Dihydrotestosterone inhibits tumor necrosis factor α induced interleukin-1α mRNA expression in rheumatoid fibroblast-like synovial cells

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 6, 2007, Pages 1140-1143

  Itoh, Yuka ^a   Hayashi, Hidetoshi ^a   Xu, Jian ^a   Takii, Takemasa ^a   Miyazawa, Keiji ^b   Ariga, Hiroyoshi ^c   Akahoshi, Tohru ^d   Waguri Nagaya, Yuko ^e   Otsuka, Takanobu ^e   Okamoto, Takashi ^e   Onozaki, Kikuo ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b KISSEI PHARMACEUTICAL CO LTD   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Androgen; Androgen receptor; Interleukin 1 (IL 1); Rheumatoid arthritis; Synoviocytes; Tumor necrosis factor (TNF)

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; HORMONE RECEPTOR BLOCKING AGENT; HYDROXYFLUTAMIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; RHEUMATOID ARTHRITIS; SEX DIFFERENCE; SYNOVIOCYTE;

ARTHRITIS, RHEUMATOID; CELL CULTURE TECHNIQUES; CELL LINE, TRANSFORMED; CELLS, CULTURED; DIHYDROTESTOSTERONE; FLUTAMIDE; GENES, REPORTER; HUMANS; INTERLEUKIN-1ALPHA; LUCIFERASES; RECEPTORS, ANDROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYNOVIAL MEMBRANE; TIME FACTORS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34249993853     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.1140     Document Type: Article

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