-
1
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y., Swensen J., Shattuck-Eidens D., Futreal P.A., Harshman K., Tavtigian S., Liu Q., Cochran C., Bennett L.M., Ding W., et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266 (1994) 66-71
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
Tavtigian, S.6
Liu, Q.7
Cochran, C.8
Bennett, L.M.9
Ding, W.10
-
2
-
-
0028073794
-
BRCA1 mutations in primary breast and ovarian carcinomas
-
Futreal P.A., Liu Q., Shattuck-Eidens D., Cochran C., Harshman K., Tavtigian S., Bennett L.M., Haugen-Strano A., Swensen J., Miki Y., et al. BRCA1 mutations in primary breast and ovarian carcinomas. Science 266 (1994) 120-122
-
(1994)
Science
, vol.266
, pp. 120-122
-
-
Futreal, P.A.1
Liu, Q.2
Shattuck-Eidens, D.3
Cochran, C.4
Harshman, K.5
Tavtigian, S.6
Bennett, L.M.7
Haugen-Strano, A.8
Swensen, J.9
Miki, Y.10
-
3
-
-
2542543477
-
Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition
-
Mirkovic N., Marti-Renom M.A., Weber B.L., Sali A., and Monteiro A.N. Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition. Cancer Res. 64 (2004) 3790-3797
-
(2004)
Cancer Res.
, vol.64
, pp. 3790-3797
-
-
Mirkovic, N.1
Marti-Renom, M.A.2
Weber, B.L.3
Sali, A.4
Monteiro, A.N.5
-
4
-
-
0034194328
-
Functional assay for BRCA1: mutagenesis of the COOH-terminal region reveals critical residues for transcription activation
-
Hayes F., Cayanan C., Barilla D., and Monteiro A.N. Functional assay for BRCA1: mutagenesis of the COOH-terminal region reveals critical residues for transcription activation. Cancer Res. 60 (2000) 2411-2418
-
(2000)
Cancer Res.
, vol.60
, pp. 2411-2418
-
-
Hayes, F.1
Cayanan, C.2
Barilla, D.3
Monteiro, A.N.4
-
5
-
-
0030850687
-
Common BRCA1 variants and transcriptional activation
-
Monteiro A.N., August A., and Hanafusa H. Common BRCA1 variants and transcriptional activation. Am. J. Hum. Genet. 61 (1997) 761-762
-
(1997)
Am. J. Hum. Genet.
, vol.61
, pp. 761-762
-
-
Monteiro, A.N.1
August, A.2
Hanafusa, H.3
-
6
-
-
0030915448
-
Human BRCA1 inhibits growth in yeast: potential use in diagnostic testing
-
Humphrey J.S., Salim A., Erdos M.R., Collins F.S., Brody L.C., and Klausner R.D. Human BRCA1 inhibits growth in yeast: potential use in diagnostic testing. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 5820-5825
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 5820-5825
-
-
Humphrey, J.S.1
Salim, A.2
Erdos, M.R.3
Collins, F.S.4
Brody, L.C.5
Klausner, R.D.6
-
7
-
-
0034809456
-
Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1
-
Williams R.S., Green R., and Glover J.N. Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1. Nat. Struct. Biol. 8 (2001) 838-842
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 838-842
-
-
Williams, R.S.1
Green, R.2
Glover, J.N.3
-
8
-
-
0037099666
-
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor
-
Derbyshire D.J., Basu B.P., Serpell L.C., Joo W.S., Date T., Iwabuchi K., and Doherty A.J. Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor. EMBO J. 21 (2002) 3863-3872
-
(2002)
EMBO J.
, vol.21
, pp. 3863-3872
-
-
Derbyshire, D.J.1
Basu, B.P.2
Serpell, L.C.3
Joo, W.S.4
Date, T.5
Iwabuchi, K.6
Doherty, A.J.7
-
9
-
-
0346101743
-
Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains
-
Rodriguez M., Yu X., Chen J., and Songyang Z. Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains. J. Biol. Chem. 278 (2003) 52914-52918
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52914-52918
-
-
Rodriguez, M.1
Yu, X.2
Chen, J.3
Songyang, Z.4
-
10
-
-
0142147272
-
The BRCT domain is a phospho-protein binding domain
-
Yu X., Chini C.C., He M., Mer G., and Chen J. The BRCT domain is a phospho-protein binding domain. Science 302 (2003) 639-642
-
(2003)
Science
, vol.302
, pp. 639-642
-
-
Yu, X.1
Chini, C.C.2
He, M.3
Mer, G.4
Chen, J.5
-
11
-
-
0034674706
-
Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor
-
Yu X., and Baer R. Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor. J. Biol. Chem. 275 (2000) 18541-18549
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18541-18549
-
-
Yu, X.1
Baer, R.2
-
12
-
-
6344264992
-
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
-
Yu X., and Chen J. DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains. Mol. Cell Biol. 24 (2004) 9478-9486
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 9478-9486
-
-
Yu, X.1
Chen, J.2
-
13
-
-
2542489188
-
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
-
Clapperton J.A., Manke I.A., Lowery D.M., Ho T., Haire L.F., Yaffe M.B., and Smerdon S.J. Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer. Nat. Struct. Mol. Biol. 11 (2004) 512-518
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 512-518
-
-
Clapperton, J.A.1
Manke, I.A.2
Lowery, D.M.3
Ho, T.4
Haire, L.F.5
Yaffe, M.B.6
Smerdon, S.J.7
-
14
-
-
2342484423
-
Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling
-
Shiozaki E.N., Gu L., Yan N., and Shi Y. Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling. Mol. Cell 14 (2004) 405-412
-
(2004)
Mol. Cell
, vol.14
, pp. 405-412
-
-
Shiozaki, E.N.1
Gu, L.2
Yan, N.3
Shi, Y.4
-
15
-
-
2542490186
-
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
-
Williams R.S., Lee M.S., Hau D.D., and Glover J.N. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat. Struct. Mol. Biol. 11 (2004) 519-525
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 519-525
-
-
Williams, R.S.1
Lee, M.S.2
Hau, D.D.3
Glover, J.N.4
-
16
-
-
23944510641
-
Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex
-
Varma A.K., Brown R.S., Birrane G., and Ladias J.A. Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex. Biochemistry 44 (2005) 10941-10946
-
(2005)
Biochemistry
, vol.44
, pp. 10941-10946
-
-
Varma, A.K.1
Brown, R.S.2
Birrane, G.3
Ladias, J.A.4
-
17
-
-
3142608985
-
Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains
-
Botuyan M.V., Nomine Y., Yu X., Juranic N., Macura S., Chen J., and Mer G. Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains. Structure (Camb.) 12 (2004) 1137-1146
-
(2004)
Structure (Camb.)
, vol.12
, pp. 1137-1146
-
-
Botuyan, M.V.1
Nomine, Y.2
Yu, X.3
Juranic, N.4
Macura, S.5
Chen, J.6
Mer, G.7
-
18
-
-
0030474170
-
Evidence for a transcriptional activation function of BRCA1 C-terminal region
-
Monteiro A.N., August A., and Hanafusa H. Evidence for a transcriptional activation function of BRCA1 C-terminal region. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 13595-13599
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 13595-13599
-
-
Monteiro, A.N.1
August, A.2
Hanafusa, H.3
-
19
-
-
0029830051
-
Transcriptional activation by BRCA1
-
Chapman M.S., and Verma I.M. Transcriptional activation by BRCA1. Nature 382 (1996) 678-679
-
(1996)
Nature
, vol.382
, pp. 678-679
-
-
Chapman, M.S.1
Verma, I.M.2
-
20
-
-
20644461718
-
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function
-
Cantor S.B., Bell D.W., Ganesan S., Kass E.M., Drapkin R., Grossman S., Wahrer D.C., Sgroi D.C., Lane W.S., Haber D.A., and Livingston D.M. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell 105 (2001) 149-160
-
(2001)
Cell
, vol.105
, pp. 149-160
-
-
Cantor, S.B.1
Bell, D.W.2
Ganesan, S.3
Kass, E.M.4
Drapkin, R.5
Grossman, S.6
Wahrer, D.C.7
Sgroi, D.C.8
Lane, W.S.9
Haber, D.A.10
Livingston, D.M.11
-
21
-
-
0033574543
-
Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage
-
Li S., Chen P.L., Subramanian T., Chinnadurai G., Tomlinson G., Osborne C.K., Sharp Z.D., and Lee W.H. Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage. J. Biol. Chem. 274 (1999) 11334-11338
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11334-11338
-
-
Li, S.1
Chen, P.L.2
Subramanian, T.3
Chinnadurai, G.4
Tomlinson, G.5
Osborne, C.K.6
Sharp, Z.D.7
Lee, W.H.8
-
22
-
-
0032566753
-
The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
-
Yu X., Wu L.C., Bowcock A.M., Aronheim A., and Baer R. The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression. J. Biol. Chem. 273 (1998) 25388-25392
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25388-25392
-
-
Yu, X.1
Wu, L.C.2
Bowcock, A.M.3
Aronheim, A.4
Baer, R.5
-
23
-
-
0037462647
-
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
-
Williams R.S., and Glover J.N. Structural consequences of a cancer-causing BRCA1-BRCT missense mutation. J. Biol. Chem. 278 (2003) 2630-2635
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2630-2635
-
-
Williams, R.S.1
Glover, J.N.2
-
24
-
-
0037044567
-
Germ line BRCA1 and BRCA2 mutations in Greek breast/ovarian cancer families: 5382insC is the most frequent mutation observed
-
Ladopoulou A., Kroupis C., Konstantopoulou I., Ioannidou-Mouzaka L., Schofield A.C., Pantazidis A., Armaou S., Tsiagas I., Lianidou E., Efstathiou E., Tsionou C., Panopoulos C., Mihalatos M., Nasioulas G., Skarlos D., Haites N.E., Fountzilas G., Pandis N., and Yannoukakos D. Germ line BRCA1 and BRCA2 mutations in Greek breast/ovarian cancer families: 5382insC is the most frequent mutation observed. Cancer Lett. 185 (2002) 61-70
-
(2002)
Cancer Lett.
, vol.185
, pp. 61-70
-
-
Ladopoulou, A.1
Kroupis, C.2
Konstantopoulou, I.3
Ioannidou-Mouzaka, L.4
Schofield, A.C.5
Pantazidis, A.6
Armaou, S.7
Tsiagas, I.8
Lianidou, E.9
Efstathiou, E.10
Tsionou, C.11
Panopoulos, C.12
Mihalatos, M.13
Nasioulas, G.14
Skarlos, D.15
Haites, N.E.16
Fountzilas, G.17
Pandis, N.18
Yannoukakos, D.19
-
25
-
-
0034734384
-
The BRCA1 C-terminal domain: structure and function
-
Huyton T., Bates P.A., Zhang X., Sternberg M.J., and Freemont P.S. The BRCA1 C-terminal domain: structure and function. Mutat. Res. 460 (2000) 319-332
-
(2000)
Mutat. Res.
, vol.460
, pp. 319-332
-
-
Huyton, T.1
Bates, P.A.2
Zhang, X.3
Sternberg, M.J.4
Freemont, P.S.5
-
26
-
-
0036317926
-
Characterisation of the BRCT domains of the breast cancer susceptibility gene product BRCA1
-
Ekblad C.M., Wilkinson H.R., Schymkowitz J.W., Rousseau F., Freund S.M., and Itzhaki L.S. Characterisation of the BRCT domains of the breast cancer susceptibility gene product BRCA1. J. Mol. Biol. 320 (2002) 431-442
-
(2002)
J. Mol. Biol.
, vol.320
, pp. 431-442
-
-
Ekblad, C.M.1
Wilkinson, H.R.2
Schymkowitz, J.W.3
Rousseau, F.4
Freund, S.M.5
Itzhaki, L.S.6
-
27
-
-
15544387932
-
Thermal denaturation of the BRCT tandem repeat region of human tumour suppressor gene product BRCA1
-
Pyrpassopoulos S., Ladopoulou A., Vlassi M., Papanikolau Y., Vorgias C.E., Yannoukakos D., and Nounesis G. Thermal denaturation of the BRCT tandem repeat region of human tumour suppressor gene product BRCA1. Biophys. Chem. 114 (2005) 1-12
-
(2005)
Biophys. Chem.
, vol.114
, pp. 1-12
-
-
Pyrpassopoulos, S.1
Ladopoulou, A.2
Vlassi, M.3
Papanikolau, Y.4
Vorgias, C.E.5
Yannoukakos, D.6
Nounesis, G.7
-
28
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
30
-
-
0019840442
-
Thermal denaturation of streptomyces subtilisin inhibitor, subtilisin BPN′, and the inhibitor-subtilisin complex
-
Takahashi K., and Sturtevant J.M. Thermal denaturation of streptomyces subtilisin inhibitor, subtilisin BPN′, and the inhibitor-subtilisin complex. Biochemistry 20 (1981) 6185-6190
-
(1981)
Biochemistry
, vol.20
, pp. 6185-6190
-
-
Takahashi, K.1
Sturtevant, J.M.2
-
31
-
-
0026586591
-
Theoretical-analysis of Lumry-Eyring models in differential scanning calorimetry
-
Sanchez-Ruiz J.M. Theoretical-analysis of Lumry-Eyring models in differential scanning calorimetry. Biophys. J. 61 (1992) 921-935
-
(1992)
Biophys. J.
, vol.61
, pp. 921-935
-
-
Sanchez-Ruiz, J.M.1
-
32
-
-
0032546744
-
Dimer-to-tetramer transformation: loop excision dramatically alters structure and stability of the ROP four alpha-helix bundle protein
-
Lassalle M.W., Hinz H.J., Wenzel H., Vlassi M., Kokkinidis M., and Cesareni G. Dimer-to-tetramer transformation: loop excision dramatically alters structure and stability of the ROP four alpha-helix bundle protein. J. Mol. Biol. 279 (1998) 987-1000
-
(1998)
J. Mol. Biol.
, vol.279
, pp. 987-1000
-
-
Lassalle, M.W.1
Hinz, H.J.2
Wenzel, H.3
Vlassi, M.4
Kokkinidis, M.5
Cesareni, G.6
-
33
-
-
0035979373
-
Temperature-induced denaturation and renaturation of triosephosphate isomerase from Saccharomyces cerevisiae: evidence of dimerization coupled to refolding of the thermally unfolded protein
-
Benitez-Cardoza C.G., Rojo-Dominguez A., and Hernandez-Arana A. Temperature-induced denaturation and renaturation of triosephosphate isomerase from Saccharomyces cerevisiae: evidence of dimerization coupled to refolding of the thermally unfolded protein. Biochemistry 40 (2001) 9049-9058
-
(2001)
Biochemistry
, vol.40
, pp. 9049-9058
-
-
Benitez-Cardoza, C.G.1
Rojo-Dominguez, A.2
Hernandez-Arana, A.3
-
35
-
-
0029957505
-
The enthalpy change in protein folding and binding: refinement of parameters for structure-based calculations
-
Hilser V.J., Gomez J., and Freire E. The enthalpy change in protein folding and binding: refinement of parameters for structure-based calculations. Proteins 26 (1996) 123-133
-
(1996)
Proteins
, vol.26
, pp. 123-133
-
-
Hilser, V.J.1
Gomez, J.2
Freire, E.3
-
36
-
-
27844479167
-
Thermostability of irreversible unfolding alpha-amylases analyzed by unfolding kinetics
-
Duy C., and Fitter J. Thermostability of irreversible unfolding alpha-amylases analyzed by unfolding kinetics. J. Biol. Chem. 280 (2005) 37360-37365
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37360-37365
-
-
Duy, C.1
Fitter, J.2
-
37
-
-
0346101739
-
Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations
-
Williams R.S., Chasman D.I., Hau D.D., Hui B., Lau A.Y., and Glover J.N. Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations. J. Biol. Chem. 278 (2003) 53007-53016
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 53007-53016
-
-
Williams, R.S.1
Chasman, D.I.2
Hau, D.D.3
Hui, B.4
Lau, A.Y.5
Glover, J.N.6
-
38
-
-
33644549954
-
Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance
-
Chenevix-Trench G., Healey S., Lakhani S., Waring P., Cummings M., Brinkworth R., Deffenbaugh A.M., Burbidge L.A., Pruss D., Judkins T., Scholl T., Bekessy A., Marsh A., Lovelock P., Wong M., Tesoriero A., Renard H., Southey M., Hopper J.L., Yannoukakos K., Brown M., Easton D., Tavtigian S.V., Goldgar D., and Spurdle A.B. Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance. Cancer Res. 66 (2006) 2019-2027
-
(2006)
Cancer Res.
, vol.66
, pp. 2019-2027
-
-
Chenevix-Trench, G.1
Healey, S.2
Lakhani, S.3
Waring, P.4
Cummings, M.5
Brinkworth, R.6
Deffenbaugh, A.M.7
Burbidge, L.A.8
Pruss, D.9
Judkins, T.10
Scholl, T.11
Bekessy, A.12
Marsh, A.13
Lovelock, P.14
Wong, M.15
Tesoriero, A.16
Renard, H.17
Southey, M.18
Hopper, J.L.19
Yannoukakos, K.20
Brown, M.21
Easton, D.22
Tavtigian, S.V.23
Goldgar, D.24
Spurdle, A.B.25
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