The heart-brain interaction during emotionally provoked myocardial ischemia: Implications of cortical hyperactivation in CAD and gender interactions

Cleveland Clinic Journal of Medicine

Volumn 74, Issue SUPPL.1, 2007, Pages 59-62

  Soufer, Robert ^a   Burg, Matthew M ^a,b  

^a YALE UNIVERSITY   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN CORTEX; HEART MUSCLE ISCHEMIA; HUMAN; MENTAL STRESS; PATHOPHYSIOLOGY; REVIEW; SEX DIFFERENCE;

CEREBRAL CORTEX; HUMANS; MYOCARDIAL ISCHEMIA; SEX FACTORS; STRESS, PSYCHOLOGICAL;

EID: 34249847331     PISSN: 08911150     EISSN: None     Source Type: Journal    
DOI: 10.3949/ccjm.74.Suppl_1.S59     Document Type: Article

References (24)

1. Chrousos GP. Stressors, stress, and neuroendocrine integration of the adaptive response. Ann NY Acad Sci 1998; 851:311-315.
2. Burg MM, Vashist A, Soufer R. Mental stress ischemia: present status and future goals. J Nucl Cardiol 2005; 12:523-529.
3. Burg MM, Jain D, Soufer R, et al. Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease. J Am Coll Cardiol 1993; 22:440-448.
4. Sheps DS, McMahon RP, Becker L, et al. Mental stress-induced ischemia and all-cause mortality in patients with coronary artery disease: results from the Psychophysiological Investigations of Myocardial Ischemia study. Circulation 2002; 105:1780-1784.
5. Wittstein IS, Thiemann DR, Lima JA. Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med 2005; 352:539-548.
6. Sasaki N, Kinugawa T, Yamawaki M, et al. Transient left ventricular apical ballooning in a patient with bicuspid aortic valve created a left ventricular thrombus leading to acute renal infarction. Circ J 2004; 68:1081-1083.
7. Mittleman MA, Maclure M, Sherwood JB, et al. Triggering of acute myocardial infarction onset by episodes of anger. Circulation 1995; 92:1720-1725.
8. Lampert R, Joska T, Burg MM, Batsford WP, McPherson CA, Jain D. Emotional and physical precipitants of ventricular arrhythmia. Circulation 2002; 106:1800-1805.
9. Burg MM, Lampert R, Joska T, Batsford W, Jain D. Psychological traits and emotion-triggering of ICD shock-terminated arrhythmias. Psychosom Med 2004; 66:898-902.
10. Schang SJ, Pepine CJ. Transient asymptomatic S-T segment depression during daily activity. Am J Cardiol 1977; 39:396-402.
11. Soufer R, Bremner JD, Arrighi JA. Cerebral cortical hyperactivation in response to mental stress in patients with coronary artery disease. Proc Natl Acad Sci USA 1998; 95:6454-6459.
12. Deanfield JE, Shea M, Kensett M, et al. Silent myocardial ischaemia due to mental stress. Lancet 1984; 2:1001-1005.
13. Yeung AC, Vekshtein VI, Krantz DS, et al. The effect of atherosclerosis on the vasomotor response of coronary arteries to mental stress. N Engl J Med 1991; 325:1551-1556.
14. Arrighi JA, Burg M, Cohen IS, et al. Myocardial blood-flow response during mental stress in patients with coronary artery disease. Lancet 2000; 356:310-311.
15. Jain D, Burg M, Soufer R, Zaret BL. Prognostic implications of mental stress-induced silent left ventricular dysfunction in patients with stable angina pectoris. Am J Cardiol 1995; 76:31-35.
16. Jiang W, Babyak M, Krantz DS, et al. Mental stress-induced myocardial ischemia and cardiac events. JAMA 1996; 275:1651-1656.
17. Krantz DS, Santiago HT, Kop WJ, Bairey Merz CN, Rozansk A, Gottdiener JS. Prognostic value of mental stress testing in coronary artery disease. Am J Cardiol 1999; 84:1292-1297.
18. Blumenthal JA, Babyak M, Wei J, et al. Usefulness of psychosocial treatment of mental stress-induced myocardial ischemia in man. Am J Cardiol 2002; 89:164-168.
19. Blumenthal JA, Jiang W, Babyak MA, et al. Stress management and exercise training in cardiac patients with myocardial ischemia. Effects on prognosis and evaluation of mechanisms. Arch Intern Med 1997; 157:2213-2223.
20. Shah R, Burg MM, Vashist A, et al. C-Reactive protein and vulnerability to mental stress-induced myocardial ischemia. Mol Med. In press.
21. Arrighi JA, Burg M, Cohen IS, Soufer R. Simultaneous assessment of myocardial perfusion and function during mental stress in patients with chronic coronary artery disease. J Nucl Cardiol 2003; 10:267-274.
22. Lincoln T. Brain, heart, and stress [comment]. Nature 1998; 393:523.
23. Soufer R, Bremner JD, Burg MM. Gender differences among normal and coronary disease subjects during mental stress: a positron emission tomography study. Presented at: American Psychosomatic Society 63rd Annual Meeting; March 2-5, 2005; Vancouver, BC, Canada.
24. Vashist A, Burg MM, Arrighi JA, et al. Central nervous system correlates of myocardial ischemia: neurocardiac distinctions between mental stress and dobutamine provocation. Presented at: American Psychosomatic Society 63rd Annual Meeting; March 2-5, 2005; Vancouver, BC, Canada.