Retinal vessel diameters and the role of inflammation in cerebrovascular disease

Annals of Neurology

Volumn 61, Issue 5, 2007, Pages 491-495

  De Jong, Frank Jan ^a,b   Ikram, M Kamran ^a   Witteman, Jacqueline C M ^a   Hofman, Albert ^a   De Jong, Paulus T V M ^a,b,c   Breteler, Monique M B ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; FIBRINOGEN; LIPOPROTEIN; PHOSPHOLIPASE A2;

ADULT; AGED; ARTICLE; BLOOD VESSEL DIAMETER; BRAIN MICROCIRCULATION; CEREBROVASCULAR DISEASE; COHORT ANALYSIS; FEMALE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; NEUROOPHTHALMOLOGY; POPULATION RESEARCH; PRIORITY JOURNAL; RETINA BLOOD VESSEL;

AGED; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CEREBROVASCULAR DISORDERS; COHORT STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; FIBRINOGEN; HUMANS; INFLAMMATION; MALE; MICROCIRCULATION; NETHERLANDS; OPHTHALMOSCOPY; PHOSPHOLIPASES A; PROSPECTIVE STUDIES; RETINAL VESSELS;

EID: 34249952154     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.21129     Document Type: Article

References (20)

1. Wong TY. Is retinal photography useful in the measurement of stroke risk? Lancet Neurol 2004;3:179-183.
2. Sharrett AR, Hubbard LD, Cooper LS, et al. Retinal arteriolar diameters and elevated blood pressure: the Atherosclerosis Risk in Communities Study. Am J Epidemiol 1999;150:263-270.
3. Wong TY, Klein R, Sharrett AR, et al. Cerebral white matter lesions, retinopathy, and incident clinical stroke. JAMA 2002; 288:67-74.
4. Wong TY, Klein R, Couper DJ, et al. Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study. Lancet 2001;358:1134-1140.
5. Ikram MK, De Jong FJ, Van Dijk EJ, et al. Retinal vessel diameters and cerebral small vessel disease: the Rotterdam Scan Study. Brain 2006;129:182-188.
6. Ikram MK, De Jong FJ, Bos M, et al. Retinal vessel diameters and risk of stroke: the Rotterdam Study. Neurology 2006;66: 1339-1343.
7. Ikram MK, de Jong FJ, Vingerling JR, et al. Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study. Invest Ophthalmol Vis Sci 2004;45:2129-2134.
8. Klein R, Klein BE, Knudtson MD, et al. Are inflammatory factors related to retinal vessel caliber? The Beaver Dam Eye Study. Arch Ophthalmol 2006;124:87-94.
9. Wong TY, Islam FM, Klein R, et al. Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA). Invest Ophthalmol Vis Sci 2006;47:2341-2350.
10. Ernst E, Resch KL. Fibrinogen as a cardiovascular risk factor: a meta-analysis and review of the literature. Ann Intern Med 1993;118:956-963.
11. Oei HH, van der Meer IM, Hofman A, et al. Lipoprotein-associated phospholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: the Rotterdam Study. Circulation 2005;111:570-575.
12. Tsimikas S, Willerson JT, Ridker PM. C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients. J Am Coll Cardiol 2006;47:C19-C31.
13. Hofman A, Grobbee DE, de Jong PT, van den Ouweland FA. Determinants of disease and disability in the elderly: the Rotterdam Elderly Study. Eur J Epidemiol 1991;7:403-422.
14. van Leeuwen R, Klaver CC, Vingerling JR, et al. The risk and natural course of age-related maculopathy: follow-up at 6 1/2 years in the Rotterdam study. Arch Ophthalmol 2003;121: 519-526.
15. Wolfs RC, Borger PH, Ramrattan RS, et al. Changing views on open-angle glaucoma: definitions and prevalences - The Rotterdam Study. Invest Ophthalmol Vis Sci 2000;41:3309-3321.
16. Hubbard LD, Brothers RJ, King WN, et al. Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology 1999;106:2269-2280.
17. Liew G, Wong TY, Mitchell P, Wang JJ. Are narrower or wider retinal venules associated with incident hypertension? Hypertension 2006;48:e10-e11.
18. Rader DJ. Inflammatory markers of coronary risk. N Engl J Med 2000;343:1179-1182.
19. Danesh J. Smoldering arteries? Low-grade inflammation and coronary heart disease. JAMA 1999;282:2169-2171.
20. Vink H, Constantinescu AA, Spaan JA. Oxidized lipoproteins degrade the endothelial surface layer: implications for platelet-endothelial cell adhesion. Circulation 2000;101:1500-1502.