp. 185-194.
17. Luo, J. and Dunn, T. (2002) Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis. Prostate, 51, pp. 189-200.
18. Mori, H. and Maki, M. (1990) Increased expression of genes for basic fibroblast growth-factor and transforming growth-factor type-beta-2 in human benign prostatic hyperplasia. Prostate, 16, pp. 71-80.
19. Neptune, ER and Frischmeyer, PA (2003) Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome. Nat Genet, 33, pp. 407-411.
20. Niu, Y. (2001) Proliferation and differentiation of prostatic stromal cells. BJU Int, 87, pp. 386-393.
21. Peehl, DM and Cohen, P. (1996) The role of insulin-like growth factors in prostate biology. J Androl, 17, pp. 2-4.
22. Peehl, DM and Sellers, RG (1997) Induction of smooth muscle cell phenotype in cultured human prostatic stromal cells. Exp Cell Res, 232, pp. 208-215.
23. Phillips, AO, Topley, N., Morrisey, K., Williams, JD and Steadman, R. (1997) Basic fibroblast growth factor stimulates the release of preformed transforming growth factor beta 1 from human proximal tubular cells in the absence of de novo gene transcription or mRNA translation. Lab Invest, 76, pp. 591-600.
24. Royuela, M., De Miguel, MP, Bethencourt, FR, Sanchez-Chapado, M., Fraile, B. and Paniagua, R. (1998) Transforming growth factor beta 1 and its receptor types I and II. Comparison in human normal prostate, benign prostatic hyperplasia, and prostatic carcinoma. Growth Factors, 16, pp. 101-110.
25. Sakko, AJ and Ricciardelli, C. (2001) Versican accumulation in human prostatic fibroblast cultures is enhanced by prostate cancer cell-derived transforming growth factor beta1. Cancer Res, 61, pp. 926-930.
26. Salm, SN and Koikawa, Y. (2000) Generation of active TGF-beta by prostatic cell cocultures using novel basal and luminal prostatic epithelial cell lines. J Cell Physiol, 184, pp. 70-79.
27. Sato, M., Muragaki, Y., Saika, S., Roberts, AB and Ooshima, A. (2003) Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest, 112, pp. 1486-1494.
28. Shapiro, E. and Becich, MJ (1992) The relative proportion of stromal and epithelial hyperplasia is related to the development of symptomatic benign prostate hyperplasia. J Urol, 147, pp. 1293-1297.
29. Story, MT and Hopp, KA (1996) Expression of transforming growth factor beta 1 (TGF beta(1))-beta(2), and -beta(3) by cultured human prostate cells. J Cell Physiol, 169, pp. 97-107.
30. Timme, TL, Truong, LD, Slawin, KM, Kadmon, D., Park, SH and Thompson, TC (1995) Mesenchymal-epithelial interactions and transforming growth factor-beta 1 expression during normal and abnormal prostatic growth. Microsc Res Tech, 30, pp. 333-341.
31. Timme, TL and Yang, G. (1996) Retroviral transduction of transforming growth factor-beta1 induces pleiotropic benign prostatic growth abnormalities in mouse prostate reconstitutions. Lab Invest, 74, pp. 747-760.
32. Untergasser, G. and Gandera, R. (2005) Profiling molecular targets of TGF-b1 in prostate fibroblast-to-myofibroblast transdifferentiation. Mech Ageing Dev, 126, pp. 59-69.