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34249864675
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Frey EK, Kraut H, Werle E: Kallikrein (Padutin). Ferdinand Enke Verlag, Stuttgart, Germany (1950). •• This monograph was translated from German into English in 1977. The book provides a comprehensive review of the foundation of the kallikrein-kinin system.
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Frey EK, Kraut H, Werle E: Kallikrein (Padutin). Ferdinand Enke Verlag, Stuttgart, Germany (1950). •• This monograph was translated from German into English in 1977. The book provides a comprehensive review of the foundation of the kallikrein-kinin system.
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2
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34249898245
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Frey EK, Kraut H, Werle E, Vogel R, Zickgraf-Rüdel G, Trautschold I: Das Kallikrein-kinin-system und Seine Inhibitoren. Ferdinand Enke Verlag, Stuttgart, Germany (1968). • Soon after the discovery of tissue kallikrein a series of manuscripts were published in Biochemie Zeitschrift on the presence of kallikrein inhibitors in the circulation and organ tissues. This monograph collates this early research, from which inspiration has been drawn for the characterization of kallikrein inhibitors.
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Frey EK, Kraut H, Werle E, Vogel R, Zickgraf-Rüdel G, Trautschold I: Das Kallikrein-kinin-system und Seine Inhibitoren. Ferdinand Enke Verlag, Stuttgart, Germany (1968). • Soon after the discovery of tissue kallikrein a series of manuscripts were published in Biochemie Zeitschrift on the presence of kallikrein inhibitors in the circulation and organ tissues. This monograph collates this early research, from which inspiration has been drawn for the characterization of kallikrein inhibitors.
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3
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10444240277
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Inhibition of plasma kallikrein by C1-inhibitor: Role of endothelial cells and the amino-terminal domain of C1-inhibitor
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Ravindran S, Grys TE, Welch RA, Schapira M, Patston PA: Inhibition of plasma kallikrein by C1-inhibitor: Role of endothelial cells and the amino-terminal domain of C1-inhibitor. Thromb Haemost (2004) 92(6):1277-1283.
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Bhoola K, Ramsaroop R, Plendl J, Cassim B, Dlamini Z, Naicker S: Kallikrein and kinin receptor expression in inflammation and cancer. Biol Chem (2001) 382(1):77-89. • This is one of the first publications to report the upregulation of hK1 in cancer, and delineate the carcinogenesis role of kinin peptides. The finding of hK1 expression during the formation of new capillaries by cultured microvascular endothelial cells is described.
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Bhoola K, Ramsaroop R, Plendl J, Cassim B, Dlamini Z, Naicker S: Kallikrein and kinin receptor expression in inflammation and cancer. Biol Chem (2001) 382(1):77-89. • This is one of the first publications to report the upregulation of hK1 in cancer, and delineate the carcinogenesis role of kinin peptides. The finding of hK1 expression during the formation of new capillaries by cultured microvascular endothelial cells is described.
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5
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Bhoola KD, Figueroa CD, Worthy K: Bioregulation of kinins: Kallikreins, kininogens and kininases. Pharmacol Rev (1992) 44(1):1-80. •• A critical review of the literature on kinins published from the early 1900s to 1992.
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Bhoola KD, Figueroa CD, Worthy K: Bioregulation of kinins: Kallikreins, kininogens and kininases. Pharmacol Rev (1992) 44(1):1-80. •• A critical review of the literature on kinins published from the early 1900s to 1992.
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6
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78650583245
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Kallikrein-kinin cascade
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Laurent G, Shapiro SD Eds, Elsevier Ltd, Oxford, UK
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Bhoola KD, Fink E: Kallikrein-kinin cascade. In: Encyclopaedia of Respiratory Medicine. Laurent G, Shapiro SD (Eds), Elsevier Ltd, Oxford, UK (2006):483-493.
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Encyclopaedia of Respiratory Medicine
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Bhoola, K.D.1
Fink, E.2
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0022480680
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Chao J, Tillman DM, Wang MY, Margolius HS, Chao L: Identification of a new tissue-kallikrein-binding protein. Biochem J (1986) 239(2):325-331. •• A seminal article that reports the discovery of kallistatin. The biochemical properties of this serine protease inhibitor are described for the first time, which led to influential publications on the molecular mechanisms by which kallistatin interacts with hK1, resulting in the inhibition of hK1.
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Chao J, Tillman DM, Wang MY, Margolius HS, Chao L: Identification of a new tissue-kallikrein-binding protein. Biochem J (1986) 239(2):325-331. •• A seminal article that reports the discovery of kallistatin. The biochemical properties of this serine protease inhibitor are described for the first time, which led to influential publications on the molecular mechanisms by which kallistatin interacts with hK1, resulting in the inhibition of hK1.
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8
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Inhibition profiles of human tissue kallikreins by serine protease inhibitors
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Luo LY, Jiang W: Inhibition profiles of human tissue kallikreins by serine protease inhibitors. Biol Chem (2006) 387(6):813-816.
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Recombinant production, purification and biochemical characterization of domain 6 of LEKTI: A temporary Kazal-type-related serine proteinase inhibitor
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Kreutzmann P, Schulz A, Standker L, Forssmann WG, Magert HJ: Recombinant production, purification and biochemical characterization of domain 6 of LEKTI: A temporary Kazal-type-related serine proteinase inhibitor. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 803(1):75-81.
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28244435723
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Schechter NM, Choi EJ, Wang ZM, Hanakawa Y, Stanley JR, Kang Y, Clayman GL, Jayakumar A: Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI). Biol Chem (2005) 386(11):1173-1184. •• This research paper describes the expression of hK5 and hK7 in the skin, and their inhibition by LEKTI. Mutations of LEKTI are considered to be implicated in the inherited skin disorder, the Netherton syndrome, typified by severe skin scaling.
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Schechter NM, Choi EJ, Wang ZM, Hanakawa Y, Stanley JR, Kang Y, Clayman GL, Jayakumar A: Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI). Biol Chem (2005) 386(11):1173-1184. •• This research paper describes the expression of hK5 and hK7 in the skin, and their inhibition by LEKTI. Mutations of LEKTI are considered to be implicated in the inherited skin disorder, the Netherton syndrome, typified by severe skin scaling.
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33744951683
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Hekim C, Leinonen J, Narvanen A, Koistinen H, Zhu L, Koivunen E, Vaisanen V, Stenman UH: Novel peptide inhibitors of human kallikrein 2. J Biol Chem (2006) 281(18):12555-12560. •• This paper reports a novel concept that utilizes the enzymic activity of hK2 to deliver an anticancer drug.
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Hekim C, Leinonen J, Narvanen A, Koistinen H, Zhu L, Koivunen E, Vaisanen V, Stenman UH: Novel peptide inhibitors of human kallikrein 2. J Biol Chem (2006) 281(18):12555-12560. •• This paper reports a novel concept that utilizes the enzymic activity of hK2 to deliver an anticancer drug.
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9444268199
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Janssen S, Jakobsen CM, Rosen DM, Ricklis RM, Reineke U, Christensen SB, Lilja H, Denmeade SR: Screening a combinatorial peptide library to develop a human glandular kallikrein 2-activated prodrug as targeted therapy for prostate cancer. Mol Cancer Ther (2004) 3(11):1439-1450. •• This paper describes the use of a combinatorial tetrapeptide library as an investigative tool for the identification of new peptide inhibitors. Prostate cancer cells secrete hK2, which can uniquely act as a target for proteolytic activation of cytotoxic drugs. This novel concept, if developed clinically, could have a major impact on cancer therapy, in particular in the treatment of prostate cancer.
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Janssen S, Jakobsen CM, Rosen DM, Ricklis RM, Reineke U, Christensen SB, Lilja H, Denmeade SR: Screening a combinatorial peptide library to develop a human glandular kallikrein 2-activated prodrug as targeted therapy for prostate cancer. Mol Cancer Ther (2004) 3(11):1439-1450. •• This paper describes the use of a combinatorial tetrapeptide library as an investigative tool for the identification of new peptide inhibitors. Prostate cancer cells secrete hK2, which can uniquely act as a target for proteolytic activation of cytotoxic drugs. This novel concept, if developed clinically, could have a major impact on cancer therapy, in particular in the treatment of prostate cancer.
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Janssen S, Rosen DM, Ricklis RM, Dionne CA, Lilja H, Christensen SB, Isaacs JT, Denmeade SR: Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug. Prostate (2006) 66(4):358-368. •• A cutting edge study on the development of a drug delivery system based on the concept described in reference [35].
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Janssen S, Rosen DM, Ricklis RM, Dionne CA, Lilja H, Christensen SB, Isaacs JT, Denmeade SR: Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug. Prostate (2006) 66(4):358-368. •• A cutting edge study on the development of a drug delivery system based on the concept described in reference [35].
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