Editorial: Aryl hydrocarbon receptor interacting protein and pituitary tumorigenesis: Another interesting protein

Journal of Clinical Endocrinology and Metabolism

Volumn 92, Issue 5, 2007, Pages 1617-1619

  Melmed, Shlomo ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CORTICOTROPIN; FOLLITROPIN; GROWTH HORMONE; LUTEINIZING HORMONE; PROLACTIN; THYROTROPIN; ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN; ARYL HYDROCARBON RECEPTOR-INTERACTING PROTEIN; CYCLIC AMP; PROTEIN; UNCLASSIFIED DRUG;

ACROMEGALY; ADENOHYPOPHYSIS; ALBRIGHT SYNDROME; CARCINOGENESIS; CARCINOID; CARNEY COMPLEX; CELL DIVISION; EDITORIAL; FAMILIAL DISEASE; GENE MUTATION; GONADOTROPIN SECRETING CELL; GROWTH HORMONE SECRETING ADENOMA; HORMONE RELEASE; HORMONE SYNTHESIS; HUMAN; HYPERPLASIA; HYPOPHYSIS ADENOMA; HYPOPHYSIS HYPERPLASIA; HYPOPHYSIS TUMOR; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; GENETICS; METABOLISM; MUTATION; NOTE; PATHOLOGY; STOP CODON;

ACROMEGALY; CELL DIVISION; CODON, NONSENSE; CYCLIC AMP; GERM-LINE MUTATION; HUMANS; MUTATION; PITUITARY NEOPLASMS; PROTEINS;

EID: 34249846437     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-0595     Document Type: Editorial

References (36)

1. Olson LE, Rosenfeld MG 2002 Perspective: genetic and genomic approaches in elucidating mechanisms of pituitary development. Endocrinology 143:2007-2011
2. Melmed S 2003 Mechanisms for pituitary tumorigenesis: the plastic pituitary. J Clin Invest 112:1603-1618
3. Asa SL, Ezzat S 2005 Genetics and proteomics of pituitary tumors. Endocrine 28:43-47
4. Levy A, Lightman S 2003 Molecular defects in the pathogenesis of pituitary tumours. Front Neuroendocrinol 24:94-127
5. Thorner MO, Perryman RL, Cronin MJ, Rogol AD, Draznin M, Johanson A, Vale W, Horvath E, Kovacs K 1982 Somatotroph hyperplasia. Successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor. J Clin Invest 70:965-977
6. Pei L, Melmed S 1997 Isolation and characterization of a pituitary tumor-transforming gene (PTTG). Mol Endocrinol 11:433-441
7. Ezzat S, Zheng L, Zhu XF, Wu GE, Asa SL 2002 Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis. J Clin Invest 109:69-78
8. Fedele M, Pierantoni GM, Visone R, Fusco A 2006 Critical role of the HMGA2 gene in pituitary adenomas. Cell Cycle 5:2045-2048
9. Bilodeau S, Vallette-Kasic S, Gauthier Y, Figarella-Branger D, Brue T, Berthelet F, Lacroix A, Batista D, Stratakis C, Hanson J, Meij B, Drouin J 2006 Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease. Genes Dev 20:2871-2886
10. Riss D, Jin L, Qian X, Bayliss J, Scheithauer BW, Young Jr WF, Vidal S, Kovacs K, Raz A, Lloyd RV 2003 Differential expression of galectin-3 in pituitary tumors. Cancer Res 63:2251-2255
11. Shimon I, Huttner A, Said J, Spirina OM, Melmed S 1996 Heparin-binding secretory transforming gene (hst) facilitates rat lactotrope cell tumorigenesis and induces prolactin gene transcription. J Clin Invest 97:187-195
12. Simpson DJ, Bicknell EJ, Buch HN, Cutty SJ, Clayton RN, Farrell WE 2003 Genome-wide amplification and allelotyping of sporadic pituitary adenomas identify novel regions of genetic loss. Genes Chromosomes Cancer 37:225-236
13. Thakker RV, Pook MA, Wooding C, Boscaro M, Scanarini M, Clayton RN 1993 Association of somatotrophinomas with loss of alleles on chromosome 11 and with gsp mutations. J Clin Invest 91:2815-2821
14. Zhang X, Sun H, Danila DC, Johnson SR, Zhou Y, Swearingen B, Klibanski A 2002 Loss of expression of GADD45 γ, a growth inhibitory gene, in human pituitary adenomas: implications for tumorigenesis. J Clin Endocrinol Metab 87:1262-1267
15. Bates AS, Farrell WE, Bicknell EJ, McNicol AM, Talbot AJ, Broome JC, Perrett CW, Thakker RV, Clayton RN 1997 Allelic deletion in pituitary adenomas reflects aggressive biological activity and has potential value as a prognostic marker. J Clin Endocrinol Metab 82:818-824
16. Vallar L, Spada A, Giannattasio G 1987 Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomas. Nature 330:566-568
17. Crabtree JS, Scacheri PC, Ward JM, Garrett-Beal L, Emmert-Buck MR, Edgemon KA, Lorang D, Libutti SK, Chandrasekharappa SC, Marx SJ, Spiegel AM, Collins FS 2001 A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors. Proc Natl Acad Sci USA 98:1118-1123
18. Weinstein LS, Shenker A, Gejman PV, Merino MJ, Friedman E, Spiegel AM 1991 Activating mutations of the stimulatory G protein in the McCune-Albright syndrome. N Engl J Med 325:1688-1695
19. Kirschner LS, Sandrini F, Monbo J, Lin JP, Carney JA, Stratakis CA 2000 Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the Carney complex. Hum Mol Genet 9:3037-3046
20. Boikos SA, Stratakis CA 2007 Carney complex: the first 20 years. Curr Opin Oncol 19:24-29
21. Frohman LA, Eguchi K 2004 Familial acromegaly. Growth Horm IGF Res 14(Suppl A):S90-S96
22. Gadelha MR, Une KN, Rohde K, Vaisman M, Kineman RD, Frohman LA 2000 Isolated familial somatotropinomas: establishment of linkage to chromosome 11q13.1-11q13.3 and evidence for a potential second locus at chromosome 2p16-12. J Clin Endocrinol Metab 85:707-714
23. Melmed S 2006 Medical progress: acromegaly. N Engl J Med 355:2558-2573
24. Barlier A, Vanbellinghen JF, Daly AF, Silvy M, Jaffrain-Rea ML, Trouillas J, Tamagno G, Cazabat L, Bours V, Brue T, Enjalbert A, Beckers A 2007 Mutations in the aryl hydrocarbon receptor interacting protein gene are not highly prevalent among subjects with sporadic pituitary adenomas. J Clin Endocrinol Metab 92:1952-1955
25. Daly AF, Vanbellinghen JF, Khoo SK, Jaffrain-Rea ML, Naves LA, Guitelman MA, Murat A, Emy P, Gimenez-Roqueplo AP, Tamburrano G, Raverot G, Barlier A, De Herder W, Penfornis A, Ciccarelli E, Estour B, Lecomte P, Gatta B, Chabre O, Sabate MI, Bertagna X, Garcia Basavilbaso N, Stalldecker G, Colao A, Ferolla P, Wemeau JL, Caron P, Sadoul JL, Oneto A, Archambeaud F, Calender A, Sinilnikova O, Montanana CF, Cavagnini F, Hana V, Solano A, Delettieres D, Luccio-Camelo DC, Basso A, Rohmer V, Brue T, Bours V, Teh BT, Beckers A 2007 Aryl hydrocarbon receptor interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families. J Clin Endocrinol Metab 92:1891-1896
26. Toledo RA, Lourenco Jr DM, Liberman B, Cunha-Neto MB, Cavalcanti MG, Moyses CB, Toledo SP, Dahia PL 2007 Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma. J Clin Endocrinol Metab 92:1934-1937
27. Vierimaa O, Georgitsi M, Lehtonen R, Vahteristo P, Kokko A, Raitila A, Tuppurainen K, Ebeling TM, Salmela PI, Paschke R, Gundogdu S, De Menis E, Makinen MJ, Launonen V, Karhu A, Aaltonen LA 2006 Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science 312:1228-1230
28. Yu R, Bonert V, Saporta I, Raffel LJ, Melmed S 2006 Aryl hydrocarbon receptor interacting protein variants in sporadic pituitary adenomas. J Clin Endocrinol Metab 91:5126-5129
29. Iwata T, Yamada S, Mizusawa N, Golam H, Sano T, Yoshimoto K 2007 The aryl hydrocarbon receptor-interacting protein gene is rarely mutated in sporadic GH-secreting adenomas. Clin Endocrinol (Oxf) 66:499-502
30. Georgitsi M, Raitila A, Karhu A, Tuppurainen K, Makinen M, Vierimaa O, Paschke R, Saeger W, van der Luijt RB, Sane T, Robledo M, De Menis E, Weil RJ, Wasik A, Zielinski G, Lucewicz O, Lubinski L, Launonen V, Vahteristo P, Aaltonen LA 2007 Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations. Proc Natl Acad Sci USA 104:4101-4105
31. Ema M, Ohe N, Suzuki M, Mimura J, Sogawa K, Ikawa S, Fujii-Kuriyama Y 1994 Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors. J Biol Chem 269:27337-27343
32. Carver LA, Bradfield CA 1997 Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. J Biol Chem 272:11452-11456
33. Bell DR, Poland A 2000 Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein. The role of hsp90. J Biol Chem 275:36407-36414
34. McPhee I, Pooley L, Lobban M, Bolger G, Houslay MD 1995 Identification, characterization and regional distribution in brain of RPDE-6 (RNPDE4A5), a novel splice variant of the PDE4A cyclic AMP phosphodiesterase family. Biochem J 310(Pt 3):965-974
35. Landis CA, Masters SB, Spada A, Pace AM, Bourne HR, Vallar L 1989 GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 340:692-696
36. Daly AF, Jaffrain-Rea ML, Ciccarelli A, Valdes-Socin H, Rohmer V, Tamburrano G, Borson-Chazot C, Estour B, Ciccarelli E, Brue T, Ferolla P, Emy P, Colao A, De Menis E, Lecomte P, Penfornis F, Delemer B, Bertherat J, Wemeau JL, De Herder W, Archambeaud F, Stevenaert A, Calender A, Murat A, Cavagnini F, Beckers A 2006 Clinical characterization of familial isolated pituitary adenomas. J Clin Endocrinol Metab 91:3316-3323