Seco-pregnane steroids target the subgenomic RNA of alphavirus-like RNA viruses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 19, 2007, Pages 8083-8088

  Li, Yanmei ^a,b,e   Wang, Lihua ^c   Li, Shunlin ^a   Chen, Xiaoying ^b   Shen, Yuemao ^a   Zhang, Zhongkai ^d   He, Hongping ^a   Xu, Wenbo ^c   Shu, Yuelong ^c   Liang, Guodong ^c   Fang, Rongxiang ^b   Hao, Xiaojiang ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^c CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^d INSTITUTE OF MEDICINAL PLANTS   (China)

^e UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Antiviral drugs; Cynanchum atratum; Strobilanthes cusia

Indexed keywords

CYANATROSIDE A; GLAUCOGENIN C; GLYCOSIDE; PANICULATUMOSIDE C; PANICULATUMOSIDE D; PANICULATUMOSIDE E; PHYTOSTEROL; PREGNANE DERIVATIVE; STEROID; UNCLASSIFIED DRUG; VIRUS RNA; ANTIVIRUS AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; CYANCHUM ATRATUM; CYTOPATHOGENIC EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; EASTERN EQUINE ENCEPHALOMYELITIS VIRUS; GETAH VIRUS; HOST CELL; HUMAN; HUMAN CELL; MEDICINAL PLANT; MOUSE; NEWBORN; NONHUMAN; PLANT DISEASE; PRIORITY JOURNAL; RNA VIRUS; SINDBIS VIRUS; STROBILANTHES CUSIA; TOBACCO MOSAIC VIRUS; TRADITIONAL MEDICINE; VIRUS CELL INTERACTION; VIRUS GENOME; VIRUS INFECTION; VIRUS INHIBITION; ALPHA VIRUS; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HAMSTER; VIRUS REPLICATION;

ALPHAVIRUS; ANIMALIA; BAPHICACANTHUS CUSIA; CYNANCHUM ATRATUM; CYNANCHUM PANICULATUM; DNA VIRUSES; EASTERN EQUINE ENCEPHALITIS VIRUS; GETAH VIRUS; MUS; RNA VIRUSES; SINDBIS VIRUS; TOBACCO MOSAIC VIRUS;

ALPHAVIRUS; ALPHAVIRUS INFECTIONS; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MICE, INBRED BALB C; PREGNANES; RNA, VIRAL; SINDBIS VIRUS; TOBACCO MOSAIC VIRUS; VIRUS REPLICATION;

EID: 34249951994     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0702398104     Document Type: Article

References (38)

1. De Clercq E (2005) Curr Opin Microbiol 8:552-560.
2. Crumpacker C (2001) in Fields Virology, eds Knipe DM, Howley PM (Williams & Wilkins, Philadephia), pp 393-433.
3. De Clercq E (2001) J Pharmacol Exp Ther 297:1-10.
4. De Clercq E (2002) Nat Rev Drug Discov 1:13-25.
5. De Clercq E (2004) Nat Rev Microbiol 2:704-720.
6. Dixon RA (2001) Nature 411:843-847.
7. Chinese Pharmacopoeia Commission (2005) in Chinese Pharmacopoeia, ed Chinese Pharmacopoeia Commission (Chemical Industry Press, Beijing, China).
8. College NM (1979) in Zhong Yao Da Cidian (Shanghai Scientific and Technological Press, Shanghai, China), ed College NM, pp 1250-1252 and 1894-1895.
9. Mak NK, Leung CY, Wei XY, Shen XL, Wong RN, Leung KN, Fung MC (2004) Biochemical Pharmacology 67:167-174.
10. Ko HC, Wei BL, Chiou WF (2006) J Ethnopharmacol 107:205-210.
11. Nakagawa T, Hayashi K, Mitsuhashi H (1983) Chem Pharm Bull 31:870-878.
12. Zhang ZX, Zhou J, Hayashi K, Mitsuhashi H (1985) Chem Pharm Bull (Tokyo) 33:1507-1514.
13. Shivprasad S, Pogue GP, Lewandowski DJ, Hidalgo J, Donson J, Grill LK, Dawson WO (1999) Virology 255:312-323.
14. Dawson WO, Bubrick P, Grantham GL (1988) Phytopathology 78:783-789.
15. Saito T, Yamanaka K, Okada Y (1990) Virology 176:329-336.
16. Deom CM, Oliver MJ, Beachy RN (1987) Science 237:389-394.
17. Hunter TR, Hunt T, Knowland J, Zimmern D (1976) Nature 260:759-764.
18. Siegel A, Hari V, Montgomery I, Kolacz K (1976) Virology 73:363-371.
19. Beachy RN, Zaitlin M (1977) Virology 81:160-169.
20. Thomas CM, Tang S, Hammond-Kosack K, Jones J D (2000) Mol Plant-Microbe Interact 13:465-469.
21. Roger H (2002) in Matthews' Plant Virology (Academy Press, London, UK).
22. De Clercq E (2000) Med Res Rev 20:323-349.
23. Fujiwara M, Ijichi K, Tohuhisa K, Katsuura K, Wang G-Y-S, Uemura D, Shigeta S, Konno K, Yokota T, Baba M (1996) Antiviral Chem Chemother 7:230-236.
24. Fujioka T, Kashiwada Y, Kilkuskie RE, Cosentino LM, Ballas LM, Jiang JB, Janzen WP, Chen IS, Lee KH (1994) J Nat Prod 57:243-247.
25. Kashiwada Y, Hashimoto F, Cosentino LM, Chen CH, Garrett PE, Lee KH (1996) J Med Chem 39:1016-1017.
26. Meruelo D, Lavie G, Lavie D (1988) Proc Natl Acad Sci USA 85:5230-5234.
27. Lavie G, Valentine F, Levin B, Mazur Y, Gallo G, Lavie D, Weiner D, Meruelo D (1989) Proc Natl Acad Sci USA 86:5963-5967.
28. An T, Huang RQ, Yang Z, Zhang DK, Li GR, Yao YC, Gao J (2001) Phytochemistry 58:1267-1269.
29. Goldbach R, Olivier Le Gall O, Wellink J (1991) Semin Virol 2:19-25.
30. Siegel RW, Adkins S, Kao CC (1997) Proc Natl Acad Sci USA 94:11238-11243.
31. Wielgosz MM, Raju R, Huang HV (2001) J Virol 75:3509-3519.
32. Watanabe Y, Kishibayashi N, Motoyoshi F, Okada Y (1987) Virology 161:527-532.
33. Bradford MM (1976) Anal Biochem 72:248-254.
34. Wu CY, Jan JT, Ma SH, Kuo CJ, Juan HF, Cheng YS, Hsu HH, Huang HC, Wu D, Brik A, et al. (2004) Proc Natl Acad Sci USA 101:10012-10017.
35. Sambrook J, Fritsch EF, Maniatis T (1989) in Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Lab Press, Plainview, NY).
36. Liang GD, Li L, Zhou GL, Fu SH, Li QP, Li FS, He HH, Jin Q, He Y, Chen BQ, et al. (2000) J Gen Virol 81:1347-1351.
37. Williams-Aziz SL Hartline CB, Harden EA, Daily SL, Prichard MN, Kushner NL, Beadle JR, Wan WB, Hostetler KY, Kern ER (2005) Antimicrob Agents Chemother 49:3724-3733.
38. Wielgosz MM, Huang HV (1997) J Virol 71:9108-9117.