Treponema denticola induces interleukin-8 and macrophage chemoattractant protein 1 production in human umbilical vein epithelial cells

Microbes and Infection

Volumn 9, Issue 7, 2007, Pages 907-913

  Okuda, Tomoko ^a   Kimizuka, Ryuta ^a,b   Miyamoto, Meguru ^a   Kato, Tetsuo ^a,b   Yamada, Satoru ^a   Okuda, Katsuji ^a   Ishihara, Kazuyuki ^a,b  

^a TOKYO DENTAL COLLEGE   (Japan)

^b Tokyo Dental College   (Japan)

Author keywords

Atherosclerosis; Chemokine; Periodontitis; Protease; Treponema denticola

Indexed keywords

DENTILISIN; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; PERIODONTITIS; PRIORITY JOURNAL; TREPONEMA DENTICOLA; UMBILICAL VEIN;

CHEMOKINE CCL2; CHYMOTRYPSIN; ENDOTHELIAL CELLS; EPITHELIAL CELLS; HUMANS; INTERLEUKIN-8; PERIODONTITIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TREPONEMA DENTICOLA; UMBILICAL VEINS;

TREPONEMA DENTICOLA;

EID: 34249984120     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2007.03.009     Document Type: Article

References (42)

1. Socransky S.S., and Haffajee A.D. The bacterial etiology of destructive periodontal disease: current concepts. J. Periodontol. 63 (1992) 322-331
2. Wu T., Trevisan M., Genco R.J., Dorn J.P., Falkner K.L., and Sempos C.T. Periodontal disease and risk of cerebrovascular disease: the first national health and nutrition examination survey and its follow-up study. Arch. Intern. Med. 160 (2000) 2749-2755
3. Beck J.D., Eke P., Lin D., Madianos P., Couper D., Moss K., Elter J., Heiss G., and Offenbacher S. Associations between IgG antibody to oral organisms and carotid intima-medial thickness in community-dwelling adults. Atherosclerosis 183 (2005) 342-348
4. Lalla E., Lamster I.B., Hofmann M.A., Bucciarelli L., Jerud A.P., Tucker S., Lu Y., Papapanou P.N., and Schmidt A.M. Oral infection with a periodontal pathogen accelerates early atherosclerosis in apolipoprotein E-null mice. Arterioscler. Thromb. Vasc. Biol. 23 (2003) 1405-1411
5. Beilke M.A. Vascular endothelium in immunology and infectious disease. Rev. Infect. Dis. 11 (1989) 273-283
6. Cines D.B., Pollak E.S., Buck C.A., Loscalzo J., Zimmerman G.A., McEver R.P., Pober J.S., Wick T.M., Konkle B.A., Schwartz B.S., Barnathan E.S., McCrae K.R., Hug B.A., Schmidt A.M., and Stern D.M. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 91 (1998) 3527-3561
7. Leonard E.J., and Yoshimura T. Human monocyte chemoattractant protein-1 (MCP-1). Immunol. Today 11 (1990) 97-101
8. Baggiolini M., Dewald B., and Moser B. Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines, Adv. Immunol. 55 (1994) 97-179
9. Sakai A., Ohshima M., Sugano N., Otsuka K., and Ito K. Profiling the cytokines in gingival crevicular fluid using a cytokine antibody array. J. Periodontol. 77 (2006) 856-864
10. Emingil G., Atilla G., and Huseyinov A. Gingival crevicular fluid monocyte chemoattractant protein-1 and RANTES levels in patients with generalized aggressive periodontitis. J. Clin. Periodontol. 31 (2004) 829-834
11. Kurtis B., Tuter G., Serdar M., Akdemir P., Uygur C., Firatli E., and Bal B. Gingival crevicular fluid levels of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha in patients with chronic and aggressive periodontitis. J. Periodontol. 76 (2005) 1849-1855
12. Yu X., Antoniades H.N., and Graves D.T. Expression of monocyte chemoattractant protein 1 in human inflamed gingival tissues. Infect. Immun. 61 (1993) 4622-4628
13. Apostolopoulos J., Davenport P., and Tipping P.G. Interleukin-8 production by macrophages from atheromatous plaques. Arterioscler. Thromb. Vasc. Biol. 16 (1996) 1007-1012
14. Moreau M., Brocheriou I., Petit L., Ninio E., Chapman M.J., and Rouis M. Interleukin-8 mediates downregulation of tissue inhibitor of metalloproteinase-1 expression in cholesterol-loaded human macrophages: relevance to stability of atherosclerotic plaque. Circulation 99 (1999) 420-426
15. Namiki M., Kawashima S., Yamashita T., Ozaki M., Hirase T., Ishida T., Inoue N., Hirata K., Matsukawa A., Morishita R., Kaneda Y., and Yokoyama M. Local overexpression of monocyte chemoattractant protein-1 at vessel wall induces infiltration of macrophages and formation of atherosclerotic lesion: synergism with hypercholesterolemia. Arterioscler. Thromb. Vasc. Biol. 22 (2002) 115-120
16. Socransky S.S., Haffajee A.D., Cugini M.A., Smith C., and Kent R.L.J. Microbial complexes in subgingival plaque. J. Clin. Periodontol. 25 (1998) 134-144
17. Ishihara K., and Okuda K. Molecular analysis for pathogenicity of oral treponemes. Microbiol. Immunol. 43 (1999) 495-503
18. Ishihara K., Nabuchi A., Ito R., Miyachi K., Kuramitsu H.K., and Okuda K. Correlation between detection rates of periodontopathic bacterial DNA in carotid coronary stenotic artery plaque and in dental plaque samples. J. Clin. Microbiol. 42 (2004) 1313-1315
19. Haraszthy V.I., Zambon J.J., Trevisan M., Zeid M., and Genco R.J. Identification of periodontal pathogens in atheromatous plaques. J. Periodontol. 71 (2000) 1554-1560
20. Miyamoto M., Ishihara K., and Okuda K. The Treponema denticola surface protease dentilisin degrades interleukin-1b (IL-1b), IL-6, and tumor necrosis factor alpha. Infect. Immun. 74 (2006) 2462-2467
21. Yamazaki T., Miyamoto M., Yamada S., Okuda K., and Ishihara K. Surface protease of Treponema denticola hydrolyzes C3 and influences function of polymorphonuclear leukocytes. Microbes Infect. 8 (2006) 1758-1763
22. Ishihara K., Kuramitsu H.K., Miura T., and Okuda K. Dentilisin activity affects the organization of the outer sheath of Treponema denticola. J. Bacteriol. 180 (1998) 3837-3844
23. Ishihara K., Miura T., Kuramitsu H.K., and Okuda K. Characterization of the Treponema denticola prtP gene encoding a prolyl-phenylalanine-specific protease (dentilisin). Infect. Immun. 64 (1996) 5178-5186
24. Li A., Dubey S., Varney M.L., Dave B.J., and Singh R.K. IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J. Immunol. 170 (2003) 3369-3376
25. Baba A., Kadowaki T., Asao T., and Yamamoto K. Roles for Arg- and Lys-gingipains in the disruption of cytokine responses and loss of viability of human endothelial cells by Porphyromonas gingivalis infection. Biol. Chem. 383 (2002) 1223-1230
26. Asai Y., Jinno T., and Ogawa T. Oral treponemes and their outer membrane extracts activate human gingival epithelial cells through toll-like receptor 2. Infect. Immun. 71 (2003) 717-725
27. Choi E.K., Park S.A., Oh W.M., Kang H.C., Kuramitsu H.K., Kim B.G., and Kang I.C. Mechanisms of Porphyromonas gingivalis-induced monocyte chemoattractant protein-1 expression in endothelial cells. FEMS Immunol. Med. Microbiol. 44 (2005) 51-58
28. Nixon C.S., Steffen M.J., and Ebersole J.L. Cytokine responses to Treponema pectinovorum and Treponema denticola in human gingival fibroblasts. Infect. Immun. 68 (2000) 5284-5292
29. Deng Q.D., Han Y., Xia X., and Kuramitsu H.K. Effects of the oral spirochete Treponema denticola on interleukin-8 expression from epithelial cells. Oral Microbiol. Immunol. 16 (2001) 185-187
30. Asai Y., Ohyama Y., Gen K., and Ogawa T. Bacterial fimbriae and their peptides activate human gingival epithelial cells through Toll-like receptor 2. Infect. Immun. 69 (2001) 7387-7395
31. Yamazaki K., Nakajima T., Kubota Y., Gemmell E., Seymour G.J., and Hara K. Cytokine messenger RNA expression in chronic inflammatory periodontal disease. Oral Microbiol. Immunol. 12 (1997) 281-287
32. Jiang Y., Russell T.R., Graves D.T., Cheng H., Nong S.H., and Levitz S.M. Monocyte chemoattractant protein 1 and interleukin-8 production in mononuclear cells stimulated by oral microorganisms. Infect. Immun. 64 (1996) 4450-4455
33. Chae P., Im M., Gibson F., Jiang Y., and Graves D.T. Mice lacking monocyte chemoattractant protein 1 have enhanced susceptibility to an interstitial polymicrobial infection due to impaired monocyte recruitment. Infect. Immun. 70 (2002) 3164-3169
34. Herder C., Baumert J., Thorand B., Martin S., Lowel H., Kolb H., and Koenig W. Chemokines and incident coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. Arterioscler. Thromb. Vasc. Biol. 26 (2006) 2147-2152
35. Libby P. Inflammation in atherosclerosis. Nature 420 (2002) 868-874
36. Kinane D.F., Riggio M.P., Walker K.F., MacKenzie D., and Shearer B. Bacteraemia following periodontal procedures. J. Clin. Periodontol. 32 (2005) 708-713
37. Seinost G., Wimmer G., Skerget M., Thaller E., Brodmann M., Gasser R., Bratschko R.O., and Pilger E. Periodontal treatment improves endothelial dysfunction in patients with severe periodontitis. Am. Heart. J. 149 (2005) 1050-1054
38. Desvarieux M., Demmer R.T., Rundek T., Boden-Albala B., Jacobs Jr. D.R., Sacco R.L., and Papapanou P.N. Periodontal microbiota and carotid intima-media thickness: the oral infections and vascular disease epidemiology study (INVEST). Circulation 111 (2005) 576-582
39. Spahr A., Klein E., Khuseyinova N., Boeckh C., Muche R., Kunze M., Rothenbacher D., Pezeshki G., Hoffmeister A., and Koenig W. Periodontal infections and coronary heart disease: role of periodontal bacteria and importance of total pathogen burden in the coronary event and periodontal disease (CORODONT) study. Arch. Intern. Med. 166 (2006) 554-559
40. Iwai T., Inoue Y., Umeda M., Huang Y., Kurihara N., Koike M., and Ishikawa I. Oral bacteria in the occluded arteries of patients with Buerger disease. J. Vasc. Surg. 42 (2005) 107-115
41. Cavrini F., Sambri V., Moter A., Servidio D., Marangoni A., Montebugnoli L., Foschi F., Prati C., Di Bartolomeo R., and Cevenini R. Molecular detection of Treponema denticola and Porphyromonas gingivalis in carotid and aortic atheromatous plaques by FISH: report of two cases. J. Med. Microbiol. 54 (2005) 93-96
42. Beck J.D., Eke P., Heiss G., Madianos P., Couper D., Lin D., Moss K., Elter J., and Offenbacher S. Periodontal disease and coronary heart disease: a reappraisal of the exposure. Circulation 112 (2005) 19-24