Validation of three noninvasive laboratory variables to predict significant fibrosis and cirrhosis in patients with chronic hepatitis C in Saudi Arabia

Annals of Saudi Medicine

Volumn 27, Issue 2, 2007, Pages 89-93

  Abdo, Ayman A ^a   Al Swat, Khalid ^a   Azzam, Nahla ^a   Ahmed, Shaffi ^a   Al Faleh, Faleh ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE;

ADOLESCENT; ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; FEMALE; HEPATITIS C; HUMAN; HUMAN TISSUE; INFORMATION PROCESSING; INTERMETHOD COMPARISON; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; NON INVASIVE MEASUREMENT; PREDICTION; PRIORITY JOURNAL; ROC CURVE; SAUDI ARABIA; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; THROMBOCYTE COUNT; VALIDATION STUDY;

EID: 34249895879     PISSN: 02564947     EISSN: 13199226     Source Type: Journal    
DOI: 10.5144/0256-4947.2007.89     Document Type: Article

References (19)

1. Bravo A, Sheth S, Chopra S. Liver biopsy. N Eng J Med 2001; 344:495-500.
2. Pasha T, Gabriel S, Themeau T, Dickson E, Lindor K. Cost-effectiveness of ultrasound-guided liver biopsy. Hepatology 1998; 27:1220-1226.
3. Fontana R, Lok A. Noninvasive monitoring of patients with chronic hepatitis C. Hepatology 2002; 36:S57-S64.
4. Bonacini M, Hadi G, Govindarajan S, Lindsay K. Utility of a discriminant score for diagnosing advanced fibrosis or cirrhosis in patients with chronic hepatitis C virus infection. Am J Gastroenterol 1997; 92:1302-1304.
5. Pohl A, Behling C, Oliver D, Kilani M, Monson P, Hassanein T. Serum aminotransferase levels and platelet count as predictors of degree of fibrosis in chronic hepatitis C virus infectrion. Am J Gastroenterol 2001; 96:3142-3146.
6. Forns X, Ampurdanes S, Llovet J, Aponte J, Quinto L, Martinez-Bauer E et al. Identification of chronic hepatitis C patients without hepatic fibrosis by simple predictive model. Hepatology 2002; 36:986-992
7. Castera L, Vergniol J, Foucher J, Bail B, Chanteloup E, Haaser M et al. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chonic hepatitis C. Gastroenterology 2005; 128:343-350.
8. Rosenberg W, Voelker M, Thiel R, Becka M, Burt A, Schuppan D. Serum markers detect the presence of liver fibrosis: A cohort study. Gastroenterology 2004; 127:1704-1713.
9. Imbert-Bismut F, Ratziu V, Charlotte F, Benhamou Y, Poynard T. Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Lancet 2001; 357:1069-1075.
10. Bedossa P, Poynard T. An algorithm for grading activity in chronic hepatitis C. Hepatology 1996; 24:289-293.
11. Seeff L Natural history of chronic hepatitis C. Hepatology 2002; 36:S35-S46.
12. Dienstag J. The role of liver biopsy in chronic hepatitis C. Hepatology 2002; 36:S152-S160.
13. Murawaki Y, Koda M, Okamoto K, Mimura K, Kawasaki H. Diagnostic value of serum type 4 collagen test in comparison with platelet count for predicting the fibrotic stage in patients with chronic hepatitis C. J Gastroenterol Hepatol 2001; 16:727-781.
14. Renou C, Muller P, Jouve E, Bertrand J, Raoult A, Benderriter T et al. Relevance of moderate isolated thrombopenia as a strong predictive marker of cirrhosis in patients with chronic hepatitis C virus. Am J Gastroenterol 2001; 96:1657-1659.
15. Poynard T, Bedossa P. METAVIR and CLINIVIR cooperative study groups. Age and platelet count a simple index for predicting the presence of histological lesions in patients with antibodies to hepatitis C virus. J Viral Hepat 1997; 4:199-208.
16. Sheth S, Flamm S, Gorgon F, Chopra S. AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection. Am J Gastroenterol 1998; 93:44-48.
17. Park G, Lin B, Ngu M, Jones D, Katelaris P. Aspirtate aminotransferase:alanine aminotransferase ratio in chronic hepatitis C infection: is it a useful predictir of cirrhosis? J Gastroenterol Hepatol 2000; 15:386-390.
18. Imperiale T, Said A, Cummings O, Born L. Need for validation of clinical decision aids: use of the AST/ALT ratio in predicting cirrhosis in chronic hepatitis C. Am J Gastroenterol 2000; 95:2328-2332.
19. Wai C, Greenson J, Fontana R, Kalbfleisch J, Marrero J, Conjeevaram H et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 2003; 38:518-526.