Synthesis, physical properties, antimicrobial potentials of some antibiotics complexed with transition metals and their effects on alkaline phosphatase activities of selected rat tissues

African Journal of Biotechnology

Volumn 6, Issue 10, 2007, Pages 1202-1208

  Ogunniran, K O ^a   Tella, A C ^b   Alensela, M ^c   Yakubu, M T ^b  

^a Centre for Economic Policy and Development Research   (Nigeria)

^b UNIVERSITY OF ILORIN   (Nigeria)

^c IGBINEDION UNIVERSITY   (Nigeria)

Author keywords

Alkaline phosphatase; Antibiotics; Antimicrobial properties; Complexation; Metal complexes

Indexed keywords

ALKALINE PHOSPHATASE; AMPICILLIN; CHLORAMPHENICOL; COBALT PLUS AMPICILLIN; COBALT PLUS CHLORAMPHENICOL; IRON PLUS AMPICILLIN; IRON PLUS CHLORAMPHENICOL; IRON PLUS OXYTETRACYCLINE; METAL COMPLEX; NICKEL PLUS AMPICILLIN; NICKEL PLUS CHLORAMPHENICOL; NICKEL PLUS OXYTETRACYCLINE; OXYTETRACYCLINE; TRANSITION ELEMENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG INHIBITION; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ESCHERICHIA COLI; KIDNEY; KLEBSIELLA PNEUMONIAE; LIVER; NONHUMAN; RAT; STAPHYLOCOCCUS AUREUS;

ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; RATTUS; STAPHYLOCOCCUS AUREUS;

EID: 34249813420     PISSN: None     EISSN: 16845315     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. nd edition. Sharson Jersey, pp. 28-446.
2. Akanji MA, Olagoke OA, Oloyede OB (1993). Effect of chronic consumption of metabisulphite on the integrity of the kidney cellular system. Toxicol. 81: 173-179.
3. Albert FC, Geoffery W (1987). Advanced Inorganic Chemistry. 6th edition. John Wiley and Sons, NY. pp. 85.
4. Butterworth PJ, Moss DW (1966): The effect of urea on human kidney alkaline phosphatase. Biochem. J. 99: 9-10.
5. Chamber C, Holiday AF (1983). Modern Inorganic Chemistry. 2nd edition. Butterworths and Co. Ltd., pp. 401-407.
6. rd edition. Butterworths and Co. Ltd., pp. 414-427.
7. th edition. Little Brown and Co., Boston. pp. 653-655.
8. th edition. Prentice-Hall Inc., New Jersey. Pp. 225.
9. th edition. ELBS, Longman. pp. 881-882.
10. Gornall AC, Bardawill CJ, David MM (1949). Determination of serum protein by means of biuret reaction. J. Biol. Chem., 177: 751-756.
11. Kemp W (1979). Organic spectroscopy. ELBS. Oxford University Press, England. pp. 35-64.
12. Nadira W, Singh HB (1987). Synthesis of metal complexes of antimalarial drugs and their activity. Inorg. Chim. Acta, 135: 134-137.
13. Obaleye JA, Fawurewa O (1989). Inhibitory effect of some inorganic Borontrifluoride complexes on some microorganisms. Biosci. Res. Comm. 1: 87-93.
14. Obaleye JA, Nde-aga JB, Balogun EA (1997). Some antimalaria drug metal complexes, synthesis, characterization and their in vivo evaluation against malaria parasite. Afr. J. Sci. 1: 10-12.
15. Shahjahan M, Sabitha KE, Mallika J, Shyamala-Devi CS (2004). Effect of Solanum trilobatum against carbon tetrachloride induced hepatic damage in albino rats. Indian J. Med. Res. 120: 194-198.
16. Umezawa H, Hooper IR (1982). Amino-glycoside antibiotic. Springer-Verlag Berlin, Hadelberg, New York.
17. th edition. John Wiley Inc., England. pp. 133-315.
18. Wright PJ, Leathwood PD, Plummer DT (1972a). Enzymes in rat urine. Alkaline phosphatase. Enzymologia, 42: 317-327.
19. Wright PJ, Plummer DT (1974). The use of urinary enzyme measurement to detect renal damages caused by nephrotoxic compounds. Biochem. Pharmacol., 12: 65.
20. Yakubu MT (2006). Aphrodisiac potentials and toxicological evaluation of aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male rats. Ph. D. Thesis, University of Ilorin, Ilorin, Nigeria.
21. Yakubu MT, Akanji MA, Oladiji AT (2005). Aphrodisiac potentials of aqueous extract of Fadogia agrestis (Schweinf. Ex Heirn) stem in male albino rats. Asian J. Androl. 7(4): 399-404.