메뉴 건너뛰기




Volumn 19, Issue 4, 2007, Pages 401-406

Health-related quality-of-life assessment in gastrointestinal cancer: Are results relevant for clinical practice?

Author keywords

Colorectal cancer; Esophageal cancer; Gastric cancer; Pancreatic cancer; Quality of life

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DOCETAXEL; EPIRUBICIN; FLOXURIDINE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IRINOTECAN; OXALIPLATIN; RALTITREXED; URACIL;

EID: 34249993099     PISSN: 10408746     EISSN: None     Source Type: Journal    
DOI: 10.1097/CCO.0b013e32816f7704     Document Type: Review
Times cited : (8)

References (41)
  • 1
    • 33747188339 scopus 로고    scopus 로고
    • Darling G, Eton DT, Sulman J, et al. Validation of the Functional Assessment of Cancer Therapy esophageal cancer subscale. Cancer 2006; 107:854-863. This is a new valid questionnaire to mesure QoL in esophageal cancer patients, to be used with the FACT-G.
    • Darling G, Eton DT, Sulman J, et al. Validation of the Functional Assessment of Cancer Therapy esophageal cancer subscale. Cancer 2006; 107:854-863. This is a new valid questionnaire to mesure QoL in esophageal cancer patients, to be used with the FACT-G.
  • 2
    • 17744366158 scopus 로고    scopus 로고
    • A prospective comparison of quality of life measures for patients with esophageal cancer
    • Blazeby JM, Kavadas V, Vickery CW, et al. A prospective comparison of quality of life measures for patients with esophageal cancer. Qual Life Res 2005; 14:387-393.
    • (2005) Qual Life Res , vol.14 , pp. 387-393
    • Blazeby, J.M.1    Kavadas, V.2    Vickery, C.W.3
  • 3
    • 27744437309 scopus 로고    scopus 로고
    • Influence of surgery-related factors on quality of life after esophageal or cardia cancer resection
    • Viklund P, Lindblad M, Lagergren J. Influence of surgery-related factors on quality of life after esophageal or cardia cancer resection. World J Surg 2005; 29:841-848.
    • (2005) World J Surg , vol.29 , pp. 841-848
    • Viklund, P.1    Lindblad, M.2    Lagergren, J.3
  • 4
    • 33745179241 scopus 로고    scopus 로고
    • Viklund P, Wengström Y, Rouvelas I, et al. Quality of life and persisting symptoms after oesophageal cancer surgery. Eur J Cancer 2006; 42:1407-1414. This study demonstrates probably for the first time persistence of severe esophageal symptoms after esophageal surgery and also the usefulness of the EORTC specific module, the OES-18.
    • Viklund P, Wengström Y, Rouvelas I, et al. Quality of life and persisting symptoms after oesophageal cancer surgery. Eur J Cancer 2006; 42:1407-1414. This study demonstrates probably for the first time persistence of severe esophageal symptoms after esophageal surgery and also the usefulness of the EORTC specific module, the OES-18.
  • 5
    • 33646594743 scopus 로고    scopus 로고
    • Satisfaction with care: An independent outcome measure in surgical oncology
    • Poor QoL after surgery may be compatible with high satisfaction with care, demonstrating that these two patients' outcomes are not correlated
    • Avery KNL, Metcalfe C, Nicklin J, et al. Satisfaction with care: an independent outcome measure in surgical oncology. Ann Surg Oncol 2006; 13:817-822. Poor QoL after surgery may be compatible with high satisfaction with care, demonstrating that these two patients' outcomes are not correlated.
    • (2006) Ann Surg Oncol , vol.13 , pp. 817-822
    • Avery, K.N.L.1    Metcalfe, C.2    Nicklin, J.3
  • 6
    • 32944467792 scopus 로고    scopus 로고
    • Minimally invasive esophagectomy: Short- and long-term outcomes
    • Surprisingly, laparoscopic and thoracoscopic procedures for esophagectomy seriously reduces QoL, apparently not differently from transthoracic surgery according to the results of this series
    • Leibman S, Smithers BM, Gotley DC, et al. Minimally invasive esophagectomy: short- and long-term outcomes. Surg Endosc 2006; 20:428-433. Surprisingly, laparoscopic and thoracoscopic procedures for esophagectomy seriously reduces QoL, apparently not differently from transthoracic surgery according to the results of this series.
    • (2006) Surg Endosc , vol.20 , pp. 428-433
    • Leibman, S.1    Smithers, B.M.2    Gotley, D.C.3
  • 7
    • 17644377901 scopus 로고    scopus 로고
    • Health-related quality of life during neoadjuvant treatment and surgery for localized esophageal carcinoma
    • Blazeby JM, Sanford E, Falk SJ, et al. Health-related quality of life during neoadjuvant treatment and surgery for localized esophageal carcinoma. Cancer 2005; 103:1791-1799.
    • (2005) Cancer , vol.103 , pp. 1791-1799
    • Blazeby, J.M.1    Sanford, E.2    Falk, S.J.3
  • 8
    • 33748416886 scopus 로고    scopus 로고
    • Prospective evaluation of quality of life in patients with localized oesophageal cancer treated by multimodality therapy or surgery alone
    • Reynolds JV, McLaughlin R, Moore J, et al. Prospective evaluation of quality of life in patients with localized oesophageal cancer treated by multimodality therapy or surgery alone. Br J Surg 2006; 93:1084-1090.
    • (2006) Br J Surg , vol.93 , pp. 1084-1090
    • Reynolds, J.V.1    McLaughlin, R.2    Moore, J.3
  • 9
    • 33646183368 scopus 로고    scopus 로고
    • Bonnetain F, Bouché O, Michel P, et al. A comparative longitudinal quality of life study using the Spitzer quality of life index in a randomized multicenter phase III trial (FFCD 9102): chemoradiation followed by surgery compared with chemoradiation alone in locally advanced squamous resectable thoracic esophageal cancer. Ann Oncol 2006; 17:827-834. The authors present the first study investigating longitudinal QoL during a randomized study with chemoradiation.
    • Bonnetain F, Bouché O, Michel P, et al. A comparative longitudinal quality of life study using the Spitzer quality of life index in a randomized multicenter phase III trial (FFCD 9102): chemoradiation followed by surgery compared with chemoradiation alone in locally advanced squamous resectable thoracic esophageal cancer. Ann Oncol 2006; 17:827-834. The authors present the first study investigating longitudinal QoL during a randomized study with chemoradiation.
  • 10
    • 14944381126 scopus 로고    scopus 로고
    • A pragmatic randomised controlled trial of the cost-effectiveness of palliative therapies for patients with inoperable oesophageal cancer
    • Shenfine J, McNamee P, Steen N, et al. A pragmatic randomised controlled trial of the cost-effectiveness of palliative therapies for patients with inoperable oesophageal cancer. Health Technol Assess 2005; 9:1-121.
    • (2005) Health Technol Assess , vol.9 , pp. 1-121
    • Shenfine, J.1    McNamee, P.2    Steen, N.3
  • 11
    • 33745534430 scopus 로고    scopus 로고
    • The neo-adjuvant, surgical and adjuvant treatment of gastric adenocarcinoma. Current expert opinion derived from the Seventh World Congress on Gastrointestinal Cancer, Barcelona, 2005
    • Suppl 6:vi13-vi18
    • Van Cutsem E, Dicato M, Arber N, et al. The neo-adjuvant, surgical and adjuvant treatment of gastric adenocarcinoma. Current expert opinion derived from the Seventh World Congress on Gastrointestinal Cancer, Barcelona, 2005. Ann Oncol 2006; 17 (Suppl 6):vi13-vi18.
    • (2006) Ann Oncol , pp. 17
    • Van Cutsem, E.1    Dicato, M.2    Arber, N.3
  • 12
    • 33751395442 scopus 로고    scopus 로고
    • Health-related quality of life among disease-free stomach cancer survivors in Korea
    • This large study in survivors suggests that QoL is similar in patients who underwent total or subtotal gastrectomy
    • Bae JM, Kim S, Kim YW, et al. Health-related quality of life among disease-free stomach cancer survivors in Korea. Qual Life Res 2006; 15:1587-1596. This large study in survivors suggests that QoL is similar in patients who underwent total or subtotal gastrectomy.
    • (2006) Qual Life Res , vol.15 , pp. 1587-1596
    • Bae, J.M.1    Kim, S.2    Kim, Y.W.3
  • 13
    • 30044446936 scopus 로고    scopus 로고
    • Longitudinal quality of life study in patients with metastatic gastric cancer. Analysis modalities and clinical applicability of QoL in randomized phase II trial in a digestive oncology
    • Bonnetain F, Bouché O, Conroy T, et al. Longitudinal quality of life study in patients with metastatic gastric cancer. Analysis modalities and clinical applicability of QoL in randomized phase II trial in a digestive oncology. Gastroenterol Clin Biol 2005; 29:1113-1124.
    • (2005) Gastroenterol Clin Biol , vol.29 , pp. 1113-1124
    • Bonnetain, F.1    Bouché, O.2    Conroy, T.3
  • 14
    • 33750949065 scopus 로고    scopus 로고
    • Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: A report of the V325 Study Group
    • Van Cutsem E, Moiseyenko VM, Tjulandin S, et al. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study Group. J Clin Oncol 2006; 24:4991-4997.
    • (2006) J Clin Oncol , vol.24 , pp. 4991-4997
    • Van Cutsem, E.1    Moiseyenko, V.M.2    Tjulandin, S.3
  • 15
    • 18844446924 scopus 로고    scopus 로고
    • Randomized clinical trial of pylorus-preserving duodenopancreatectomy versus classical Whipple resection-long term results
    • Seiler CA, Wagner M, Bachmann T, et al. Randomized clinical trial of pylorus-preserving duodenopancreatectomy versus classical Whipple resection-long term results. Br J Surg 2005; 92:547-556.
    • (2005) Br J Surg , vol.92 , pp. 547-556
    • Seiler, C.A.1    Wagner, M.2    Bachmann, T.3
  • 16
    • 33749590358 scopus 로고    scopus 로고
    • Symptom profiles and palliative care in advanced pancreatic cancer - a prospective study
    • Labori KJ, Hjermstad MJ, Wester T, et al. Symptom profiles and palliative care in advanced pancreatic cancer - a prospective study. Support Care Cancer 2006; 14:1126-1133.
    • (2006) Support Care Cancer , vol.14 , pp. 1126-1133
    • Labori, K.J.1    Hjermstad, M.J.2    Wester, T.3
  • 17
    • 27544500200 scopus 로고    scopus 로고
    • A prospective randomized trial comparing standard pancreatoduodenectomy with pancreatoduodenectomy with extended lymphadenectomy in resectable pancreatic head adenocarcinoma
    • discussion 628-630
    • Farnell MB, Pearson RK, Sarr MG, et al. A prospective randomized trial comparing standard pancreatoduodenectomy with pancreatoduodenectomy with extended lymphadenectomy in resectable pancreatic head adenocarcinoma. Surgery 2005; 138:618-628; discussion 628-630.
    • (2005) Surgery , vol.138 , pp. 618-628
    • Farnell, M.B.1    Pearson, R.K.2    Sarr, M.G.3
  • 18
    • 17144380803 scopus 로고    scopus 로고
    • Quality of life after curative or palliative surgical treatment of pancreatic and periampullary carcinoma
    • Nieveen van Dijkum EJM, Kuhlmann KFD, Terwee CB, et al. Quality of life after curative or palliative surgical treatment of pancreatic and periampullary carcinoma. Br J Surg 2005; 92:471-477.
    • (2005) Br J Surg , vol.92 , pp. 471-477
    • Nieveen van Dijkum, E.J.M.1    Kuhlmann, K.F.D.2    Terwee, C.B.3
  • 19
    • 27644450514 scopus 로고    scopus 로고
    • Quality-of-life after total pancreatectomy: Is it really that bad on long-term follow-up?
    • discussion 1066-1067
    • Billings BJ, Christein JD, Harmsen WS, et al. Quality-of-life after total pancreatectomy: is it really that bad on long-term follow-up? J Gastrointest Surg 2005; 9:1059-1066; discussion 1066-1067.
    • (2005) J Gastrointest Surg , vol.9 , pp. 1059-1066
    • Billings, B.J.1    Christein, J.D.2    Harmsen, W.S.3
  • 20
    • 20044374358 scopus 로고    scopus 로고
    • Irinotecan plus oxaliplatin and leucovorin-modulated fluorouracil in advanced pancreatic cancer: A Groupe Tumeurs Digestives of the Fédération Nationale des Centres de Lutte Contre le Cancer study
    • Conroy T, Paillot B, Francois E, et al. Irinotecan plus oxaliplatin and leucovorin-modulated fluorouracil in advanced pancreatic cancer: a Groupe Tumeurs Digestives of the Fédération Nationale des Centres de Lutte Contre le Cancer study. J Clin Oncol 2005; 23:1228-1236.
    • (2005) J Clin Oncol , vol.23 , pp. 1228-1236
    • Conroy, T.1    Paillot, B.2    Francois, E.3
  • 21
    • 33645277368 scopus 로고    scopus 로고
    • Raltitrexed-eloxatin salvage chemotherapy in gemcitabine-resistant metastatic pancreatic cancer
    • Reni M, Pasetto L, Aprile G, et al. Raltitrexed-eloxatin salvage chemotherapy in gemcitabine-resistant metastatic pancreatic cancer. Br J Cancer 2006; 94:785-791.
    • (2006) Br J Cancer , vol.94 , pp. 785-791
    • Reni, M.1    Pasetto, L.2    Aprile, G.3
  • 22
    • 33750293070 scopus 로고    scopus 로고
    • Quality of life assessment in advanced pancreatic adenocarcinoma: Results from a phase III randomized trial
    • This is another demonstration that achievement of an objective tumor response in advanced pancreatic cancer is associated with improved QoL
    • Reni M, Bonetto E, Cordio S, et al. Quality of life assessment in advanced pancreatic adenocarcinoma: results from a phase III randomized trial. Pancreatology 2006; 6:454-463. This is another demonstration that achievement of an objective tumor response in advanced pancreatic cancer is associated with improved QoL.
    • (2006) Pancreatology , vol.6 , pp. 454-463
    • Reni, M.1    Bonetto, E.2    Cordio, S.3
  • 23
    • 33748363292 scopus 로고    scopus 로고
    • Surgery or endoscopy for palliation of biliary obstruction due to metastatic pancreatic cancer
    • Artifon ELA, Sakai P, Cunha JEM, et al. Surgery or endoscopy for palliation of biliary obstruction due to metastatic pancreatic cancer. Am J Gastroenterol 2006; 101:2031-2037.
    • (2006) Am J Gastroenterol , vol.101 , pp. 2031-2037
    • Artifon, E.L.A.1    Sakai, P.2    Cunha, J.E.M.3
  • 24
    • 19944380109 scopus 로고    scopus 로고
    • Phase III study of 5FU, etoposide and leucovorin (FELV) compared to epirubicin, cisplatin and 5FU(ECF) in previously untreated patients with advanced biliary cancer
    • Rao S, Cunningham D, Hawkins RE, et al. Phase III study of 5FU, etoposide and leucovorin (FELV) compared to epirubicin, cisplatin and 5FU(ECF) in previously untreated patients with advanced biliary cancer. Br J Cancer 2005; 92:1650-1654.
    • (2005) Br J Cancer , vol.92 , pp. 1650-1654
    • Rao, S.1    Cunningham, D.2    Hawkins, R.E.3
  • 25
    • 7044238395 scopus 로고    scopus 로고
    • Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18
    • Blazeby JM, Currie E, Zee BC, et al. Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18. Eur J Cancer 2004; 40:2439-2444.
    • (2004) Eur J Cancer , vol.40 , pp. 2439-2444
    • Blazeby, J.M.1    Currie, E.2    Zee, B.C.3
  • 26
    • 18844388715 scopus 로고    scopus 로고
    • Proxy ratings of health related quality of life in patients with hepatocellular carcinoma
    • Steel JL, Geller DA, Carr BI. Proxy ratings of health related quality of life in patients with hepatocellular carcinoma. Qual Life Res 2005; 14:1025-1033.
    • (2005) Qual Life Res , vol.14 , pp. 1025-1033
    • Steel, J.L.1    Geller, D.A.2    Carr, B.I.3
  • 27
    • 33745591930 scopus 로고    scopus 로고
    • Quality of life is predictive of survival in patients with unresectable hepatocellular carcinoma
    • This excellent paper demonstates that QoL is an independent prognostic factor for survival in advanced hepatocarcinoma. QoL parameters should be used as stratification factors in clinical trials
    • Yeo W, Mo FKF, Koh J, et al. Quality of life is predictive of survival in patients with unresectable hepatocellular carcinoma. Ann Oncol 2006; 17:1083-1089. This excellent paper demonstates that QoL is an independent prognostic factor for survival in advanced hepatocarcinoma. QoL parameters should be used as stratification factors in clinical trials.
    • (2006) Ann Oncol , vol.17 , pp. 1083-1089
    • Yeo, W.1    Mo, F.K.F.2    Koh, J.3
  • 28
    • 33644982630 scopus 로고    scopus 로고
    • Role of radiotherapy with surgery for T3 and resectable T4 rectal cancer: Evidence from randomized trials
    • Ortholan C, Francois E, Thomas O, et al. Role of radiotherapy with surgery for T3 and resectable T4 rectal cancer: evidence from randomized trials. Dis Colon Rectum 2006; 49:302-310.
    • (2006) Dis Colon Rectum , vol.49 , pp. 302-310
    • Ortholan, C.1    Francois, E.2    Thomas, O.3
  • 29
    • 18944386288 scopus 로고    scopus 로고
    • Colonic J-pouch anal anastomosis after ultralow anterior resection with upper sphincter excision for low-lying rectal cancer
    • Park JG, Lee MR, Lim SB, et al. Colonic J-pouch anal anastomosis after ultralow anterior resection with upper sphincter excision for low-lying rectal cancer. World J Gastroenterol 2005; 11:2570-2573.
    • (2005) World J Gastroenterol , vol.11 , pp. 2570-2573
    • Park, J.G.1    Lee, M.R.2    Lim, S.B.3
  • 30
    • 34250015248 scopus 로고    scopus 로고
    • Functional results and quality of life for patients with very low rectal cancer undergoing coloanal anastomosis or perineal colostomy with colonic muscular graft
    • Nov 21; [Epub ahead of print, The authors present similar QoL results for patients with very low rectal cancer undergoing two reconstruction techniques after APR
    • Pocard M, Sideris L, Zenasni F, et al. Functional results and quality of life for patients with very low rectal cancer undergoing coloanal anastomosis or perineal colostomy with colonic muscular graft. Eur J Surg Oncol 2006 Nov 21; [Epub ahead of print]. The authors present similar QoL results for patients with very low rectal cancer undergoing two reconstruction techniques after APR.
    • (2006) Eur J Surg Oncol
    • Pocard, M.1    Sideris, L.2    Zenasni, F.3
  • 31
    • 23944476380 scopus 로고    scopus 로고
    • Quality of life and functional outcome following anterior or abdominoperineal resection for rectal cancer
    • Guren MG, Eriksen MT, Wiig JN, et al. Quality of life and functional outcome following anterior or abdominoperineal resection for rectal cancer. Eur J Surg Oncol 2005; 31:735-742.
    • (2005) Eur J Surg Oncol , vol.31 , pp. 735-742
    • Guren, M.G.1    Eriksen, M.T.2    Wiig, J.N.3
  • 32
    • 14844288079 scopus 로고    scopus 로고
    • Assessment of quality of life in patients with rectal cancer treated by preoperative radiotherapy: A longitudinal prospective study
    • Allal AS, Gervaz P, Gertsch P, et al. Assessment of quality of life in patients with rectal cancer treated by preoperative radiotherapy: a longitudinal prospective study. Int J Radiat Oncol Biol Phys 2005; 61:1129-1135.
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , pp. 1129-1135
    • Allal, A.S.1    Gervaz, P.2    Gertsch, P.3
  • 33
    • 20144362086 scopus 로고    scopus 로고
    • Impact of short-term preoperative radiotherapy on health-related quality of life and sexual functioning in primary rectal cancer: Report of a multicenter randomized trial
    • Marijnen CAM, van de Velde CJH, Putter H, et al. Impact of short-term preoperative radiotherapy on health-related quality of life and sexual functioning in primary rectal cancer: report of a multicenter randomized trial. J Clin Oncol 2005; 23:1847-1858.
    • (2005) J Clin Oncol , vol.23 , pp. 1847-1858
    • Marijnen, C.A.M.1    van de Velde, C.J.H.2    Putter, H.3
  • 34
    • 14944339251 scopus 로고    scopus 로고
    • Dietary counseling improves patient outcomes: A prospective, randomized, controlled trial in colorectal cancer patients undergoing radiotherapy
    • Ravasco P, Monteiro-Grillo I, Vidal PM, Camilo ME. Dietary counseling improves patient outcomes: a prospective, randomized, controlled trial in colorectal cancer patients undergoing radiotherapy. J Clin Oncol 2005; 23:1431-1438.
    • (2005) J Clin Oncol , vol.23 , pp. 1431-1438
    • Ravasco, P.1    Monteiro-Grillo, I.2    Vidal, P.M.3    Camilo, M.E.4
  • 35
    • 22144465168 scopus 로고    scopus 로고
    • Longitudinal quality of life and quality adjusted survival in a randomised controlled trial comparing six months of bolus fluorouracil/leucovorin vs. twelve weeks of protracted venous infusion fluorouracil as adjuvant chemotherapy for colorectal cancer
    • Chau I, Norman AR, Cunningham D, et al. Longitudinal quality of life and quality adjusted survival in a randomised controlled trial comparing six months of bolus fluorouracil/leucovorin vs. twelve weeks of protracted venous infusion fluorouracil as adjuvant chemotherapy for colorectal cancer. Eur J Cancer 2005; 41:1551-1559.
    • (2005) Eur J Cancer , vol.41 , pp. 1551-1559
    • Chau, I.1    Norman, A.R.2    Cunningham, D.3
  • 36
    • 33846990133 scopus 로고    scopus 로고
    • Quality of life in operable colon cancer patients receiving oral compared with intravenous chemotherapy: Results from National Surgical Adjuvant Breast and Bowel Project Trial C-06
    • This is a confirmation of the improvement of QoL during fluoropyrimidine adjuvant chemotherapy. It suggests that adverse effects of chemotherapy do not impact strongly on QoL
    • Kopec JA, Yothers G, Ganz PA, et al. Quality of life in operable colon cancer patients receiving oral compared with intravenous chemotherapy: results from National Surgical Adjuvant Breast and Bowel Project Trial C-06. J Clin Oncol 2007; 25:424-430. This is a confirmation of the improvement of QoL during fluoropyrimidine adjuvant chemotherapy. It suggests that adverse effects of chemotherapy do not impact strongly on QoL.
    • (2007) J Clin Oncol , vol.25 , pp. 424-430
    • Kopec, J.A.1    Yothers, G.2    Ganz, P.A.3
  • 38
    • 27944499893 scopus 로고    scopus 로고
    • A meta-analysis of two randomised trials of early chemotherapy in asymptomatic metastatic colorectal cancer
    • Ackland SP, Jones M, Tu D, et al. A meta-analysis of two randomised trials of early chemotherapy in asymptomatic metastatic colorectal cancer. Br J Cancer 2005; 93:1236-1243.
    • (2005) Br J Cancer , vol.93 , pp. 1236-1243
    • Ackland, S.P.1    Jones, M.2    Tu, D.3
  • 39
    • 33746608458 scopus 로고    scopus 로고
    • Ducreux M, Bouché O, Pignon JP, et al. Randomised trial comparing three different schedules of infusional 5FU and raltitrexed alone as first-line therapy in metastatic colorectal cancer. Final results of the Fédération Francophone de Cancérologie Digestive (FFCD) 9601 trial. Oncology 2006; 70:222-230. This study confirms the detrimental effect of raltitrexed as compared with fluoropyrimidines.
    • Ducreux M, Bouché O, Pignon JP, et al. Randomised trial comparing three different schedules of infusional 5FU and raltitrexed alone as first-line therapy in metastatic colorectal cancer. Final results of the Fédération Francophone de Cancérologie Digestive (FFCD) 9601 trial. Oncology 2006; 70:222-230. This study confirms the detrimental effect of raltitrexed as compared with fluoropyrimidines.
  • 40
    • 33645450153 scopus 로고    scopus 로고
    • Kemeny NE, Niedzwiecki D, Hollis DR, et al. Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481). J Clin Oncol 2006; 24:1395-1403. This was the first study demonstrating a QoL benefit for hepatic arterial infusion for unresectable hepatic metastases.
    • Kemeny NE, Niedzwiecki D, Hollis DR, et al. Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481). J Clin Oncol 2006; 24:1395-1403. This was the first study demonstrating a QoL benefit for hepatic arterial infusion for unresectable hepatic metastases.
  • 41
    • 33746626520 scopus 로고    scopus 로고
    • Arndt V, Merx H, Stegmaier C, et al. Restrictions in quality of life in colorectal cancer patients over three years after diagnosis: a population based study. Eur J Cancer 2006; 42:1848-1857. This was the first longitudinal population-based study on survivors, with an excellent participation rate of 82%.
    • Arndt V, Merx H, Stegmaier C, et al. Restrictions in quality of life in colorectal cancer patients over three years after diagnosis: a population based study. Eur J Cancer 2006; 42:1848-1857. This was the first longitudinal population-based study on survivors, with an excellent participation rate of 82%.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.