Computer simulation to study inflammatory response

Simulation and Gaming

Volumn 32, Issue 3, 2001, Pages 344-361

  An, Gary ^a   Lee, Irene Anne ^b  

^a Jr Hospital of Cook County   (United States)

^b NONE   (United States)

Author keywords

Agent based modeling; Complex systems; Computer simulation; Critical care medicine; Inflammation; Medical simulation; Nonlinear; Pharmacology; Sepsis; Shock; Trauma

Indexed keywords

EID: 34249821289     PISSN: 10468781     EISSN: 1552826X     Source Type: Journal    
DOI: 10.1177/104687810103200305     Document Type: Article

References (29)

1. Auyang, S. Y. (1998). Foundations of complex-system theories in economics, evolutionary biology and statistical physics. Cambridge, UK: Cambridge University Press.
2. Barbeau, L.J.A., & Dececchi, T. (1997). A framework for the object-oriented design and simulation of information system dynamics. Simulation & Gaming: An Interdisciplinary Journal, 28(1), 44-64.
3. Baue, A. E. (1992). The horror autotoxicus and multiple-organ failure. Archives of Surgery, 127(12), 1451-1462.
4. Bone, R. C. (1996). Sir Isaac Newton, sepsis, SIRS, and CARS. Critical Care Medicine, 24(7), 1125-1128.
5. Buchman, T. G. (1996). Physiologic stability and physiologic state. Journal of Trauma, 41(4), 599-605.
6. Butler, R. J., Markulis, P. M., & Strang, D. R. (1988). Where are we? An analysis of the methods and focus of the research on simulation gaming. Simulation & Games, 19(1), 3-26.
7. Casti, J. L. (1994). Complexification: Explaining a paradoxical world through the science of surprise. New York: Harper Collins.
8. Chernow, B. (1996). Back to the drawing board. Critical Care Medicine, 24(7), 1097-1098.
9. Cilliers, P. (1998). Complexity and postmode rnism: Understanding complex systems. New York: Routledge.
10. Estes, C. R. (1994). The real-world connection. Simulation & Gaming, 25(4), 456-463.
11. Fisher, C. J., Agosti, J. M., Opal, S. M., Lowry, S. F., Balk, R. A., Sadoff, J. C., Abraham, E., Schein, R. M. H., & Benjamin, E. (1996). Treatment of septic shock with tumor necrosis factor receptor: Fc fusion protein. New England Journal of Medicine, 334(26), 1697-1702.
12. Gaviria, J. M., Dale, D. C., & Root, R. K. (1998). Neutrophils: Function and role in sepsis syndrome. Sepsis, 2, 107-117.
13. Godin, P. J., & Buchman, T. G. (1996). Uncoupling of biologic oscillators: A complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome. Critical Care Medicine, 24(7), 1107-1116.
14. Hauser, C. J. (1996). Regional macrophage activation after injury and the compartmentalization of inflammation in trauma. New Horizons, 4(2), 235-251.
15. Hirshberg, A., Sheffer, N., & Barnea, O. (1999). Computer simulation of hypothermia during "damage control" laparotomy. World Journal of Surgery, 23(9), 960-965.
16. Holland, J. H. (1995). Hidden order: How adaptation builds complexity. Reading, MA: Perseus Books.
17. Maier, R. V., & Bulger, E. M. (1996). Endothelial Changes after Shock and Injury. New Horizons, 4(2), 211-223.
18. McCloskey, R. V., Straube, R. C., Sanders, C., Smith, S. M., & Smith, C. R. (1994). Treatment of septic shock with human monoclonal antibody HA-1A. Annals of Internal Medicine, 121(1), 1-5.
19. Millians, D. (1999). Thirty years and more of simulations and games. Simulation & Gaming, 30(3), 352-355.
20. Nasraway, S. A., Jr. (1999). Sepsis research: We must change course. Critical Care Medicine, 27(2), 427-430.
21. Natanson, C., Esposito, C. J., & Banks, S. M. (1998). The sirens' song of confirmatory sepsis trials: Selection bias and sampling error. Critical Care Medicine, 26(12), 1927-1930.
22. Oreskes, N., Shrader-Frechette, K., & Belitz, K. (1994). Verification, validation and confirmation of numerical models in the earth sciences. Science, 263, 641-646.
23. Partrick, D. A., Moore, F. A., Moore, E. E., Barnett, C. C., Jr., & Silliman, C. C. (1996). Neutrophil priming and activation in the pathogenesis of postinjury multiple organ failure. New Horizons, 4(2), 194-210.
24. Peters, V., Vissers, G., & Heijne, G. (1998). The validity of games. Simulation & Gaming, 29(1), 20-30.
25. Resnick, M. (1994). Turtles, termites, and traffic jams: Explorations in massively parallel microworlds. Cambridge, UK: Bradford.
26. Sheffer, N., Hirshberg, A., & Barnea, O. (1997). Myocardial 02 balance during fluid resuscitation in uncontrolled hemorrhage: Computer model. Journal of Trauma, 42(4), 647-651.
27. Tracey, K. J., & Abraham, E. (1999). From mouse to man: or What have we learned about cytokine-based anti-inflammatory therapies? Shock, 11(3), 224-225.
28. Wolfe, J., & Crookall, D. (1998). Developing a scientific knowledge of simulation/gaming. Simulation & Gaming, 29(1), 7-19.
29. Zimmerman, J. J. (1999). A question of balance. Critical Care Medicine, 27(1), 7-8.