Gating of the HypoPP-1 mutations: II. Effects of a calcium-channel agonist BayK 8644

Pflugers Archiv European Journal of Physiology

Volumn 454, Issue 4, 2007, Pages 605-614

  Kuzmenkin, Alexey ^a,b   Hang, Chao ^a   Kuzmenkina, Elza ^a   Jurkat Rott, Karin ^a  

^a UNIVERSITY OF ULM   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

BayK 8644; Cooperativity; Gating model; Global fitting; Hypokalemic periodic paralysis; Second open state

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL STIMULATING AGENT; VOLTAGE GATED CALCIUM CHANNEL;

ARTICLE; CATALYST; CELL MEMBRANE DEPOLARIZATION; CHANNEL GATING; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; HYPOKALEMIC PERIODIC PARALYSIS; ION CURRENT; PATCH CLAMP; PRIORITY JOURNAL; RABBIT; WHOLE CELL; WILD TYPE;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNELS, L-TYPE; CELL LINE; HUMANS; HYPOKALEMIC PERIODIC PARALYSIS; ION CHANNEL GATING; OXYGEN; PATCH-CLAMP TECHNIQUES;

EID: 34249884509     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0228-0     Document Type: Article

References (22)

1. Erxleben C, Gomez-Alegria C, Darden T, Mori Y, Birnbaumer L, Armstrong DL (2003) Modulation of cardiac Ca(V)1.2 channels by dihydropyridine and phosphatase inhibitor requires Ser-1142 in the domain III pore loop. Proc Natl Acad Sci USA 100:2929-2934
2. Fass DM, Levitan ES (1996) L-type Ca2+ channels access multiple open states to produce two components of Bay K 8644-dependent current in GH3 cells. J Gen Physiol 108:13-26
3. Fleig A, Takeshima H, Penner R (1996) Absence of Ca2+ current facilitation in skeletal muscle of transgenic mice lacking the type 1 ryanodine receptor. J Physiol 496:339-345
4. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391:85-100
5. Hess P, Lansman JB, Tsien RW (1984) Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature 311:538-544
6. Hivert B, Luvisetto S, Navangione A, Tottene A, Pietrobon D (1999) Anomalous L-type calcium channels of rat spinal motoneurons. J Gen Physiol 113:679-694
7. Hoshi T, Smith SJ (1987) Large depolarization induces long openings of voltage-dependent calcium channels in adrenal chromaffin cells. J Neurosci 7:571-580
8. Hui K, Gardzinski P, Sun HS, Backx PH, Feng ZP (2005) Permeable ions differentially affect gating kinetics and unitary conductance of L-type calcium channels. Biochem Biophys Res Commun 338:783-792
9. Josephson IR, Guia A, Lakatta EG, Stern MD (2002) Modulation of the conductance of unitary cardiac L-type Ca(2+) channels by conditioning voltage and divalent ions. Biophys J 83:2587-2594
10. Josephson IR, Guia A, Lakatta EG, Stern MD (2002) Modulation of the gating of unitary cardiac L-type Ca(2+) channels by conditioning voltage and divalent ions. Biophys J 83:2575-2586
11. Kuzmenkin A, Hang C, Kuzmenkina E, Jurkat-Rott K (2007) Gating of the HypoPP-1 mutations: I. Mutant-specific effects and cooperativity. Pflügers Arch
12. Lerche H, Klugbauer N, Lehmann-Horn F, Hofmann F, Melzer W (1996) Expression and functional characterization of the cardiac L-type calcium channel carrying a skeletal muscle DHP-receptor mutation causing hypokalaemic periodic paralysis. Pflugers Arch 431:461-463
13. McFarlane MB (1997) Depolarization-induced slowing of Ca2+ channel deactivation in squid neurons. Biophys J 72:1607-1621
14. Morrill JA, Cannon SC (1999) Effects of mutations causing hypokalaemic periodic paralysis on the skeletal muscle L-type Ca2+ channel expressed in Xenopus laevis oocytes. J Physiol 520:321-336
15. Morrill JA, Brown RH Jr, Cannon SC (1998) Gating of the L-type Ca channel in human skeletal myotubes: an activation defect caused by the hypokalemic periodic paralysis mutation R528H. J Neurosci 18:10320-10334
16. Niall JF, Pak Poy RK (1966) Studies in familial hypokalaemic periodic paralysis. Australas Ann Med 15:352-358
17. Nowycky MC, Fox AP, Tsien RW (1985) Long-opening mode of gating of neuronal calcium channels and its promotion by the dihydropyridine calcium agonist Bay K 8644. Proc Natl Acad Sci USA 82:2178-2182
18. Pietrobon D, Hess P (1990) Novel mechanism of voltage-dependent gating in L-type calcium channels. Nature 346:651-655
19. Ruff RL, Gordon AM (1986) Disorders of muscle. The periodic paralyses. In: Andreoli TE, Hoffman JF, Fanestil DD, Schultz SG (eds) Physiology of membrane disorders, 2nd edn. Plenum, New York, NY, pp 825-839
20. Shy GM, Wanko T, Rowley PT, Engel AG (1961) Studies in familial periodic paralysis. Exp Neurol 3:53-121
21. Stevens CF (1978) Interactions between intrinsic membrane protein and electric field. An approach to studying nerve excitability. Biophys J 22:295-306
22. Sun L, Fan JS, Clark JW, Palade PT (2000) A model of the L-type Ca2+ channel in rat ventricular myocytes: ion selectivity and inactivation mechanisms. J Physiol 529:139-158