The alloantigenic sites of α3α4α5(IV) collagen: Pathogenic X-linked alport alloantibodies target two accessible conformational epitopes in the α5NC1 domain

Journal of Biological Chemistry

Volumn 282, Issue 14, 2007, Pages 10670-10677

  Jeong, Suk Kang ^a   Kashtan, Clifford E ^b   Turner, A Neil ^c   Heidet, Laurence ^d   Hudson, Billy G ^a   Borza, Dorin Bogdan ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIBODIES; ALLOANTIGENIC SITES; X-LINKED ALPORT SYNDROME (XLAS);

ANTIBODIES; BINDING SITES; CONFORMATIONS; PATHOGENS; PATIENT MONITORING; TRANSPLANTS;

COLLAGEN;

ALLOANTIBODY; ALLOANTIGEN; COLLAGEN TYPE 4; GLOMERULUS BASEMENT MEMBRANE ANTIBODY; EPITOPE;

ALPORT SYNDROME; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHIMERA; CONTROLLED STUDY; EMBRYO; EPITOPE MAPPING; GLOMERULONEPHRITIS; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; KIDNEY ALLOGRAFT; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TARGETING; ADULT; ALLOTRANSPLANTATION; GENETICS; HISTOCOMPATIBILITY; IMMUNOLOGY; KIDNEY TRANSPLANTATION; MALE; NEPHRITIS; PROTEIN TERTIARY STRUCTURE;

MAMMALIA;

ADULT; COLLAGEN TYPE IV; EPITOPE MAPPING; EPITOPES, B-LYMPHOCYTE; HUMANS; ISOANTIBODIES; ISOANTIGENS; KIDNEY TRANSPLANTATION; MALE; NEPHRITIS; NEPHRITIS, HEREDITARY; PROTEIN STRUCTURE, TERTIARY; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HOMOLOGOUS;

EID: 34249857120     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611892200     Document Type: Article

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