Mutagenesis of the herpesvirus saimiri terminal repeat region reveals important elements for virus production

Journal of Virology

Volumn 81, Issue 12, 2007, Pages 6765-6770

  White, Robert E ^a   Carline, Lindsay ^a   Allday, Martin J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CONTROLLED STUDY; EPISOME; HERPES VIRUS SAIMIRI; LIFE CYCLE; LONG TERMINAL REPEAT; MONKEY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; VIRUS GENOME; VIRUS REPLICATION;

ANIMALS; AOTIDAE; BASE SEQUENCE; CELL LINE; CHROMOSOMES, ARTIFICIAL, BACTERIAL; GENE DELETION; GENETIC COMPLEMENTATION TEST; GENOME, VIRAL; HERPESVIRUS 2, SAIMIRIINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PLASMIDS; RECOMBINANT PROTEINS; TERMINAL REPEAT SEQUENCES; VIRUS REPLICATION;

BACTERIA (MICROORGANISMS); SAIMIRIINE HERPESVIRUS 2;

EID: 34249949627     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02579-06     Document Type: Article

References (21)

1. Albrecht, J. C., J. Nicholas, D. Biller, K. R. Cameron, B. Biesinger, C. Newman, S. Wittmann, M. A. Craxton, H. Coleman, B. Fleckenstein, et al. 1992. Primary structure of the herpesvirus saimiri genome. J. Virol. 66:5047-5058.
2. Ballestas, M. E., and K. M. A. Kaye. 2001. Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cis-acting terminal repeat (TR) sequence and specifically binds TR DNA. J. Virol. 75:3250-3258.
3. Ballestas, M. E., P. A. Chatis, and K. M. Kaye. 1999. Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen. Science 284:641-644.
4. Bankier, A. T., W. Dietrich, R. Baer, B. G. Barrell, F. Colbere-Garapin, B. Fleckenstein, and W. Bodemer. 1985. Terminal repetitive sequences in herpesvirus saimiri virion DNA. J. Virol. 55:133-139.
5. Bloss, T. A., and B. Sugden. 1994. Optimal lengths for DNAs encapsidated by Epstein-Barr virus. J. Virol. 68:8217-8222.
6. Bornkamm, G. W., H. Delius, B. Fleckenstein, F. J. Werner, and C. Mulder. 1976. Structure of herpesvirus saimiri genomes: arrangement of heavy and light sequences in the M genome. J. Virol. 19:154-161.
7. Calderwood, M., R. E. White, R. A. Griffiths, and A. Whitehouse. 2005. Open reading frame 73 is required for herpesvirus saimiri A11-S4 episomal persistence. J. Gen. Virol. 86:2703-2708.
8. Collins, C. M., M. M. Medveczky, T. Lund, and P. G. Medveczky. 2002. The terminal repeats and latency-associated nuclear antigen of herpesvirus saimiri are essential for episomal persistence of the viral genome. J. Gen. Virol. 83:2269-2278.
9. Delecluse, H. J., D. Pich, T. Hilsendegen, C. Baum, and W. Hammerschmidt. 1999. A first-generation packaging cell line for Epstein-Barr virus-derived vectors. Proc. Natl. Acad. Sci. USA 96:5188-5193.
10. Deng, H., J. T. Chu, N. H. Park, and R. Sun. 2004. Identification of cis sequences required for lytic DNA replication and packaging of murine gammaherpesvirus 68. J. Virol. 78:9123-9131.
11. Fowler, P., S. Marques, J. P. Simas, and S. Efstathiou. 2003. ORF73 of murine herpesvirus-68 is critical for the establishment and maintenance of latency. J. Gen. Virol. 84:3405-3416.
12. Hart, S. L., C. V. Arancibia-Carcamo, M. A. Wolfert, C. Mailhos, N. J. O'Reilly, R. R. Ali, C. Coutelle, A. J. George, R. P. Harbottle, A. M. Knight, D. F. Larkin, R. J. Levinsky, L. W. Seymour, A. J. Thrasher, and C. Kinnon. 1998. Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector. Hum. Gene Ther. 9:575-585.
13. Kanda, T., K. F. Sullivan, and G. M. Wahl. 1998. Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells. Curr. Biol. 8:377-385.
14. Lalioti, M., and J. Heath. 2001. A new method for generating point mutations in bacterial artificial chromosomes by homologous recombination in Escherichia coli. Nucleic Acids Res. 29:E14.
15. Monier, K., J. C. Armas, S. Etteldorf, P. Ghazal, and K. F. Sullivan. 2000. Annexation of the interchromosomal space during viral infection. Nat. Cell Biol. 2:661-665.
16. Stamminger, T., R. W. Honess, D. F. Young, W. Bodemer, E. D. Blair, and B. Fleckenstein. 1987. Organization of terminal reiterations in the virion DNA of herpesvirus saimiri. J. Gen. Virol. 68:1049-1066.
17. Verma, S. C., and E. S. Robertson. 2003. ORF73 of herpesvirus saimiri strain C488 tethers the viral genome to metaphase chromosomes and binds to cis-acting DNA sequences in the terminal repeats. J. Virol. 77:12494-12506.
18. Werner, F. J., G. W. Bornkamm, and B. Fleckenstein. 1977. Episomal viral DNA in a herpesvirus saimiri-transformed lymphoid cell line. J. Virol. 22: 794-803.
19. White, R. E., M. A. Calderwood, and A. Whitehouse. 2003. Generation and precise modification of a herpesvirus saimiri bacterial artificial chromosome demonstrates that the terminal repeats are required for both virus production and episomal persistence. J. Gen. Virol. 84:3393-3403.
20. White, R. E., R. Wade-Martins, S. L. Hart, J. Frampton, B. Huey, A. Desai-Mehta, K. M. Cerosaletti, P. Concannon, and M. R. James. 2003. Functional delivery of large genomic DNA to human cells with a peptide-lipid vector. J. Gene Med. 5:883-892.
21. Zimmermann, J., and W. Hammerschmidt. 1995. Structure and role of the terminal repeats of Epstein-Barr virus in processing and packaging of virion DNA. J. Virol. 69:3147-3155.